protein

SYNAPSIN I

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SYNAPSIN I: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

35Connections

0Hypotheses

0Analyses

13Outgoing

22Incoming

0Experiments

0Debates

Summary

Page for Synapsin I Protein

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🔬 Protein Info

Gene Symbol	SYNAPSIN I
Molecular Weight	80 kDa
Pathways	Synaptic Transmission
Interactions	ACTB, ALZHEIMER, AMPK, ATG7, CATHEPSIN B, CTSB
KG Connections	35 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Pathway Diagram

graph TD
    SYNAPSIN_I["SYNAPSIN I"]
    ALZHEIMER["ALZHEIMER"]
    SYNAPSIN_I -->|"activates"| ALZHEIMER
    Genes["Genes"]
    SYNAPSIN_I -->|"activates"| Genes
    LYSOSOME["LYSOSOME"]
    SYNAPSIN_I -->|"activates"| LYSOSOME
    Alzheimer_Disease["Alzheimer Disease"]
    SYNAPSIN_I -->|"activates"| Alzheimer_Disease
    disease["disease"]
    SYNAPSIN_I -->|"activates"| disease
    DMSO["DMSO"]
    SYNAPSIN_I -->|"activates"| DMSO
    PRKAA["PRKAA"]
    SYNAPSIN_I -->|"activates"| PRKAA
    Infection["Infection"]
    SYNAPSIN_I -->|"activates"| Infection
    Proteins["Proteins"]
    SYNAPSIN_I -->|"activates"| Proteins
    RAPAMYCIN["RAPAMYCIN"]
    SYNAPSIN_I -->|"activates"| RAPAMYCIN
    AUTOPHAGOSOME["AUTOPHAGOSOME"]
    SYNAPSIN_I -->|"activates"| AUTOPHAGOSOME
    AMPK["AMPK"]
    SYNAPSIN_I -->|"inhibits"| AMPK
    Differentiation["Differentiation"]
    SYNAPSIN_I -->|"inhibits"| Differentiation
    AMPK["AMPK"]
    SYNAPSIN_I -->|"activates"| AMPK
    Differentiation["Differentiation"]
    SYNAPSIN_I -->|"activates"| Differentiation
    Synaptic_Transmission["Synaptic Transmission"]
    SYNAPSIN_I -->|"inhibits"| Synaptic_Transmission
    TFEB["TFEB"]
    TFEB -->|"activates"| SYNAPSIN_I
    ACTB["ACTB"]
    ACTB -->|"activates"| SYNAPSIN_I
    Autophagy["Autophagy"]
    Autophagy -->|"activates"| SYNAPSIN_I
    CTSD["CTSD"]
    CTSD -->|"activates"| SYNAPSIN_I
    SQSTM1["SQSTM1"]
    SQSTM1 -->|"activates"| SYNAPSIN_I
    mTOR["mTOR"]
    mTOR -->|"activates"| SYNAPSIN_I
    MAP1LC3B["MAP1LC3B"]
    MAP1LC3B -->|"activates"| SYNAPSIN_I
    SYT1["SYT1"]
    SYT1 -->|"activates"| SYNAPSIN_I
    MAP2["MAP2"]
    MAP2 -->|"activates"| SYNAPSIN_I
    SNAP25["SNAP25"]
    SNAP25 -->|"activates"| SYNAPSIN_I
    TUBB3["TUBB3"]
    TUBB3 -->|"activates"| SYNAPSIN_I
    CTSB["CTSB"]
    CTSB -->|"activates"| SYNAPSIN_I
    SYN1["SYN1"]
    SYN1 -->|"activates"| SYNAPSIN_I
    RIBOSOMAL_PROTEIN_S6["RIBOSOMAL PROTEIN S6"]
    RIBOSOMAL_PROTEIN_S6 -->|"activates"| SYNAPSIN_I

Outgoing (13)

Target	Relation	Type	Str
AMPK	inhibits	protein	0.50
AMPK	activates	protein	0.50
Synaptic Transmission	inhibits	pathway	0.50
ALZHEIMER	activates	gene	0.50
LYSOSOME	activates	gene	0.50
Alzheimer Disease	activates	disease	0.50
disease	activates	disease	0.50
DMSO	activates	concept	0.50
PRKAA	activates	concept	0.50
Infection	activates	disease	0.50
Proteins	activates	protein	0.50
RAPAMYCIN	activates	concept	0.50
AUTOPHAGOSOME	activates	concept	0.50

Incoming (22)

Source	Relation	Type	Str
EPILEPSY	associated_with	gene	0.50
SYN2	associated_with	gene	0.50
SYN1	associated_with	gene	0.50
TFEB	activates	protein	0.50
ACTB	activates	gene	0.50
Autophagy	activates	process	0.50
CTSD	activates	gene	0.50
SQSTM1	activates	gene	0.50
mTOR	activates	entity	0.50
MAP1LC3B	activates	gene	0.50
SYT1	activates	gene	0.50
MAP2	activates	gene	0.50
SNAP25	activates	gene	0.50
TUBB3	activates	gene	0.50
CTSB	activates	gene	0.50
SYN1	activates	gene	0.50
RIBOSOMAL PROTEIN S6	activates	protein	0.50
LAMP1	activates	protein	0.50
CATHEPSIN B	activates	protein	0.50
ATG7	activates	protein	0.50
TUBULIN	activates	protein	0.50
TUBULIN	inhibits	protein	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SYNAPSIN I in their description or question text

No additional research found