Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CNP: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | CNP |
| Key Genes/Proteins | AMBRA1, ATG5, ATG7, ATP, BAK1, BAX |
| Related Pathways | APOPTOSIS, apoptosis pathway, AUTOPHAGY, autophagy pathway |
graph TD
CNP[CNP]
CNP -->|provides_data_for| ds_f2c28aed24a7[ds-f2c28aed24a7]
CNP -->|activates| DNM1L[DNM1L]
CNP -->|activates| DRP1[DRP1]
CNP -->|activates| FUNDC1[FUNDC1]
CNP -->|activates| GSK3B[GSK3B]
CNP -->|activates| GSR[GSR]
CNP -->|activates| HIF1A[HIF1A]
CNP -->|activates| HUWE1[HUWE1]
CNP -->|activates| IL1B[IL1B]
CNP -->|activates| LC3[LC3]
ds_f2c28aed24a7 -->|data_in| CNP
CASP1[CASP1] -->|activates| CNP
AMBRA1[AMBRA1] -->|activates| CNP
BAK1[BAK1] -->|activates| CNP
BAX[BAX] -->|activates| CNP
BCL2[BCL2] -->|activates| CNP
BECN1[BECN1] -->|activates| CNP
BNIP3[BNIP3] -->|activates| CNP
BNIP3L[BNIP3L] -->|activates| CNP
CAT[CAT] -->|activates| CNP| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:CNP | data_in | dataset_row | 0.00 |
| ds-f2c28aed24a7 | provides_data_for | dataset | 1.00 |
| GFAP | activates | gene | 0.70 |
| LAMP1 | activates | gene | 0.70 |
| MBP | activates | gene | 0.70 |
| OLIGODENDROCYTE | regulates | cell_type | 0.70 |
| OLIGODENDROCYTES | regulates | cell_type | 0.70 |
| SOD2 | activates | gene | 0.70 |
| GSK3B | transports | gene | 0.70 |
| MITOPHAGY | activates | pathway | 0.60 |
| NEURON | co_discussed | cell_type | 0.60 |
| NEURONS | co_discussed | cell_type | 0.60 |
| OLIGODENDROCYTE | enhances | cell_type | 0.60 |
| OLIGODENDROCYTES | enhances | cell_type | 0.60 |
| MAG | associated_with | gene | 0.60 |
| MOG | associated_with | gene | 0.60 |
| RELN | associated_with | gene | 0.60 |
| GSK3B | co_discussed | gene | 0.60 |
| NFKB | co_discussed | gene | 0.60 |
| VEGF | associated_with | gene | 0.60 |
| NEFL | associated_with | gene | 0.60 |
| NPTX1 | associated_with | gene | 0.60 |
| RBFOX3 | associated_with | gene | 0.60 |
| MMP1 | associated_with | gene | 0.60 |
| VEGF | causes | gene | 0.60 |
| G6PD | activates | gene | 0.60 |
| GSH | activates | gene | 0.60 |
| NADPH | activates | gene | 0.60 |
| NIX | activates | gene | 0.60 |
| NLR | activates | gene | 0.60 |
| NOX | activates | gene | 0.60 |
| Wnt signaling | participates_in | pathway | 0.60 |
| autophagy pathway | participates_in | pathway | 0.60 |
| apoptosis pathway | participates_in | pathway | 0.60 |
| oxidative stress response | participates_in | pathway | 0.60 |
| ubiquitin-proteasome | participates_in | pathway | 0.60 |
| ROS | activates | gene | 0.60 |
| FTLD | associated_with | gene | 0.60 |
| DNM1L | activates | gene | 0.60 |
| DRP1 | activates | gene | 0.60 |
| FUNDC1 | activates | gene | 0.60 |
| GSK3B | activates | gene | 0.60 |
| GSR | activates | gene | 0.60 |
| HIF1A | activates | gene | 0.60 |
| HUWE1 | activates | gene | 0.60 |
| IL1B | activates | gene | 0.60 |
| LC3 | activates | gene | 0.60 |
| MUL1 | activates | gene | 0.60 |
| NLRP3 | activates | gene | 0.60 |
| OPA1 | activates | gene | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:CNP | data_in | dataset_row | 0.00 |
| ds-f2c28aed24a7 | data_in | dataset | 1.00 |
| ATG5 | regulates | gene | 0.70 |
| ATG7 | regulates | gene | 0.70 |
| BECN1 | regulates | gene | 0.70 |
| CASP1 | activates | gene | 0.70 |
| CCL25 | associated_with | gene | 0.60 |
| AUTOPHAGY | regulates | pathway | 0.60 |
| BCL2 | regulates | gene | 0.60 |
| BAK1 | activates | gene | 0.60 |
| BAX | activates | gene | 0.60 |
| BCL2 | activates | gene | 0.60 |
| BECN1 | activates | gene | 0.60 |
| BNIP3 | activates | gene | 0.60 |
| BNIP3L | activates | gene | 0.60 |
| CAT | activates | gene | 0.60 |
| AMBRA1 | activates | gene | 0.60 |
| ATP | activates | gene | 0.60 |
| APOPTOSIS | activates | pathway | 0.60 |
| AUTOPHAGY | activates | pathway | 0.60 |
| BIN1 | associated_with | gene | 0.60 |
| BIN1 | co_discussed | gene | 0.60 |
| ISCHEMIA | associated_with | disease | 0.50 |
| CCL2 | co_discussed | gene | 0.40 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning CNP in their description or question text
No additional research found