concept

PEROXISOME

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PEROXISOME: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

142Connections

0Hypotheses

0Analyses

0Outgoing

50Incoming

0Experiments

0Debates

No summary available yet.

View on Wiki →

No AI portrait yet

💡 Concept Info

Name	PEROXISOME
Key Genes/Proteins	ACTB, amyotrophic lateral sclerosis, BAG3, CTSB, DDIT3, DEPTOR
Related Diseases	aging, cancer, CARCINOMA, disease
Related Pathways	Chaperone

Pathway Diagram

graph TD
    PEROXISOME["PEROXISOME"]
    PEROXISOME -->|"activates"| RAPAMYCIN["RAPAMYCIN"]
    PEROXISOME -->|"activates"| PGC_1ALPHA["PGC-1ALPHA"]
    PEROXISOME -->|"activates"| SQSTM1["SQSTM1"]
    PEROXISOME -->|"activates"| RAS["RAS"]
    PEROXISOME -->|"activates"| TFEB["TFEB"]
    PEROXISOME -->|"activates"| STEM_CELLS["STEM CELLS"]
    PEROXISOME -->|"activates"| PI3K["PI3K"]
    PEROXISOME -->|"activates"| ULK1["ULK1"]
    AUTOPHAGY["AUTOPHAGY"] -->|"activates"| PEROXISOME
    MTOR["MTOR"] -->|"activates"| PEROXISOME
    AMPK["AMPK"] -->|"activates"| PEROXISOME
    LIPID_METABOLISM["LIPID METABOLISM"] -->|"activates"| PEROXISOME
    LYSOSOME["LYSOSOME"] -->|"activates"| PEROXISOME
    BECN1["BECN1"] -->|"activates"| PEROXISOME
    NUCLEUS["NUCLEUS"] -->|"activates"| PEROXISOME
    LAMP1["LAMP1"] -->|"activates"| PEROXISOME

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (142)

Source	Relation	Type	Str
Pi3K	activates	pathway	0.50
TFEB	activates	protein	0.50
EIF2A	activates	protein	0.50
STING1	activates	protein	0.50
RICTOR	activates	gene	0.50
EIF2AK3	activates	gene	0.50
DDIT3	activates	gene	0.50
MLKL	activates	gene	0.50
STAT3	activates	gene	0.50
DEPTOR	activates	gene	0.50
RIPK1	activates	gene	0.50
FIP200	activates	gene	0.50
GABA	activates	gene	0.50
ERN1	activates	gene	0.50
MAVS	activates	gene	0.50
OPTINEURIN	activates	protein	0.50
P38 Mapk	activates	pathway	0.50
CYP1A1	activates	concept	0.50
Microrna	activates	pathway	0.50
MAP1LC3A	activates	gene	0.50
TARDBP	activates	gene	0.50
HSPB8	activates	gene	0.50
PPP3CB	activates	gene	0.50
HSPA8	activates	gene	0.50
TARDBP/TDP-43	activates	protein	0.50
amyotrophic lateral sclerosis	activates	gene	0.50
LDLR	activates	gene	0.50
Proteins	activates	protein	0.50
CARCINOMA	activates	disease	0.50
ISCHEMIC	activates	concept	0.50
Parkinson's Disease	activates	disease	0.50
PARKINSON'S	activates	concept	0.50
GRB2	activates	gene	0.50
RPTOR	activates	gene	0.50
HSP70	activates	protein	0.50
ENDOPHILIN	activates	protein	0.50
GABARAP	activates	protein	0.50
MAPK14	activates	gene	0.50
TREH	activates	gene	0.50
Sod1	activates	gene	0.50
PARKINSON	activates	gene	0.50
Neurodegenerative Diseases	activates	disease	0.50
Neuroinflammation	activates	process	0.50
inflammation	activates	pathway	0.50
EGR1	activates	protein	0.50
TRKB	activates	gene	0.50
Mitochondrial Function	activates	pathway	0.50
NBR1	activates	gene	0.50
VPS34	activates	protein	0.50
cancer	activates	disease	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning PEROXISOME in their description or question text

No additional research found