concept

NEURAL STEM CELLS

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NEURAL STEM CELLS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

912Connections

0Hypotheses

0Analyses

14Outgoing

50Incoming

0Experiments

0Debates

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💡 Concept Info

Name	NEURAL STEM CELLS
Key Genes/Proteins	AQP4, BDNF, MYC, TET2
Related Diseases	AUTOPHAGY, NEUROGENESIS
Related Pathways	WNT PATHWAY, WNT SIGNALING

Pathway Diagram

graph TD
    NEURAL_STEM_CELLS["NEURAL STEM CELLS"]
    NEURAL_STEM_CELLS -->|"treats"| Neurological_Disorders["Neurological Disorders"]
    NEURAL_STEM_CELLS -->|"treats"| Multiple_Sclerosis["Multiple Sclerosis"]
    NEURAL_STEM_CELLS -->|"modulates"| Inflammation["Inflammation"]
    NEURAL_STEM_CELLS -->|"treats"| Alzheimer_S_Disease["Alzheimer'S Disease"]
    NEURAL_STEM_CELLS -->|"treats"| Parkinson_S_Disease["Parkinson'S Disease"]
    NEURAL_STEM_CELLS -->|"treats"| Amyotrophic_Lateral_Sclerosis["Amyotrophic Lateral Sclerosis"]
    SOX2["SOX2"] -->|"regulates"| NEURAL_STEM_CELLS
    FIP200["FIP200"] -->|"regulates"| NEURAL_STEM_CELLS
    TAX1BP1["TAX1BP1"] -->|"regulates"| NEURAL_STEM_CELLS
    PIEZO1["PIEZO1"] -->|"regulates"| NEURAL_STEM_CELLS
    TET2["TET2"] -->|"activates"| NEURAL_STEM_CELLS
    CHI3L1["CHI3L1"] -->|"inhibits"| NEURAL_STEM_CELLS
    autophagic_cell_death["autophagic cell death"] -->|"causes"| NEURAL_STEM_CELLS
    AQP4["AQP4"] -->|"inhibits"| NEURAL_STEM_CELLS

Outgoing (14)

Target	Relation	Type	Str
Adult Neurogenesis	involved_in	process	0.95
Neuronal Markers	associated_with	biomarker	0.85
Neurological Disorders	treats	disease	0.82
Inflammation	modulates	process	0.80
Tissue Damage	associated_with	phenotype	0.80
Multiple Sclerosis	treats	disease	0.80
Alzheimer'S Disease	treats	disease	0.75
Parkinson'S Disease	treats	disease	0.75
Amyotrophic Lateral Sclerosis	treats	disease	0.75
SPINAL CORD	associated_with	brain_region	0.50
WNT PATHWAY	associated_with	pathway	0.50
DENTATE GYRUS	associated_with	brain_region	0.50
WNT SIGNALING	associated_with	pathway	0.50
CURCUMIN	associated_with	drug	0.45

Incoming (898)

Source	Relation	Type	Str
SOX2	regulates	gene	0.92
HDAC3	inhibits	gene	0.90
NRF2	regulates	gene	0.90
JAK	activates	gene	0.90
glioblastoma	affects	disease	0.90
complement cascade	active_in	pathway	0.90
Rett syndrome	affects	disease	0.90
axon	found_in	organelle	0.90
epigenetic regulation	active_in	pathway	0.90
TNF	activates	gene	0.90
AKT	activates	gene	0.90
BDNF	activates	gene	0.90
depression	affects	disease	0.90
HDAC3	activates	gene	0.90
epilepsy	affects	disease	0.90
GFAP	activates	gene	0.90
YAP	regulates	gene	0.90
YAP	activates	gene	0.90
HDAC3	regulates	gene	0.90
frontotemporal dementia	affects	disease	0.90
SQSTM1	activates	gene	0.90
LC3	activates	gene	0.90
ALS	affects	disease	0.90
LC3B	activates	gene	0.90
DNA	regulates	gene	0.90
ROS	activates	gene	0.90
DNA	activates	gene	0.90
ALS	activates	gene	0.90
Parkinson's disease	affects	disease	0.90
PIK3C3	activates	gene	0.90
ATP	activates	gene	0.90
NLRP3	activates	gene	0.90
MAP1LC3B	activates	gene	0.90
neuroinflammation	affects	disease	0.90
RNA	inhibits	gene	0.90
BECN1	activates	gene	0.90
PINK1	activates	gene	0.90
RNA	regulates	gene	0.90
ACTB	activates	gene	0.90
PTEN	activates	gene	0.90
OPTN	activates	gene	0.90
necroptosis	active_in	pathway	0.90
RNA	treats	gene	0.90
ATG	activates	gene	0.90
EGFR	activates	gene	0.90
CTSD	activates	gene	0.90
autophagy pathway	active_in	pathway	0.90
MTORC1	activates	gene	0.90
neurodegeneration	affects	disease	0.90
MTOR	activates	gene	0.90

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning NEURAL STEM CELLS in their description or question text

No additional research found