Atlas

Living Knowledge Graph — 714,225 edges connecting 50 entities

Full Graph Wiki Trials
714,225
KG Edges
17,576
Wiki Pages
24,907
Papers
1,222
Hypotheses
47,851
Entities

Edge Types

pubmed cooccurrence
233,645
pubmed abstract nlp
89,658
pubmed v5 extraction
46,637
cooccurrence
44,675
pubmed v4 extraction
32,427
co occurrence
28,959
pubmed extraction
25,985
pubmed cooccurrence v3
24,809
association
13,650
pubmed v12 nlp
11,254
pubmed abstract top50 v3
9,920
dataset row
9,358

Relation Types

activates
139,587
associated_with
104,293
regulates
73,957
inhibits
57,949
interacts_with
51,700
expressed_in
45,725
therapeutic_target
44,935
causes
23,843
co_discussed
23,598
contributes_to
16,962

Top Entities by Connections

Als 9,929.0
disease
ALZHEIMER 8,445.0
gene
AUTOPHAGY 6,371.0
gene
Cancer 6,324.0
disease
APOPTOSIS 6,192.0
gene
INFLAMMATION 6,026.0
gene
Alzheimer 5,871.0
disease
ALZHEIMER'S DISEASE 5,768.0
gene
Neurodegeneration 5,718.0
disease
MTOR 5,587.0
gene
ALS 5,568.0
disease
Ms 5,498.0
disease
PARKINSON 5,496.0
gene
AKT 5,495.0
gene
Inflammation 5,485.0
disease
TNF 5,381.0
gene
NEURODEGENERATION 5,281.0
gene
PI3K 4,960.0
gene
Tumor 4,713.0
disease
APOE 4,676.0
gene
Aging 4,612.0
disease
Neuron 4,527.0
cell type
AMYLOID 4,497.0
gene
BDNF 4,491.0
gene
APP 4,347.0
gene
Autophagy 4,247.0
pathway
TAU 4,216.0
gene
AGING 4,216.0
gene
Apoptosis 4,178.0
pathway
NLRP3 4,174.0
gene
OXIDATIVE STRESS 4,165.0
gene
MICROGLIA 4,112.0
gene
NEURODEGENERATIVE DISEASES 4,050.0
gene
ROS 3,973.0
gene
AMPK 3,830.0
gene
Parkinson 3,754.0
disease
CYTOKINES 3,744.0
gene
SQSTM1 3,673.0
gene
NEUROINFLAMMATION 3,640.0
gene
DEMENTIA 3,611.0
gene
MITOCHONDRIA 3,594.0
gene
PINK1 3,466.0
gene
TREM2 3,466.0
gene
PARKINSON'S DISEASE 3,441.0
gene
STAT3 3,354.0
gene
Oxidative Stress 3,321.0
pathway
UBIQUITIN 3,301.0
gene
Neuroinflammation 3,296.0
disease
NRF2 3,205.0
gene
MAPK 3,140.0
gene

Recent Edges

Source Relation Target Date
cortex exhibits myelin dysfunction
hippocampus vulnerability_locus_for Alzheimer disease
SOX10 regulates OPC differentiation
CDKN2A biomarker_for hippocampal neurodegeneration
PLP1 associated_with myelin dysfunction
MBP associated_with Alzheimer disease
ELF2 downregulated_in brain aging
ELF2 regulates OPC epigenetic drift
40624017 induces protein aggregation
40624017 is located within the ER and interacts with ceramide synthase 2 (CERS2) to limit emp1
18164103 activates Hsv-1
18164103 is transported to nucleus via Hsv-1
18164103 modifies HSV-1 Infectivity
18164103 binds to Hsv-1
34433968 bind to and become trapped by low_density_lipoproteins
34433968 confers atheroprotection by binding to APRIL
34433968 limits atherosclerosis
34433968 limits APRIL
31818979 may instruct CNS niche
31818979 acquire CNS-infiltrating macrophages