protein

RIBOSOMAL PROTEIN S6

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RIBOSOMAL PROTEIN S6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

110Connections

0Hypotheses

0Analyses

48Outgoing

50Incoming

0Experiments

0Debates

Summary

Page for Ribosomal Protein S6

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🔬 Protein Info

Gene Symbol	RIBOSOMAL PROTEIN S6
Molecular Weight	28.7 kDa
Pathways	mTOR, mtor, mTOR signaling, mTOR pathway
Interactions	ACTB, ALZHEIMER, APOE, ATG12, ATG7, CATHEPSIN B
KG Connections	110 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Pathway Diagram

graph TD
    RIBOSOMAL_PROTEIN_S6["RIBOSOMAL PROTEIN S6"]
    RUBICON["RUBICON"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| RUBICON
    LAMP1["LAMP1"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| LAMP1
    RAB7A["RAB7A"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| RAB7A
    ISCHEMIA["ISCHEMIA"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| ISCHEMIA
    MTORC1["MTORC1"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| MTORC1
    Epithelial_Cell["Epithelial Cell"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| Epithelial_Cell
    NADH["NADH"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| NADH
    INSULIN["INSULIN"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| INSULIN
    RAPAMYCIN["RAPAMYCIN"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| RAPAMYCIN
    PEROXISOME["PEROXISOME"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| PEROXISOME
    OPTINEURIN["OPTINEURIN"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| OPTINEURIN
    HSP70["HSP70"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| HSP70
    ENDOPHILIN["ENDOPHILIN"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| ENDOPHILIN
    P38_Mapk["P38 Mapk"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| P38_Mapk
    GABARAP["GABARAP"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| GABARAP
    GRP78["GRP78"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| GRP78
    VPS34["VPS34"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| VPS34
    IFNG["IFNG"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| IFNG
    cancer["cancer"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| cancer
    MAPK["MAPK"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| MAPK
    OXIDATIVE_PHOSPHORYLATION["OXIDATIVE PHOSPHORYLATION"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| OXIDATIVE_PHOSPHORYLATION
    Stem_Cell["Stem Cell"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| Stem_Cell
    disease["disease"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| disease
    Dendritic_Cell["Dendritic Cell"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| Dendritic_Cell
    CYP1A1["CYP1A1"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| CYP1A1
    DNA_DAMAGE["DNA DAMAGE"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| DNA_DAMAGE
    COLORECTAL_CANCER["COLORECTAL CANCER"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| COLORECTAL_CANCER
    Microrna["Microrna"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| Microrna
    Inflammatory_Bowel_Disease["Inflammatory Bowel Disease"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| Inflammatory_Bowel_Disease
    Reactive_Oxygen_Species["Reactive Oxygen Species"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| Reactive_Oxygen_Species

Outgoing (48)

Target	Relation	Type	Str
OXIDATIVE PHOSPHORYLATION	activates	pathway	0.50
Stem Cell	activates	cell_type	0.50
ENDOPHILIN	activates	protein	0.50
P38 Mapk	activates	pathway	0.50
GABARAP	activates	protein	0.50
GRP78	activates	protein	0.50
COLORECTAL CANCER	activates	disease	0.50
Microrna	activates	pathway	0.50
Inflammatory Bowel Disease	activates	disease	0.50
Reactive Oxygen Species	activates	process	0.50
RUBICON	activates	protein	0.50
LAMP1	activates	protein	0.50
RAB7A	activates	protein	0.50
ISCHEMIA	activates	disease	0.50
MTORC1	activates	concept	0.50
Epithelial Cell	activates	cell_type	0.50
NADH	activates	concept	0.50
INSULIN	activates	concept	0.50
RAPAMYCIN	activates	concept	0.50
PEROXISOME	activates	concept	0.50
EIF4E	interacts_with	protein	0.50
MTOR SIGNALING	interacts_with	concept	0.50
OPTINEURIN	activates	protein	0.50
HSP70	activates	protein	0.50
NUCLEUS	activates	concept	0.50
disease	activates	disease	0.50
Dendritic Cell	activates	cell_type	0.50
CYP1A1	activates	concept	0.50
DNA DAMAGE	activates	concept	0.50
MAP1LC3	activates	gene	0.50
CATHEPSIN B	activates	protein	0.50
ATG7	activates	protein	0.50
TUBULIN	activates	protein	0.50
SYNAPSIN I	activates	protein	0.50
ALZHEIMER	activates	gene	0.50
LYSOSOME	activates	gene	0.50
Alzheimer Disease	activates	disease	0.50
DMSO	activates	concept	0.50
PRKAA	activates	concept	0.50
Infection	activates	disease	0.50
Proteins	activates	protein	0.50
AUTOPHAGOSOME	activates	concept	0.50
MACROPHAGES	inhibits	concept	0.50
VPS34	activates	protein	0.50
IFNG	activates	gene	0.50
cancer	activates	disease	0.50
MAPK	activates	gene	0.50
ENDOPLASMIC RETICULUM	activates	concept	0.50

Incoming (62)

Source	Relation	Type	Str
LRRK2	activates	gene	0.50
Pi3K	activates	pathway	0.50
TFEB	activates	protein	0.50
EIF2A	activates	protein	0.50
STING1	activates	protein	0.50
RICTOR	activates	gene	0.50
EIF2AK3	activates	gene	0.50
DDIT3	activates	gene	0.50
OPTN	activates	gene	0.50
STAT3	activates	gene	0.50
DEPTOR	activates	gene	0.50
RIPK1	activates	gene	0.50
GABA	activates	gene	0.50
RHEB	activates	gene	0.50
MAVS	activates	gene	0.50
ULK1	activates	gene	0.50
APOE	inhibits	gene	0.50
mTOR	inhibits	entity	0.50
S6K1	inhibits	protein	0.50
GRB2	activates	gene	0.50
TFE3	activates	gene	0.50
GAPDH	activates	gene	0.50
EGFR	activates	gene	0.50
ACTB	activates	gene	0.50
Autophagy	activates	process	0.50
PPARGC1A	activates	gene	0.50
RPS6	activates	gene	0.50
CTSD	activates	gene	0.50
SQSTM1	activates	gene	0.50
mTOR	activates	entity	0.50
PPARG	activates	gene	0.50
MAP1LC3B	activates	gene	0.50
RPS6KB1	activates	gene	0.50
PPARA	activates	gene	0.50
PIK3C3	activates	gene	0.50
RUBCN	activates	gene	0.50
LRP2	activates	gene	0.50
SREBF1	activates	gene	0.50
EIF4EBP1	activates	gene	0.50
MLKL	activates	gene	0.50
FIP200	activates	gene	0.50
HSPA5	activates	gene	0.50
MAP1LC3A	activates	gene	0.50
MAPK14	activates	gene	0.50
HMGB1	activates	gene	0.50
ATG12	activates	gene	0.50
MCOLN1	activates	gene	0.50
mTOR	interacts_with	entity	0.50
ERN1	activates	gene	0.50
RB1CC1	activates	gene	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning RIBOSOMAL PROTEIN S6 in their description or question text

No additional research found