concept

BAMBI

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about BAMBI: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

127Connections

0Hypotheses

0Analyses

50Outgoing

49Incoming

0Experiments

0Debates

Summary

BAMBI is a concept in neurodegeneration research. Key relationships include: therapeutic target, regulates, inhibits. Associated with Als, Cancer, Carcinoma. Connected to 98 entities in the SciDEX knowledge graph.

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💡 Concept Info

Name	BAMBI
Key Genes/Proteins	ABCB1, ACSL5, ALDH1A1, AND, APC, ATF3
Related Diseases	Als, Cancer, Carcinoma, CARCINOMA

Pathway Diagram

graph TD
    BAMBI["BAMBI"]
    BAMBI -->|"regulates"| ACSL5["ACSL5"]
    BAMBI -->|"activates"| Carcinoma["Carcinoma"]
    BAMBI -->|"inhibits"| Ms["Ms"]
    BAMBI -->|"target for"| Fibrosis["Fibrosis"]
    BAMBI -->|"target for"| Hepatitis["Hepatitis"]
    BAMBI -->|"target for"| Cancer["Cancer"]
    BAMBI -->|"target for"| Als["Als"]
    BAMBI -->|"target for"| Inflammation["Inflammation"]
    PPARGC1A["PPARGC1A"] -->|"inhibits"| BAMBI
    WTAP["WTAP"] -->|"inhibits"| BAMBI
    ACSL5 -->|"regulates"| BAMBI
    FGF20["FGF20"] -->|"target for"| BAMBI
    BRG1["BRG1"] -->|"target for"| BAMBI
    NRCAM["NRCAM"] -->|"target for"| BAMBI
    NOTCH2["NOTCH2"] -->|"target for"| BAMBI
    EP300["EP300"] -->|"target for"| BAMBI
    CTNNB1["CTNNB1"] -->|"target for"| BAMBI
    NEUROD1["NEUROD1"] -->|"target for"| BAMBI

Outgoing (78)

Target	Relation	Type	Str
TGF-β/SMAD Signaling	involved_in	pathway	0.80
ACSL5	regulates	gene	0.72
Lung Cancer	therapeutic_target	disease	0.65
Ms	inhibits	disease	0.65
Pancreatic Cancer	therapeutic_target	disease	0.65
Gastric Cancer	therapeutic_target	disease	0.65
Carcinoma	activates	disease	0.65
Prostate Cancer	therapeutic_target	disease	0.65
Infection	therapeutic_target	disease	0.65
Hepatocellular Carcinoma	therapeutic_target	disease	0.65
Colorectal Cancer	therapeutic_target	disease	0.65
Liver Cancer	therapeutic_target	disease	0.65
Pulmonary Fibrosis	therapeutic_target	disease	0.65
Cancer	therapeutic_target	disease	0.65
Als	therapeutic_target	disease	0.65
Inflammation	therapeutic_target	disease	0.65
Ms	therapeutic_target	disease	0.65
Fibrosis	therapeutic_target	disease	0.65
Hepatitis	therapeutic_target	disease	0.65
Carcinoma	therapeutic_target	disease	0.65
TGFB_SIGNALING	participates_in	pathway	0.64
CD44	targets	gene	0.60
FGF18	targets	gene	0.60
MYC	targets	gene	0.60
NRCAM	targets	gene	0.60
TERT	targets	gene	0.60
NOTCH2	targets	gene	0.60
NEUROD1	targets	gene	0.60
FGF20	targets	gene	0.60
VEGFA	targets	gene	0.60
FZD7	targets	gene	0.60
JAG1	targets	gene	0.60
MITF	targets	gene	0.60
PPARGC1A	regulates	gene	0.60
METTL3	inhibits	gene	0.60
Wnt	inhibits	pathway	0.60
Ferroptosis	regulates	pathway	0.60
METTL3	activates	gene	0.60
WTAP	activates	gene	0.60
BRG1	therapeutic_target	gene	0.60
SMARCA4	therapeutic_target	gene	0.60
AXIN2	therapeutic_target	gene	0.60
FOXM1	therapeutic_target	gene	0.60
FERROPTOSIS	regulates	gene	0.60
WTAP	inhibits	gene	0.60
ALDH1A1	therapeutic_target	gene	0.60
CANCER	therapeutic_target	gene	0.60
Tgf-Β	regulates	pathway	0.60
ROS	regulates	gene	0.60
AND	regulates	gene	0.60

Incoming (49)

Source	Relation	Type	Str
PPARGC1A	associated_with	gene	0.80
PPARGC1A	inhibits	gene	0.72
AXIN2	targets	gene	0.60
ALDH1A1	targets	gene	0.60
WTAP	inhibits	gene	0.60
ACSL5	regulates	gene	0.60
DKK1	therapeutic_target	gene	0.60
ABCB1	targets	gene	0.60
FERROPTOSIS	regulates	gene	0.60
ROS	regulates	gene	0.60
METTL3	inhibits	gene	0.60
APC	therapeutic_target	gene	0.60
ATF3	targets	gene	0.60
FGF20	therapeutic_target	gene	0.60
BRG1	therapeutic_target	gene	0.60
NRCAM	therapeutic_target	gene	0.60
NOTCH2	therapeutic_target	gene	0.60
EP300	therapeutic_target	gene	0.60
CTNNB1	therapeutic_target	gene	0.60
NEUROD1	therapeutic_target	gene	0.60
MYC	therapeutic_target	gene	0.60
VEGFA	therapeutic_target	gene	0.60
FOXM1	therapeutic_target	gene	0.60
LEF1	therapeutic_target	gene	0.60
SMARCA4	therapeutic_target	gene	0.60
TERT	therapeutic_target	gene	0.60
CDH1	therapeutic_target	gene	0.60
GENES	therapeutic_target	gene	0.60
FZD7	therapeutic_target	gene	0.60
JAG1	therapeutic_target	gene	0.60
MITF	therapeutic_target	gene	0.60
GAIN	therapeutic_target	gene	0.60
CD44	therapeutic_target	gene	0.60
FGF18	therapeutic_target	gene	0.60
CANCER	therapeutic_target	gene	0.60
CLDN1	therapeutic_target	gene	0.60
AXIN1	therapeutic_target	gene	0.60
INFLAMMATION	therapeutic_target	gene	0.60
PPARGC1A	regulates	gene	0.60
IL10	therapeutic_target	gene	0.60
PPARD	therapeutic_target	gene	0.60
CREBBP	therapeutic_target	gene	0.60
WNT	inhibits	gene	0.60
ACSL5	associated_with	gene	0.60
PPARGC1A	activates	gene	0.50
CARCINOMA	activates	disease	0.50
SMAD	regulates	protein	0.50
Tgf-Β	regulates	pathway	0.50
ferroptosis	regulates	phenotype	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning BAMBI in their description or question text

No additional research found