concept

CBP

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CBP: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

106Connections

0Hypotheses

0Analyses

50Outgoing

19Incoming

0Experiments

0Debates

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💡 Concept Info

Name	CBP
Key Genes/Proteins	ACAT1, ACLY, AMPK, APC, ATG, AXIN1
Related Pathways	apoptosis pathway, autophagy pathway

Wiki Pages (3)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    CBP[CBP]
    CBP -->|activates| BDNF[BDNF]
    CBP -->|inhibits| SIRT1[SIRT1]
    CBP -->|participates in| epigenetic_regulation[epigenetic regulation]
    CBP -->|regulates| CREB[CREB]
    CBP -->|activates| NEURODEGENERATION[NEURODEGENERATION]
    CBP -->|regulates| NEURONS[NEURONS]
    CBP -->|activates| CREBBP[CREBBP]
    CBP -->|activates| EP300[EP300]
    ASTROCYTES[ASTROCYTES] -->|activates| CBP
    BECN1[BECN1] -->|activates| CBP
    CALCOCO2[CALCOCO2] -->|activates| CBP
    BDNF -->|regulates| CBP
    APC[APC] -->|regulates| CBP
    AXIN1[AXIN1] -->|regulates| CBP
    AXIN2[AXIN2] -->|regulates| CBP
    BRG1[BRG1] -->|regulates| CBP
    ACAT1[ACAT1] -->|activates| CBP
    AMPK[AMPK] -->|activates| CBP

Outgoing (87)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:CBP	data_in	dataset_row	0.00
BDNF	activates	gene	0.90
SIRT1	inhibits	gene	0.70
epigenetic regulation	participates_in	pathway	0.70
NEURODEGENERATION	activates	phenotype	0.70
CREB	regulates	gene	0.70
CREB	inhibits	gene	0.65
NEURONS	regulates	cell_type	0.65
BDNF	regulates	protein	0.64
RUBCNL	activates	gene	0.60
Parkinson's disease	activates	disease	0.60
autophagy pathway	participates_in	pathway	0.60
apoptosis pathway	participates_in	pathway	0.60
Wnt signaling	participates_in	pathway	0.60
ubiquitin-proteasome	participates_in	pathway	0.60
neurons	expressed_in	cell_type	0.60
CDH1	regulates	gene	0.60
CREB	interacts_with	gene	0.60
neurodegeneration	activates	disease	0.60
CREB	activates	gene	0.60
pericytes	expressed_in	cell_type	0.60
GSK3	activates	gene	0.60
MAP1LC3	activates	gene	0.60
PKM2	activates	gene	0.60
VPS34	activates	gene	0.60
CREBBP	regulates	gene	0.60
CTNNB1	regulates	gene	0.60
EP300	regulates	gene	0.60
FOXM1	regulates	gene	0.60
MUC1	regulates	gene	0.60
MUC16	regulates	gene	0.60
SMARCA4	regulates	gene	0.60
EP300	interacts_with	gene	0.60
P300	interacts_with	gene	0.60
SIRT1	interacts_with	gene	0.60
HSC70	activates	gene	0.60
SNARE	activates	gene	0.60
CDH5	regulates	gene	0.60
oxidative stress response	participates_in	pathway	0.60
traumatic brain injury	activates	disease	0.60
traumatic brain injury	inhibits	disease	0.60
CSF1R	activates	gene	0.60
GAPDH	activates	gene	0.60
HDAC6	activates	gene	0.60
HSPA8	activates	gene	0.60
KAT2A	activates	gene	0.60
KAT2B	activates	gene	0.60
KAT5	activates	gene	0.60
KAT8	activates	gene	0.60
LAMP2A	activates	gene	0.60

Incoming (19)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:CBP	data_in	dataset_row	0.00
ASTROCYTES	activates	cell_type	0.70
BRG1	regulates	gene	0.60
AXIN2	regulates	gene	0.60
ACAT1	activates	gene	0.60
AMPK	activates	gene	0.60
ATG	activates	gene	0.60
rapamycin	targets	drug	0.60
AXIN1	regulates	gene	0.60
APC	regulates	gene	0.60
AMPK	regulates	gene	0.60
BECN1	activates	gene	0.60
CALCOCO2	activates	gene	0.60
BDNF	regulates	gene	0.60
BDNF	activates	gene	0.55
ACLY	activates	gene	0.55
RAPAMYCIN	associated_with	drug	0.45
HIPPOCAMPUS	associated_with	brain_region	0.45
PARKINSON	associated_with	disease	0.45

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CBP in their description or question text

No additional research found

CBP