GRIA1

Understanding Entity Pages

This page aggregates everything SciDEX knows about GRIA1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

GRIA1 is a gene implicated in neurodegeneration research. Key relationships include: interacts with, activates, therapeutic target. Associated with Als, Alzheimer, Huntington. Connected to 38 entities in the SciDEX knowledge graph.

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graph TD
    GRIA1["GRIA1"]
    Ms{"Ms"}
    GRIA1 -->|"activates"| Ms
    Als{"Als"}
    GRIA1 -->|"activates"| Als
    Parkinson{"Parkinson"}
    GRIA1 -->|"therapeutic target"| Parkinson
    Alzheimer{"Alzheimer"}
    GRIA1 -->|"therapeutic target"| Alzheimer
    Huntington{"Huntington"}
    GRIA1 -->|"therapeutic target"| Huntington
    GRIA1 -->|"therapeutic target"| Ms
    ADRA1A["ADRA1A"]
    GRIA1 -->|"activates"| ADRA1A
    HRH1["HRH1"]
    GRIA1 -->|"activates"| HRH1
    GRIN1["GRIN1"]
    GRIA1 -->|"activates"| GRIN1
    HCRTR1["HCRTR1"]
    GRIA1 -->|"activates"| HCRTR1
    Epigenetic(["Epigenetic"])
    GRIA1 -->|"activates"| Epigenetic
    Dna_Methylation(["Dna Methylation"])
    GRIA1 -->|"activates"| Dna_Methylation
    DRD2["DRD2"]
    DRD2 -->|"activates"| GRIA1
    HRH3["HRH3"]
    HRH3 -->|"activates"| GRIA1
    HCRTR2["HCRTR2"]
    HCRTR2 -->|"activates"| GRIA1
    ADRA1B["ADRA1B"]
    ADRA1B -->|"activates"| GRIA1
    DRD1["DRD1"]
    DRD1 -->|"activates"| GRIA1
    CCT2["CCT2"]
    CCT2 -->|"interacts with"| GRIA1
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"therapeutic target"| GRIA1
    GFAP["GFAP"]
    GFAP -->|"interacts with"| GRIA1
    style GRIA1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0