Scientific Papers

Browse 24,907 PubMed-sourced papers powering SciDEX hypotheses and knowledge graph.

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A model of saliency-based visual attention for rapid scene analysis

Laurent Itti, Christof Koch, Ernst Niebur
IEEE Transactions on Pattern Analysis and Machine Intelligence 1998 11262 citations

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

Linda Madisen, Theresa A. Zwingman, Susan M. Sunkin, Seung Wook Oh, Hatim A. Zariwala, Hong Gu, Lydia Ng, Richard D. Pal
Nature Neuroscience 2009 7285 citations PMID: 20023653

Ultrasensitive fluorescent proteins for imaging neuronal activity

Tsai‐Wen Chen, Trevor J. Wardill, Yi Sun, Stefan R. Pulver, Sabine L. Renninger, Amy Baohan et al.
Nature 2013 7019 citations PMID: 23868258

A general framework for estimating the relative pathogenicity of human genetic variants

Martin Kircher, Daniela Witten, Preti Jain, Brian J. O’Roak, Gregory M. Cooper et al.
Nature Genetics 2014 6496 citations PMID: 24487276

Genome-wide atlas of gene expression in the adult mouse brain

Lein, Hawrylycz, Ao, Ayres, Bensinger et al.
Nature 2006 5915 citations PMID: 17151600

Computational modelling of visual attention

Laurent Itti, Christof Koch
Nature reviews. Neuroscience 2001 4721 citations PMID: 11256080

The single-cell transcriptional landscape of mammalian organogenesis

Junyue Cao, Malte Spielmann, Xiaojie Qiu, Xingfan Huang, Daniel M. Ibrahim et al.
Nature 2019 4616 citations PMID: 30787437

Next-generation DNA sequencing

Jay Shendure, Hanlee P. Ji
Nature Biotechnology 2008 4484 citations PMID: 18846087

Think you have Solved Question Answering? Try ARC, the AI2 Reasoning Challenge

Peter Clark, Isaac Cowhey, Oren Etzioni, Tushar Khot, Ashish Sabharwal, Carissa Schoenick, Oyvind Tafjord
arXiv.org 2018 4422 citations

The origin of extracellular fields and currents — EEG, ECoG, LFP and spikes

György Buzsáki, Costas A. Anastassiou, Christof Koch
Nature reviews. Neuroscience 2012 4368 citations PMID: 22595786

CADD: predicting the deleteriousness of variants throughout the human genome

Philipp Rentzsch, Daniela Witten, Gregory M. Cooper, Jay Shendure, Martin Kircher
Nucleic Acids Research 2018 3807 citations PMID: 30371827

Shifts in Selective Visual Attention: Towards the Underlying Neural Circuitry

Christof Koch, Shimon Ullman
1987 3771 citations PMID: 3836989

Graph-Based Visual Saliency

Jonathan Harel, Christof Koch, Pietro Perona
The MIT Press eBooks 2007 3468 citations

Self-Refine: Iterative Refinement with Self-Feedback

Aman Madaan, Niket Tandon, Prakhar Gupta, Skyler Hallinan, Luyu Gao, Sarah Wiegreffe, Uri Alon, Nouha Dziri et al.
Neural Information Processing Systems 2023 3244 citations

An anatomically comprehensive atlas of the adult human brain transcriptome

Michael Hawrylycz, Ed S. Lein, Angela Guillozet-Bongaarts, Elaine Shen, Lydia Ng, Jeremy A. Miller, Louie N. van de Lage
Nature 2012 3231 citations PMID: 22996553

A saliency-based search mechanism for overt and covert shifts of visual attention

L. Itti, Christof Koch
Vision Research 2000 3177 citations PMID: 10788654

A mesoscale connectome of the mouse brain

Seung Wook Oh, Julie A. Harris, Lydia Ng, Brent Winslow, Nicholas Cain, Ştefan Mihalaş, Quanxin Wang, Chris Lau et al.
Nature 2014 2843 citations PMID: 24695228

The contribution of de novo coding mutations to autism spectrum disorder

Ivan Iossifov, Brian J. O’Roak, Stephan Sanders, Michael Ronemus, Niklas Krumm et al.
Nature 2014 2765 citations PMID: 25363768

Widespread transcription at neuronal activity-regulated enhancers.

Kim, Tae-Kyung, Hemberg, Martin, Gray, Jesse M, Costa, Allen M, Bear, Daniel M, Wu, Jing, Harmin, David A, Laptewicz, Mi
Nature 2010 2505 citations PMID: 20393465

The complete genome sequence of a Neanderthal from the Altai Mountains

Prüfer, Racimo, Patterson, Jay, Sankararaman et al.
Nature 2013 2382 citations PMID: 24352235

Fully integrated silicon probes for high-density recording of neural activity

James J. Jun, Nicholas A. Steinmetz, Joshua H. Siegle, Daniel J. Denman, Marius Bauža, Brian Barbarits, Albert K. Lee, C
Nature 2017 2349 citations PMID: 29120427

Can a Suit of Armor Conduct Electricity? A New Dataset for Open Book Question Answering

Todor Mihaylov, Peter Clark, Tushar Khot, Ashish Sabharwal
Conference on Empirical Methods in Natural Language Processing 2018 2315 citations

Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations

Brian J. O’Roak, Laura Vives, Santhosh Girirajan, Emre Karakoç, Niklas Krumm et al.
Nature 2012 2216 citations PMID: 22495309

Learn to Explain: Multimodal Reasoning via Thought Chains for Science Question Answering

Pan Lu, Swaroop Mishra, Tony Xia, Liang Qiu, Kai-Wei Chang, Song-Chun Zhu, Oyvind Tafjord, Peter Clark et al.
Neural Information Processing Systems 2022 2200 citations

Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection

E. John Wherry; Sang‐Jun Ha; Susan M. Kaech; W. Nicholas Haining; Surojit Sarkar; Vandana Kalia; Shruti Subramaniam; Jos
Immunity 2007 2106 citations PMID: 17950003

A High-Coverage Genome Sequence from an Archaic Denisovan Individual

Matthias Meyer, Martin Kircher, Marie-Theres Gansauge, Heng Li, Fernando Racimo et al.
Science 2012 2092 citations PMID: 22936568

Biophysics of Computation

Christof Koch
Oxford University Press eBooks 1998 2066 citations

Targeted capture and massively parallel sequencing of 12 human exomes

Sarah Ng, Emily H. Turner, Peggy D. Robertson, Steven Flygare, Abigail W. Bigham et al.
Nature 2009 2031 citations PMID: 19684571

Invariant visual representation by single neurons in the human brain

Rodrigo Quian Quiroga, Leila Reddy, Gabriel Kreiman, Christof Koch, Itzhak Fried
Nature 2005 2024 citations PMID: 15973409

Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators

Lin Tian, Samuel Andrew Hires, Tianyi Mao, Daniel Huber, M Eugenia Chiappe, Sreekanth H. Chalasani et al.
Nature Methods 2009 2012 citations PMID: 19898485

Experience-dependent structural synaptic plasticity in the mammalian brain

Anthony Holtmaat, Karel Svoboda
Nature reviews. Neuroscience 2009 1943 citations PMID: 19693029

Shared and distinct transcriptomic cell types across neocortical areas

Bosiljka Tasic, Zizhen Yao, Lucas T. Graybuck, Kimberly A. Smith, Thuc Nghi Nguyen, Darren Bertagnolli, Jeff Goldy, Emma
Nature 2018 1942 citations PMID: 30382198

Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex

Joshua T. Trachtenberg, Brian E. Chen, Graham Knott, Guoping Feng, Joshua R. Sanes, Egbert Welker et al.
Nature 2002 1942 citations PMID: 12490942

Adult mouse cortical cell taxonomy revealed by single cell transcriptomics

Bosiljka Tasic, Vilas Menon, Thuc Nghi Nguyen, Tae Kyung Kim, Tim Jarsky, Zizhen Yao, Boaz P. Levi, Lucas T. Gray et al.
Nature Neuroscience 2016 1937 citations PMID: 26727548

Exome sequencing identifies the cause of a mendelian disorder

Sarah Ng, Kati J. Buckingham, Choli Lee, Abigail W. Bigham, Holly K. Tabor et al.
Nature Genetics 2009 1935 citations PMID: 19915526

Direct observation of kinesin stepping by optical trapping interferometry

Karel Svoboda, Christoph F. Schmidt, Bruce J. Schnapp, Steven M. Block
Nature 1993 1913 citations PMID: 8413650

Conserved cell types with divergent features in human versus mouse cortex

Rebecca D. Hodge, Trygve E. Bakken, Jeremy A. Miller, Kimberly A. Smith, Eliza Barkan, Lucas T. Graybuck, Jennie Close,
Nature 2019 1910 citations PMID: 31435019

An efficient targeted nuclease strategy for high-resolution mapping of DNA binding sites

P. Skene, S. Henikoff
bioRxiv 2016 1872 citations PMID: 28079019

Effector and memory T-cell differentiation: implications for vaccine development

Susan M. Kaech; E. John Wherry; Rafi Ahmed
Nature reviews. Immunology 2002 1846 citations PMID: 12001996

Lineage relationship and protective immunity of memory CD8 T cell subsets

E. John Wherry; Volker Teichgräber; Todd C. Becker; David Masopust; Susan M. Kaech; Rustom Antia; Ulrich H. von Andrian;
Nature Immunology 2003 1840 citations PMID: 12563257
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