disease

Liver Cancer

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about Liver Cancer: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

360Connections

0Hypotheses

0Analyses

50Outgoing

50Incoming

0Experiments

0Debates

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Disease Info

Associated Genes	AKT, APOPTOSIS, ATP, AUTOPHAGY, CANCER, GAIN, GENES, INFLAMMATION
KG Connections	343 knowledge graph edges
Databases	OMIM Orphanet ClinicalTrials PubMed

Wiki Pages (1)

Knowledge base pages for this entity

DLC1 Gene - Deleted in Liver Cancer 1

gene · 649 words

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Pathway Diagram

graph TD
    Liver_Cancer["Liver Cancer"]
    Als{"Als"}
    Liver_Cancer -->|"therapeutic_target"| Als
    Carcinoma{"Carcinoma"}
    Liver_Cancer -->|"associated_with"| Carcinoma
    Hepatitis{"Hepatitis"}
    Liver_Cancer -->|"associated_with"| Hepatitis
    Autophagy["Autophagy"]
    Liver_Cancer -->|"therapeutic_target"| Autophagy
    Mtor["Mtor"]
    Liver_Cancer -.->|"inhibits"| Mtor
    CANCER(["CANCER"])
    CANCER -->|"associated_with"| Liver_Cancer
    Cancer{"Cancer"}
    Cancer -->|"associated_with"| Liver_Cancer
    style Liver_Cancer fill:#1a3a4a,stroke:#ef5350,stroke-width:3px,color:#e0e0e0

Outgoing (114)

Target	Relation	Type	Str
Als	therapeutic_target	disease	1.00
Carcinoma	associated_with	disease	1.00
Carcinoma	therapeutic_target	disease	1.00
Hepatitis	associated_with	disease	0.85
Infectious Agent Exposure	risk_factor_for	process	0.85
Autophagy	therapeutic_target	pathway	0.80
Mtor	inhibits	pathway	0.80
Ferroptosis	activates	pathway	0.80
Carcinoma	activates	disease	0.75
Inflammation	therapeutic_target	disease	0.75
Hepatitis	therapeutic_target	disease	0.75
Nf-Κb	implicated_in	pathway	0.70
Wnt	therapeutic_target	pathway	0.70
Metastasis	activates	pathway	0.70
Mtor	therapeutic_target	pathway	0.70
Glycolysis	inhibits	pathway	0.70
Mtor	treats	pathway	0.70
Als	treats	disease	0.65
Carcinoma	inhibits	disease	0.65
Als	expressed_in	disease	0.65
Inflammation	regulates	disease	0.65
Als	associated_with	disease	0.65
Nafld	associated_with	disease	0.65
Lipid Metabolism	treats	pathway	0.60
Unfolded Protein Response	therapeutic_target	pathway	0.60
Glycolysis	therapeutic_target	pathway	0.60
Chaperone	therapeutic_target	pathway	0.60
Er Stress	associated_with	pathway	0.60
Epigenetic	treats	pathway	0.60
Angiogenesis	regulates	pathway	0.60
Epigenetic	therapeutic_target	pathway	0.60
Apoptosis	regulates	pathway	0.60
Immune Response	regulates	pathway	0.60
Cell Cycle	activates	pathway	0.60
Senescence	activates	pathway	0.60
Nf-Κb	activates	pathway	0.60
Notch	therapeutic_target	pathway	0.60
Notch	expressed_in	pathway	0.60
Microrna	therapeutic_target	pathway	0.60
Pi3K/Akt	therapeutic_target	pathway	0.60
Lipid Metabolism	therapeutic_target	pathway	0.60
Apoptosis	inhibits	pathway	0.60
Invasion	expressed_in	pathway	0.60
Stem Cell	implicated_in	pathway	0.60
Epithelial-Mesenchymal Transition	expressed_in	pathway	0.60
Pi3K/Akt	expressed_in	pathway	0.60
Metastasis	therapeutic_target	pathway	0.60
Tgf-Β	therapeutic_target	pathway	0.60
Differentiation	expressed_in	pathway	0.60
Pi3K/Akt	inhibits	pathway	0.60

Incoming (246)

Source	Relation	Type	Str
Tumor	therapeutic_target	disease	1.00
Cancer	associated_with	disease	1.00
CANCER	associated_with	gene	1.00
Cancer	therapeutic_target	disease	1.00
CANCER	therapeutic_target	gene	1.00
CANCER	activates	gene	1.00
Cancer	activates	disease	0.95
CANCER	expressed_in	gene	0.95
Hepatocellular Carcinoma	therapeutic_target	disease	0.95
Hepatocellular Carcinoma	associated_with	disease	0.95
CTNNB1	risk_factor_for	gene	0.94
SLC13A3	therapeutic_target	gene	0.93
GENES	inhibits	gene	0.85
GENES	therapeutic_target	gene	0.85
AUTOPHAGY	therapeutic_target	gene	0.85
FERROPTOSIS	activates	gene	0.85
Cancer	expressed_in	disease	0.85
INFLAMMATION	therapeutic_target	gene	0.85
kaempferitrin	treats	drug	0.80
Mitochondrial Cholesterol Accumulation	contributes_to	process	0.80
MTOR	inhibits	gene	0.75
GPX4	activates	gene	0.75
AKT	treats	gene	0.75
STAT3	implicated_in	gene	0.75
NF-ΚB	implicated_in	gene	0.75
INFLAMMATION	regulates	gene	0.75
MTOR	treats	gene	0.75
MTOR	therapeutic_target	gene	0.75
Tumor	associated_with	disease	0.75
AKT	expressed_in	gene	0.75
GAIN	expressed_in	gene	0.75
Tumor	expressed_in	disease	0.75
ERK	inhibits	gene	0.75
Tumor	activates	disease	0.75
Infection	associated_with	disease	0.75
CANCER	causes	gene	0.75
PI3K	activates	gene	0.75
DNA	inhibits	gene	0.75
AKT	activates	gene	0.75
autophagy	associated_with	process	0.70
FGF20	therapeutic_target	gene	0.65
ABCB1	therapeutic_target	gene	0.65
APC	therapeutic_target	gene	0.65
DKK1	therapeutic_target	gene	0.65
BAMBI	therapeutic_target	gene	0.65
JAG1	therapeutic_target	gene	0.65
ATF3	therapeutic_target	gene	0.65
CD44	therapeutic_target	gene	0.65
AXIN1	therapeutic_target	gene	0.65
ALDH1A1	therapeutic_target	gene	0.65

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning Liver Cancer in their description or question text

No additional research found