gene

ATG

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ATG: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

1972Connections

0Hypotheses

0Analyses

50Outgoing

50Incoming

0Experiments

0Debates

Summary

ATG is a gene implicated in neurodegeneration research. Key relationships include: associated with, interacts with, activates. Associated with AD, ADH, ALI. Connected to 1181 entities in the SciDEX knowledge graph.

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🧬 Gene Info

Gene Symbol	ATG
Pathways	Autophagy
GeneCards	ATG
Human Protein Atlas	ATG
Associated Diseases	AD, ADH, Aging, ALI, Als, Alzheimer
Known Drugs/Compounds	rapamycin
Interactions	ABCD3, ACAT1, ACETYL-COA, ACOX1, ACTB, Actin
KG Connections	1972 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (20)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    ATG["ATG"] -->|"regulates"| AUTOPHAGY["AUTOPHAGY"]
    ATG["ATG"] -->|"regulates"| Ischemia["Ischemia"]
    ATG["ATG"] -->|"activates"| Metabolic_Syndrome["Metabolic Syndrome"]
    ATG["ATG"] -->|"regulates"| Ms["Ms"]
    ATG["ATG"] -->|"interacts"| Dementia["Dementia"]
    ATG["ATG"] -->|"interacts"| Alzheimer["Alzheimer"]
    PIK3C3["PIK3C3"] -->|"regulates"| ATG["ATG"]
    RPS6["RPS6"] -->|"regulates"| ATG["ATG"]
    MAP1LC3B["MAP1LC3B"] -->|"regulates"| ATG["ATG"]
    MTOR["MTOR"] -->|"regulates"| ATG["ATG"]
    style ATG fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (1407)

Target	Relation	Type	Str
LC3	interacts_with	gene	1.00
Autophagy	activates	pathway	1.00
Tumor	activates	disease	1.00
AUTOPHAGY	regulates	pathway	1.00
Autophagy	regulates	pathway	1.00
Autophagy	associated_with	pathway	1.00
Als	associated_with	disease	1.00
AUTOPHAGY	activates	gene	1.00
AUTOPHAGY	associated_with	gene	1.00
Autophagy	interacts_with	pathway	1.00
AUTOPHAGY	interacts_with	gene	1.00
MTOR	associated_with	gene	1.00
ROS	associated_with	gene	1.00
Als	regulates	disease	0.95
Tumor	associated_with	disease	0.95
Als	activates	disease	0.95
Non-Alcoholic Fatty Liver Disease	involved_in	disease	0.95
Autophagy	involved_in	process	0.95
Inflammation	regulates	disease	0.95
ULK1	regulates	gene	0.90
neural stem cells	activates	cell_type	0.90
RAS	activates	gene	0.90
neural stem cells	regulates	cell_type	0.90
oxidative stress response	participates_in	pathway	0.90
autophagy-related pathways	regulates	pathway	0.90
GENES	regulates	gene	0.90
ALS	associated_with	gene	0.90
Mtor	associated_with	pathway	0.90
INFLAMMATION	regulates	gene	0.90
Als	interacts_with	disease	0.85
Cancer	regulates	disease	0.85
Inflammation	activates	disease	0.85
Als	inhibits	disease	0.85
Inflammation	inhibits	disease	0.85
Cancer	associated_with	disease	0.85
Carcinoma	associated_with	disease	0.85
Cancer	activates	disease	0.85
PIK3C3	activates	gene	0.80
ATG5	component_of	gene	0.80
ATG8	component_of	gene	0.80
RAB7A	activates	gene	0.80
STX17	regulates	gene	0.80
ATG16	component_of	gene	0.80
CTSD	activates	gene	0.80
ATG14L	component_of	gene	0.80
LAMP1	activates	gene	0.80
TFEB	regulates	gene	0.80
GABA	regulates	gene	0.80
ATG29	component_of	gene	0.80
RNA	regulates	gene	0.80

Incoming (565)

Source	Relation	Type	Str
AUTOPHAGY	associated_with	gene	1.00
BECN1	associated_with	gene	1.00
SQSTM1	associated_with	gene	1.00
Autophagosome Formation	associated_with	process	0.90
rapamycin	targets	drug	0.90
C9ORF72	associated_with	gene	0.90
FOXO1	regulates	gene	0.80
AMBRA1	activates	gene	0.80
GPX4	associated_with	gene	0.80
P62	associated_with	gene	0.80
ELAVL1	associated_with	gene	0.70
TFEB	associated_with	gene	0.70
kinase-mediated phosphorylation	regulates	process	0.70
TLR4	regulates	protein	0.70
AUTOPHAGY	regulates	gene	0.70
small-molecule kinase inhibitors	regulates	drug	0.70
AUTOPHAGY	activates	gene	0.70
PARKINSON	associated_with	gene	0.70
APC	activates	gene	0.70
protein kinases	regulates	protein	0.70
UBIQUITIN	interacts_with	gene	0.70
TGFB1	associated_with	gene	0.70
LC3	associated_with	gene	0.70
COL1A1	associated_with	gene	0.70
UBIQUITIN	activates	gene	0.70
ULK1	associated_with	gene	0.70
MAP1LC3	associated_with	gene	0.70
RB1	associated_with	gene	0.70
RAN	associated_with	gene	0.70
GFP	associated_with	gene	0.70
AR	activates	gene	0.70
GENES	activates	gene	0.70
PIK3C3	associated_with	gene	0.70
OPTN	associated_with	gene	0.70
LYSOSOME	regulates	gene	0.70
GABARAP	associated_with	gene	0.70
GBA	interacts_with	gene	0.60
HIF1A	interacts_with	gene	0.60
OPTN	interacts_with	gene	0.60
BNIP3L	interacts_with	gene	0.60
PRKN	interacts_with	gene	0.60
MAP1LC3B	interacts_with	gene	0.60
DDIT3	interacts_with	gene	0.60
ATM	interacts_with	gene	0.60
BNIP3	interacts_with	gene	0.60
LC3B	interacts_with	gene	0.60
DRP1	interacts_with	gene	0.60
SESN2	interacts_with	gene	0.60
RB1	interacts_with	gene	0.60
WIPI2	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

ATG

Understanding Entity Pages

Summary

Wiki Pages (20)

ATG7 Protein — Autophagy-Related Protein 7

ATG14 Protein

ATG10 Gene

ATG4D Gene

ATG4B — Autophagy Related 4B Cysteine Peptidase

ATG17A

ATG9L1 (Autophagy Related 9 Like 1)

ATG7 Protein

ATG4C Gene

ATG5 — Autophagy Related 5

ATG3 Gene

ATG9A Gene

ATG17 Gene

ATG13 — Autophagy Related 13

ATG4B Protein — Autophagy Related 4B

ATG14 Protein

ATG12 — Autophagy Related 12

ATG9A Protein

ATG16L2 Gene

ATG3 Protein