gene

CACNA1B

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CACNA1B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

155Connections
0Hypotheses
0Analyses
50Outgoing
46Incoming
0Experiments
0Debates

Summary

CACNA1B is a gene implicated in neurodegeneration research. Key relationships include: associated with, causes, expressed in. Associated with Cancer. Connected to 59 entities in the SciDEX knowledge graph.

View on Wiki →

No AI portrait yet

🧬 Gene Info
Gene SymbolCACNA1B
Full NameCalcium Voltage-Gated Channel Subunit Alpha1 B
Chromosome9q34.3
Functionof approximately 2339 amino acids
Primary ExpressionBrain (neurons), Spinal cord, Peripheral nervous system
Molecular Weight250 kDa
Amino Acids2339 aa
Exons47
UniProt IDQ00962
NCBI Gene ID785
Ensembl IDENSG00000148438
OMIM601314
GeneCardsCACNA1B
Human Protein AtlasCACNA1B
Associated DiseasesAlzheimer, Autism, Bipolar, Cancer, Inflammation, Parkinson
InteractionsCACNA1H, DRD1, DRD2, GABRA1, GABRB2, GRIA1
KG Connections155 knowledge graph edges
DatabasesGeneCardsHPASTRING
🔮 Predicted Structure: CACNA1B — AlphaFold Q00962 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

CACNA1B Gene

gene · 2064 words

CACNA1B Protein

protein · 636 words

Pathway Diagram

graph TD
    CACNA1B["CACNA1B"]
    Cancer{"Cancer"}
    CACNA1B -->|"associated with"| Cancer
    SCNN1A["SCNN1A"]
    CACNA1B -->|"associated with"| SCNN1A
    CFTR["CFTR"]
    CACNA1B -->|"associated with"| CFTR
    PIEZO2["PIEZO2"]
    CACNA1B -->|"associated with"| PIEZO2
    TRPA1["TRPA1"]
    CACNA1B -->|"associated with"| TRPA1
    KCNMA1["KCNMA1"]
    CACNA1B -->|"associated with"| KCNMA1
    TRPV1["TRPV1"]
    CACNA1B -->|"associated with"| TRPV1
    KCNN4["KCNN4"]
    CACNA1B -->|"associated with"| KCNN4
    KCNQ1["KCNQ1"]
    CACNA1B -->|"associated with"| KCNQ1
    CACNA1C["CACNA1C"]
    CACNA1B -->|"associated with"| CACNA1C
    Oxidative_Phosphorylation(["Oxidative Phosphorylation"])
    CACNA1B -->|"associated with"| Oxidative_Phosphorylation
    Wnt(["Wnt"])
    CACNA1B -->|"associated with"| Wnt
    PIEZO1["PIEZO1"]
    PIEZO1 -->|"associated with"| CACNA1B
    KCNK2["KCNK2"]
    KCNK2 -->|"associated with"| CACNA1B
    SCN5A["SCN5A"]
    SCN5A -->|"associated with"| CACNA1B
    TRPM7["TRPM7"]
    TRPM7 -->|"associated with"| CACNA1B
    SCN1A["SCN1A"]
    SCN1A -->|"associated with"| CACNA1B
    TRPV4["TRPV4"]
    TRPV4 -->|"associated with"| CACNA1B
    KCNMA1 -->|"causes"| CACNA1B
    KCNQ1 -->|"causes"| CACNA1B
    PIEZO1 -->|"causes"| CACNA1B
    CANCER["CANCER"]
    CANCER -->|"associated with"| CACNA1B
    HIPPO["HIPPO"]
    HIPPO -->|"associated with"| CACNA1B
    CFTR -->|"causes"| CACNA1B
    style CACNA1B fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (109)

TargetRelationTypeStr
Autismassociated_withdisease0.65
Parkinsonassociated_withdisease0.65
Alzheimerassociated_withdisease0.65
Schizophreniaassociated_withdisease0.65
Bipolarassociated_withdisease0.65

Incoming (46)

SourceRelationTypeStr
KCNMA1causesgene0.60
KCNQ1causesgene0.60
PIEZO1causesgene0.60
CFTRcausesgene0.60
SCN1Acausesgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CACNA1B in their description or question text

No additional research found