IL-1

Understanding Entity Pages

This page aggregates everything SciDEX knows about IL-1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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graph TD
    IL_1["IL-1"]
    style IL_1 fill:#1a237e,stroke:#4fc3f7,stroke-width:3px
    IL_1 -->|"contributes to"| Atherosclerosis["Atherosclerosis"]
    IL_1 -->|"mediates"| Inflammatory_Senescence_Associ(Inflammatory Senescence-Associated Secretory Phenotype)
    IL_1 -->|"activates"| Ms["Ms"]
    IL_1 -->|"activates"| Tumor["Tumor"]
    IL_1 -->|"activates"| Inflammation["Inflammation"]
    IL_1 -->|"activates"| Alzheimer["Alzheimer"]
    IL_1 -->|"activates"| Aging["Aging"]
    IL_1 -->|"activates"| Phagocytosis["Phagocytosis"]
    IL_1 -->|"activates"| OCLN([OCLN])
    IL_1 -->|"activates"| MLCK([MLCK])
    NLRP3([NLRP3]) -->|"activates"| IL_1
    IL_17([IL-17]) -->|"co_expressed_with"| IL_1
    DISEASE_ASSOCIATED_MICROGLIA([DISEASE-ASSOCIATED MICROGLIA]) -->|"activates"| IL_1
    TNFR1([TNFR1]) -->|"activates"| IL_1
    AND([AND]) -->|"activates"| IL_1
    MICROGLIA([MICROGLIA]) -->|"activates"| IL_1
    MYELIN([MYELIN]) -->|"activates"| IL_1
    CYTOKINES([CYTOKINES]) -->|"activates"| IL_1
    NEURODEGENERATIVE_DISEASES([NEURODEGENERATIVE DISEASES]) -->|"activates"| IL_1
    PHAGOCYTOSIS([PHAGOCYTOSIS]) -->|"activates"| IL_1