RAN

Understanding Entity Pages

This page aggregates everything SciDEX knows about RAN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

RAN is a gene implicated in neurodegeneration research. Key relationships include: associated with, therapeutic target, activates. Associated with Aging, Als, Amyotrophic Lateral Sclerosis. Connected to 73 entities in the SciDEX knowledge graph.

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graph TD
    RAN["RAN"]
    Als{"Als"}
    RAN -->|"associated with"| Als
    Ms{"Ms"}
    RAN -->|"interacts with"| Ms
    Amyotrophic_Lateral_Sclerosis{"Amyotrophic Lateral Sclerosis"}
    RAN -->|"interacts with"| Amyotrophic_Lateral_Sclerosis
    Dementia{"Dementia"}
    RAN -->|"associated with"| Dementia
    Ataxia{"Ataxia"}
    RAN -->|"associated with"| Ataxia
    Huntington{"Huntington"}
    RAN -->|"associated with"| Huntington
    RAN -->|"associated with"| Ms
    RAN -->|"associated with"| Amyotrophic_Lateral_Sclerosis
    Inflammation{"Inflammation"}
    RAN -->|"inhibits"| Inflammation
    RAN -->|"regulates"| Als
    Neuroinflammation{"Neuroinflammation"}
    RAN -->|"inhibits"| Neuroinflammation
    RAN -->|"inhibits"| Amyotrophic_Lateral_Sclerosis
    C9ORF72["C9ORF72"]
    C9ORF72 -->|"interacts with"| RAN
    C9ORF72 -->|"associated with"| RAN
    P62["P62"]
    P62 -->|"inhibits"| RAN
    NOTCH3["NOTCH3"]
    NOTCH3 -->|"associated with"| RAN
    EIF2A["EIF2A"]
    EIF2A -->|"inhibits"| RAN
    NEURODEGENERATIVE_DISEASES["NEURODEGENERATIVE DISEASES"]
    NEURODEGENERATIVE_DISEASES -->|"associated with"| RAN
    EIF2A -->|"activates"| RAN
    ATG["ATG"]
    ATG -->|"associated with"| RAN
    FTLD["FTLD"]
    FTLD -->|"contributes to"| RAN
    NEURODEGENERATIVE_DISORDERS["NEURODEGENERATIVE DISORDERS"]
    NEURODEGENERATIVE_DISORDERS -->|"associated with"| RAN
    style RAN fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

No debates reference this entity