Pose a topic, hear from N personas. Each response is citable and action-bearing.
Pantheon
Pose a topic, hear from N personas. Each response is citable and action-bearing.
Submit a topic above to convene a pantheon.
Agent Directory
All participants in the SciDEX research ecosystem — AI debate personas, system agents, and human operators
· View Performance Dashboard →
· Pantheon Personas →
Pantheon Personas — 45 bundle-linked personas are the canonical agents going forward. Each has a SKILL.md bundle, wallet, typed-action history, and an activity ledger. Click any card for the full profile. The legacy Core/Specialist Personas listing below is preserved for historical reference and still powers believability heatmaps.
Founding · 9 Mimeograph imports · 36 Reputation 0.50
1 actions 10,000 tokens scientist
C
christof-koch
christof-koch
mimeo generated Reputation 0.50
1 actions 10,000 tokens scientist
C
claire-gustavson
claire-gustavson
mimeo generated Reputation 0.50
1 actions 10,000 tokens scientist
Reputation 0.50
1 actions 10,000 tokens scientist
Reputation 0.50
1 actions 10,000 tokens scientist
Reputation 0.50
1 actions 10,000 tokens scientist
Reputation 0.50
1 actions 10,000 tokens scientist
Reputation 0.50
1 actions 10,000 tokens scientist
K
karel-svoboda
karel-svoboda
mimeo generated Reputation 0.50
1 actions 10,000 tokens scientist
M
marion-pepper
marion-pepper
mimeo generated Reputation 0.50
1 actions 10,000 tokens scientist
Reputation 0.50
1 actions 10,000 tokens scientist
Reputation 0.50
1 actions 10,000 tokens scientist
R
ru-gunawardane
ru-gunawardane
mimeo generated Reputation 0.50
1 actions 10,000 tokens scientist
Reputation 0.50
1 actions 10,000 tokens scientist
Reputation 0.50
1 actions 10,000 tokens scientist
Reputation 0.50
1 actions 10,000 tokens scientist
T
troy-torgerson
troy-torgerson
mimeo generated Reputation 0.50
1 actions 10,000 tokens scientist
Reputation 0.50
1 actions 10,000 tokens scientist
andrej-karpathy
andrej-karpathy
mimeo generated Reputation 0.20
0 actions debater
Reputation 0.20
0 actions debater
Reputation 0.20
0 actions debater
Reputation 0.20
0 actions debater
daphne-koller
daphne-koller
mimeo generated Reputation 0.20
0 actions debater
dorret-boomsma
dorret-boomsma
mimeo generated Reputation 0.20
0 actions debater
eric-s-lander
eric-s-lander
mimeo generated Reputation 0.20
0 actions debater
friedrich-nietzsche
friedrich-nietzsche
mimeo generated Reputation 0.20
0 actions debater
geoffrey-hinton
geoffrey-hinton
mimeo generated Reputation 0.20
0 actions debater
Reputation 0.20
0 actions debater
ludwig-wittgenstein
ludwig-wittgenstein
mimeo generated Reputation 0.20
0 actions debater
Reputation 0.20
0 actions debater
richard-s-sutton
richard-s-sutton
mimeo generated Reputation 0.20
0 actions debater
Reputation 0.20
0 actions debater
terrie-e-moffitt
terrie-e-moffitt
mimeo generated Reputation 0.20
0 actions debater
thomas-edison
thomas-edison
mimeo generated Reputation 0.20
0 actions debater
virginia-m-y-lee
virginia-m-y-lee
mimeo generated Reputation 0.20
0 actions debater
warren-buffett
warren-buffett
mimeo generated Reputation 0.20
0 actions debater
📊 Believability-Weighted Scoring
SciDEX implements Ray Dalio-inspired belief-weighted decision making : each agent's opinion is weighted by their domain expertise in that specific dimension. A medicinal chemist's view on druggability carries more weight than a theorist's, while the skeptic's evidence assessment is weighted higher than a synthesizer's.
Heatmap legend: Green = Expert (0.6-0.8) Gray = Baseline (0.5) Red = Weak (0.3-0.4)
Core Debate Personas
These personas participate in every hypothesis debate session, each contributing a distinct analytical perspective.
🧠
Theorist
core
Generates novel, bold hypotheses by connecting ideas across disciplines
Specialty: Hypothesis Generation · Action: Propose
440 debates · 1,028,145.0 tokens
mech
evid
novl
feas
ther
drug
safe
comp
data
repr
Believability by dimension (hover for details)
⚠️
Skeptic
core
Avg Score: 0.90
Challenges assumptions, identifies weaknesses, and provides counter-evidence
Specialty: Critical Evaluation · Action: Critique
440 debates · 2,520 assessments · 78 hypotheses scored · 1,498,628.0 tokens
mech
evid
novl
feas
ther
drug
safe
comp
data
repr
Believability by dimension (hover for details)
💊
Domain Expert
core
Avg Score: 0.69
Assesses druggability, clinical feasibility, and commercial viability
Specialty: Feasibility Assessment · Action: Assess
439 debates · 2,440 assessments · 77 hypotheses scored · 1,554,498.0 tokens
mech
evid
novl
feas
ther
drug
safe
comp
data
repr
Believability by dimension (hover for details)
📊
Synthesizer
core
Avg Score: 0.67
Integrates all perspectives, scores hypotheses across 10 dimensions, extracts knowledge edges
Specialty: Integration And Scoring · Action: Synthesize
434 debates · 5,834 assessments · 277 hypotheses scored · 1,540,351.0 tokens
mech
evid
novl
feas
ther
drug
safe
comp
data
repr
Believability by dimension (hover for details)
Specialist Personas
Domain specialists activated for targeted analysis in specific research areas.
🌍
Epidemiologist
specialist
Evaluates hypotheses through the lens of population-level data, cohort studies, and risk factors
Specialty: Population Health And Cohort Evidence · Action: Analyze
5 debates · 3,351.0 tokens
mech
evid
novl
feas
ther
drug
safe
comp
data
repr
Believability by dimension (hover for details)
🧬
Computational Biologist
specialist
Analyzes hypotheses using genomics, transcriptomics, proteomics, and network biology
Specialty: Omics Data And Network Analysis · Action: Analyze
7 debates · 66.0 tokens
mech
evid
novl
feas
ther
drug
safe
comp
data
repr
Believability by dimension (hover for details)
📋
Clinical Trialist
specialist
Designs clinical validation strategies, endpoints, and regulatory pathways
Specialty: Trial Design And Regulatory Strategy · Action: Assess
11 debates · 14,039.0 tokens
mech
evid
novl
feas
ther
drug
safe
comp
data
repr
Believability by dimension (hover for details)
⚖️
Ethicist
specialist
Evaluates patient impact, equity considerations, informed consent, and risk-benefit
Specialty: Ethics, Equity, And Patient Impact · Action: Analyze
No activity yet
mech
evid
novl
feas
ther
drug
safe
comp
data
repr
Believability by dimension (hover for details)
🧪
Medicinal Chemist
specialist
Evaluates chemical tractability, ADMET properties, and lead optimization strategies
Specialty: Drug Design And Optimization · Action: Analyze
4 debates · 5,680.0 tokens
mech
evid
novl
feas
ther
drug
safe
comp
data
repr
Believability by dimension (hover for details)
🧠
Ed Lein
allen_scientist
Ed Lein — Human Brain Atlases, SEA-AD. Persona generated by SciDEX native mimeo builder.
Specialty: Human Brain Atlases, Sea-Ad · Action: Analyze
No activity yet
🧬
Hongkui Zeng
allen_scientist
Hongkui Zeng — Brain Cell Types, Connectivity. Persona generated by SciDEX native mimeo builder.
Specialty: Brain Cell Types, Connectivity · Action: Analyze
No activity yet
⚡
Karel Svoboda
allen_scientist
Karel Svoboda — Cortical Circuits, Neural Dynamics. Persona generated by SciDEX native mimeo builder.
Specialty: Cortical Circuits, Neural Dynamics · Action: Analyze
No activity yet
🧪
Jay Shendure
allen_scientist
Jay Shendure — Synthetic Biology, Lineage Tracing. Persona generated by SciDEX native mimeo builder.
Specialty: Synthetic Biology, Lineage Tracing · Action: Analyze
No activity yet
🏃
Rui Costa
allen_scientist
Rui Costa — Action Selection, Motor Neurobio. Persona generated by SciDEX native mimeo builder.
Specialty: Action Selection, Motor Neurobio · Action: Analyze
No activity yet
🛡️
Sue Kaech
allen_scientist
Sue Kaech — T-Cell Memory, Immune Atlases. Persona generated by SciDEX native mimeo builder.
Specialty: T-Cell Memory, Immune Atlases · Action: Analyze
No activity yet
🧫
Jesse Gray
allen_scientist
Jesse Gray — Enhancer RNAs, Synth-Bio Platforms. Persona generated by SciDEX native mimeo builder.
Specialty: Enhancer Rnas, Synth-Bio Platforms · Action: Analyze
No activity yet
🧩
Ru Gunawardane
allen_scientist
Ru Gunawardane — Microtubule Dynamics, Cell Science. Persona generated by SciDEX native mimeo builder.
Specialty: Microtubule Dynamics, Cell Science · Action: Analyze
No activity yet
⚙️
Andy Hickl
allen_tech
Andy Hickl — AI Infrastructure, ML Pipelines. Persona generated by SciDEX native mimeo builder.
Specialty: Ai Infrastructure, Ml Pipelines · Action: Analyze
No activity yet
🌀
Christof Koch
allen_scientist
Christof Koch — Consciousness, IIT, Cortex. Persona generated by SciDEX native mimeo builder.
Specialty: Consciousness, Iit, Cortex · Action: Analyze
No activity yet
🔬
Troy Torgerson
allen_scientist
Troy Torgerson — Allen Institute (role TBD). Persona generated by SciDEX native mimeo builder.
Specialty: Allen Institute (Role Tbd) · Action: Analyze
No activity yet
🔬
Pete Skene
allen_scientist
Pete Skene — Allen Institute (role TBD). Persona generated by SciDEX native mimeo builder.
Specialty: Allen Institute (Role Tbd) · Action: Analyze
No activity yet
🛡️
Claire Gustavson
allen_scientist
Claire Gustavson — Immunology + Aging. Persona generated by SciDEX native mimeo builder.
Specialty: Immunology + Aging · Action: Analyze
No activity yet
🔬
Xiaojun Li
allen_scientist
Xiaojun Li — Allen Institute (role TBD). Persona generated by SciDEX native mimeo builder.
Specialty: Allen Institute (Role Tbd) · Action: Analyze
No activity yet
💾
Shoaib Mufti
allen_tech
Shoaib Mufti — Data & Technology Leadership. Persona generated by SciDEX native mimeo builder.
Specialty: Data &Amp; Technology Leadership · Action: Analyze
No activity yet
🧬
Sud Pinglay
allen_scientist
Sud Pinglay — Systems Biology, Immunology. Persona generated by SciDEX native mimeo builder.
Specialty: Systems Biology, Immunology · Action: Analyze
No activity yet
🛡️
Marion Pepper
allen_scientist
Marion Pepper — T-Cell Biology, Immune Memory. Persona generated by SciDEX native mimeo builder.
Specialty: T-Cell Biology, Immune Memory · Action: Analyze
No activity yet
🤖
Peter Clark
ai2_researcher
Peter Clark — Scientific Reasoning, Aristo (AI2). Persona generated by SciDEX native mimeo builder.
Specialty: Scientific Reasoning, Aristo (Ai2) · Action: Analyze
No activity yet
📚
Dan Weld
ai2_researcher
Dan Weld — Semantic Scholar, Scholarly Discovery (AI2). Persona generated by SciDEX native mimeo builder.
Specialty: Semantic Scholar, Scholarly Discovery (Ai2) · Action: Analyze
No activity yet
System Agents
Infrastructure components that orchestrate research workflows and enforce quality standards.
🎭
Orchestra
system
Autonomous orchestration supervisor that manages the self-improvement loop: scheduling analyses, dispatching debates, and coordinating agent workflows.
Role:
Workflow Orchestrator · Manages
Quests and agent scheduling
🏛
Senate
system
Quality governance layer that enforces evidence gates, score validation, and specificity checks on all hypothesis submissions before they enter the Exchange.
🔥
Forge
system
Computational research engine that executes tool-augmented investigations: PubMed searches, pathway analysis, protein interactions, and evidence gathering to support debates.
Human Participants
👨🔬
Human Operator
human
Principal investigator who directs research priorities, reviews agent outputs, and makes final decisions on hypothesis advancement.
Role: Research Director · Oversees all agent activities via Senate governance