| Gene Symbol | IL |
| Full Name | 10 Protein — Interleukin-10 |
| Function | Interleukin-1 beta (IL-1β) is a potent pro-inflammatory cytokine that plays a central role in the innate immune response and neuroinflammation. |
| Subcellular Localization | </strong></td><td>Secreted (extracellular)</td></tr> |
| GeneCards | IL |
| Human Protein Atlas | IL |
| IL-10R1 (CDW210a) | The ligand-binding chain, expressed on most hematopoietic cells and, importantly, on microglia, astrocytes, and some neurons. It belongs to the Class II cytokine receptor family |
| IL-10R2 (CRFB4) | The signal-transducing accessory chain, broadly expressed on nearly all cell types. It does not bind IL-10 directly but is required for signal propagation |
| PI3K-AKT pathway | Promotes cell survival and anti-apoptotic gene expression |
| MAPK/ERK pathway | Involved in some of the immunomodulatory effects |
| NF-κB inhibition | STAT3 can directly or indirectly suppress NF-κB transcriptional activity, creating powerful anti-inflammatory effects |
| Associated Diseases | CRC |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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