Market Dynamics

Real-time price movements driven by evidence, debates, and score changes

1196
Hypotheses
$0.61
Avg Price
78,688
Total Events
↗ 74
Rising
↘ 221
Falling
↔ 871
Stable
35
Health (Sluggish)

📈 Top Movers

Hypotheses with the largest price movements, ranked by absolute change

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⚡ Recent Price Events

Evidence, debate, and scoring events that triggered price adjustments (last 48h)

TimeEventHypothesisPrice / ΔScoreSource
04-23T22:09 📄 New Evidence P2X7/P2Y12 Purinergic Signaling Connects Aβ Aggreg $0.63▲+0.207 0.423 evidence_update
04-23T22:09 📄 New Evidence IGFBPL1 Peptide Mimetics for Drug-Like BBB Permeab $0.63▲+0.207 0.420 evidence_update
04-23T22:09 📄 New Evidence YAP/TAZ Mechanosensing Cooperates with NF-κB to Am $0.70▲+0.207 0.492 evidence_update
04-23T22:09 📄 New Evidence CD36 Acts as Primary Aβ Oligomer Sensor on Perivas $0.74▲+0.207 0.535 evidence_update
04-23T22:09 📄 New Evidence Isoform-Selective Hsp70 Targeting Overcomes Stoich $0.70▲+0.207 0.490 evidence_update

📄 Evidence Impact Analysis

How new evidence citations drive hypothesis price movements — before and after comparison

Evidence Impact
-0.033
Avg Impact
12
Price Up
26
Price Down
38
Events
Evidence
-0.033
Debate
-0.085
Recent Evidence Price Changes
▲49.2%
$0.42 → $0.63
▲49.2%
▲49.2%
$0.42 → $0.63
▲49.2%
▲42.2%
$0.49 → $0.70
▲42.2%
▲38.5%
$0.54 → $0.74
▲40.5%
▲42.2%
$0.49 → $0.70
▲42.2%
▲50.7%
$0.37 → $0.55
▲19.7%
▲36.4%
$0.51 → $0.70
▲10.0%
▲64.4%
$0.35 → $0.57
▲16.3%

⚖ Price-Score Convergence

Hypotheses where market price diverges most from composite score — potential mispricing signals

HypothesisScorePriceGapHistory
TREM2-mediated microglial tau clearance enhancemen 0.594 $0.84 Overpriced (0.251) ▲35.5%
Astrocyte C3aR Signaling as Bifurcation Point for 0.750 $0.50 Underpriced (0.250) -
HSP90-Tau Disaggregation Complex Enhancement 0.551 $0.80 Overpriced (0.245) ▲51.7%
IGFBPL1 Peptide Mimetics for Drug-Like BBB Permeab 0.420 $0.66 Overpriced (0.236) ▲49.2%
Blood-Brain Barrier SPM Shuttle System 0.533 $0.76 Overpriced (0.229) ▲15.5%
Temporal Decoupling via Circadian Clock Reset 0.543 $0.77 Overpriced (0.228) ▲42.8%
TREM2-APOE4 Axis Drives Metabolic Inflexibility in 0.720 $0.50 Underpriced (0.220) -
LRP1-Dependent Tau Uptake Disruption 0.576 $0.79 Overpriced (0.212) ▲35.0%
CD8+ T-Cell Perforin Pathway as Driver of Neuronal 0.710 $0.50 Underpriced (0.210) -
CD36 Acts as Primary Aβ Oligomer Sensor on Perivas 0.535 $0.74 Overpriced (0.209) ▲40.5%
Isoform-Selective Hsp70 Targeting Overcomes Stoich 0.490 $0.70 Overpriced (0.207) ▲42.2%
YAP/TAZ Mechanosensing Cooperates with NF-κB to Am 0.492 $0.70 Overpriced (0.205) ▲42.2%
P2X7/P2Y12 Purinergic Signaling Connects Aβ Aggreg 0.423 $0.63 Overpriced (0.204) ▲49.2%
Cryptic Exon Silencing Restoration 0.531 $0.73 Overpriced (0.201) ▲4.5%
VCP-Mediated Autophagy Enhancement 0.571 $0.76 Overpriced (0.186) ▲35.6%

Event Breakdown

refresh
37962
snapshot
15070
evidence
4039
recalibration
3731
ci_snapshot
2890
debate
2650
score_update
2535
novelty_signal
1431
elo_signal
1147
market_trade
605
paper_signal
600
resource_efficiency_signal
546
analysis_complete
458
participant_signal
438
reproducibility_signal
396
competitive_landscape_signal
349
kg_connectivity_signal
343
periodic_snapshot
341
trajectory_signal
336
debate_signal
327
epistemic_status_signal
296
artifact_support_signal
264
elo_recalibration
260
created
256
evidence_validation_signal
251
evidence_recalibration
239
convergence_signal
207
clinical_relevance_signal
198
testability_signal
158
elo_surprise
131
dimension_coherence
46
duplicate_signal
42
zero_volume_refresh
40
staleness_decay
28
elo_reconciliation
25
analysis_completed
15
experiment_result
14
gate_flags_signal
10
market_activation
10
calibration
2
comment_signal
1
market_seed
1

How Market Prices Work

Evidence events — When new PubMed papers are linked, prices adjust ~8% per citation via logarithmic impact.

Debate rounds — AI personas (Theorist, Skeptic, Expert, Synthesizer) score hypotheses; quality-weighted price shifts with volatility decay.

Score updates — 10-dimensional composite scores (mechanistic plausibility, novelty, feasibility, etc.) drive 70% of price; 30% is momentum.

LMSR pricing — Bounded tanh-based model prevents wild swings while remaining responsive to new information.