concept

MUC16

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MUC16: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

22Connections

0Hypotheses

0Analyses

7Outgoing

15Incoming

0Experiments

0Debates

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💡 Concept Info

Name	MUC16
Key Genes/Proteins	APC, AXIN1, AXIN2, BRG1, CBP, CDH1
Related Pathways	epigenetic regulation

Pathway Diagram

graph TD
    MUC16[MUC16]
    MUC16 -->|regulates| SMARCA4[SMARCA4]
    MUC16 -->|participates in| epigenetic_regulation[epigenetic regulation]
    MUC16 -->|data_in| benchmark_ot_ad_answer_key_MUC[benchmark_ot_ad_answer_key:MUC16]
    APC[APC] -->|regulates| MUC16
    AXIN1[AXIN1] -->|regulates| MUC16
    AXIN2[AXIN2] -->|regulates| MUC16
    BRG1[BRG1] -->|regulates| MUC16
    CBP[CBP] -->|regulates| MUC16
    CDH5[CDH5] -->|regulates| MUC16
    CREBBP[CREBBP] -->|regulates| MUC16
    CTNNB1[CTNNB1] -->|regulates| MUC16
    EP300[EP300] -->|regulates| MUC16
    FOXM1[FOXM1] -->|regulates| MUC16

Outgoing (7)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:MUC16	data_in	dataset_row	0.00
Lung Cancer Brain Metastasis	associated_with	disease	0.85
SMARCA4	regulates	gene	0.60
RYR2	associated_with	gene	0.60
TTN	associated_with	gene	0.60
epigenetic regulation	participates_in	pathway	0.60
TP53	associated_with	gene	0.60

Incoming (15)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:MUC16	data_in	dataset_row	0.00
EGFR	associated_with	gene	0.60
LRP1B	associated_with	gene	0.60
CDH1	regulates	gene	0.60
APC	regulates	gene	0.60
AXIN1	regulates	gene	0.60
AXIN2	regulates	gene	0.60
BRG1	regulates	gene	0.60
CBP	regulates	gene	0.60
CDH5	regulates	gene	0.60
CREBBP	regulates	gene	0.60
CTNNB1	regulates	gene	0.60
EP300	regulates	gene	0.60
FOXM1	regulates	gene	0.60
MUC1	regulates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning MUC16 in their description or question text

No additional research found