| Gene Symbol | GRIA1 |
| Full Name | Glutamate Ionotropic Receptor AMPA Type Subunit 1 |
| Chromosome | 5q31.1 |
| Function | The GRIA1 gene encodes the GluA1 protein subunit, one of four subunits (GluA1-4) that assemble to form AMPA-type ionotropic glutamate receptors. |
| Pathways | Epigenetic, Synaptic Plasticity |
| UniProt ID | P42262 |
| NCBI Gene ID | 2891 |
| Ensembl ID | ENSG00000155545 |
| OMIM | 138248 |
| GeneCards | GRIA1 |
| Human Protein Atlas | GRIA1 |
| Fast synaptic transmission | Mediates rapid excitatory signaling |
| Synaptic plasticity | Critical for long-term potentiation |
| Learning and memory | Required for hippocampal synaptic plasticity |
| Disease associations | Epilepsy, autism, intellectual disability, Alzheimer's disease |
| Associated Diseases | aging, Als, Alzheimer, Autism, Bipolar |
| Interactions | ACTB, ACTG1, AD, ADRA1A, ADRA1B, AKT |
| KG Connections | 212 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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