gene 1,613 words KG: ent-gene-01e81bf7
Contents

ATG9A Gene

🧬 Gene Info
Gene SymbolATG9A
AliasesATG9A protein
Chromosome2p24.1
Protein FamilyATG9 family
FunctionMembrane Source: Provides lipids for phagophore expansion
Subcellular LocalizationTrans-Golgi network, Endosomes, Plasma membrane, Autophagosomes
Molecular Weight139 kDa
Amino Acids790 aa
PathwaysAutophagy, Mitochondrial Function, Mitophagy, Nf-Κb, Stem Cell
UniProt IDQ7Z418
GeneCardsATG9A
Human Protein AtlasATG9A
Trans-Golgi network (TGN)Primary reservoir for ATG9A under basal conditions [10]
EndosomesATG9A-positive endosomes deliver membrane to autophagosomes [11]
Plasma membraneConstitutive endocytosis and recycling [12]
Associated DiseasesMs
InteractionsAND, ARAF, ATG, ATG101, ATG12, ATG13
KG Connections174 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (4)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67
Quantum Coherence Disruption in Cellular Communication
Score: 0.63

Related Analyses (5)

Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (12)

Apoptosis in Neurodegeneration
entity · KG edge: protects_against
APEX2 Gene
gene · KG edge: regulates
ARAF Gene
gene · KG edge: activates
atg101
gene · KG edge: interacts_with
ATG12 — Autophagy Related 12
gene · KG edge: activates

Knowledge Graph (4 edges)

h-2c11c690e8 targets ent-gene-01e81bf7
ent-gene-01e81bf7 targeted_by h-2c11c690e8
ent-gene-01e81bf7 data_in benchmark_ot_ad_answer_key:ATG9A
benchmark_ot_ad_answer_key:ATG9A data_in ent-gene-01e81bf7

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