concept

INTERLEUKIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about INTERLEUKIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

663Connections

0Hypotheses

0Analyses

50Outgoing

50Incoming

0Experiments

0Debates

No summary available yet.

View on Wiki →

No AI portrait yet

💡 Concept Info

Name	INTERLEUKIN

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Interleukin-6 (IL-6)

entity · 957 words

→

Pathway Diagram

graph TD
    INTERLEUKIN["INTERLEUKIN"]
    style INTERLEUKIN fill:#1a237e,stroke:#4fc3f7,stroke-width:3px
    INTERLEUKIN -->|"regulates"| Fibrosis["Fibrosis"]
    INTERLEUKIN -->|"target for"| Als["Als"]
    INTERLEUKIN -->|"interacts"| Cancer["Cancer"]
    INTERLEUKIN -->|"target for"| Multiple_Sclerosis["Multiple Sclerosis"]
    INTERLEUKIN -->|"target for"| Neuroinflammation["Neuroinflammation"]
    REL([REL]) -->|"regulates"| INTERLEUKIN
    IL_10([IL-10]) -->|"activates"| INTERLEUKIN
    CERS2([CERS2]) -->|"regulates"| INTERLEUKIN
    IGF1R([IGF1R]) -->|"regulates"| INTERLEUKIN
    DAG1([DAG1]) -->|"regulates"| INTERLEUKIN
    RNA([RNA]) -->|"regulates"| INTERLEUKIN
    ROS([ROS]) -->|"regulates"| INTERLEUKIN
    HSPG2([HSPG2]) -->|"regulates"| INTERLEUKIN
    RIPK1([RIPK1]) -->|"interacts"| INTERLEUKIN
    PPARG([PPARG]) -->|"interacts"| INTERLEUKIN

Outgoing (189)

Target	Relation	Type	Str
Aging	inhibits	disease	0.60
Neuroinflammation	expressed_in	disease	0.60
Atherosclerosis	associated_with	disease	0.60
Stroke	activates	disease	0.60
Als	inhibits	disease	0.60
Parkinson	expressed_in	disease	0.60
Neurodegeneration	expressed_in	disease	0.60
Encephalitis	associated_with	disease	0.60
Neuroinflammation	therapeutic_target	disease	0.60
Als	regulates	disease	0.60
Neurodegeneration	inhibits	disease	0.60
Parkinson	regulates	disease	0.60
Traumatic Brain Injury	inhibits	disease	0.60
Aging	associated_with	disease	0.60
Aging	expressed_in	disease	0.60
Encephalitis	activates	disease	0.60
Spinal Cord Injury	activates	disease	0.60
Diabetes	activates	disease	0.60
Hypertension	associated_with	disease	0.60
Multiple Sclerosis	therapeutic_target	disease	0.60
Cancer	expressed_in	disease	0.60
Dementia	activates	disease	0.60
Amyotrophic Lateral Sclerosis	activates	disease	0.60
Multiple Sclerosis	interacts_with	disease	0.60
Stroke	expressed_in	disease	0.60
Neurodegeneration	associated_with	disease	0.60
Migraine	associated_with	disease	0.60
Ferroptosis	associated_with	disease	0.60
Neuroinflammation	inhibits	disease	0.60
Anxiety	activates	disease	0.60
Stroke	regulates	disease	0.60
Depression	therapeutic_target	disease	0.60
Epilepsy	therapeutic_target	disease	0.60
Huntington	activates	disease	0.60
Alzheimer	inhibits	disease	0.60
Epilepsy	inhibits	disease	0.60
Senescence	expressed_in	disease	0.60
Pyroptosis	causes	disease	0.60
Neurodegeneration	regulates	disease	0.60
Depression	associated_with	disease	0.60
Obesity	activates	disease	0.60
Epilepsy	activates	disease	0.60
Frontotemporal Dementia	activates	disease	0.60
Dementia	expressed_in	disease	0.60
Diabetes	associated_with	disease	0.60
Fibrosis	associated_with	disease	0.60
Obesity	associated_with	disease	0.60
Senescence	activates	disease	0.60
Lymphoma	activates	disease	0.60
Aging	therapeutic_target	disease	0.60

Incoming (474)

Source	Relation	Type	Str
GPR37	activates	gene	0.60
PARKINSON	activates	gene	0.60
PSAP	activates	gene	0.60
NRF2	activates	gene	0.60
STROKE	activates	gene	0.60
AMPK	activates	gene	0.60
CD68	activates	gene	0.60
CX3CR1	activates	gene	0.60
CXCL1	regulates	gene	0.60
IL-17	associated_with	gene	0.60
MMP9	regulates	gene	0.60
TNF	regulates	gene	0.60
JUN	regulates	gene	0.60
CXCL8	regulates	gene	0.60
TLR2	regulates	gene	0.60
IL-17	activates	gene	0.60
MMP9	activates	gene	0.60
BAX	activates	gene	0.60
S100A8	activates	gene	0.60
APOPTOSIS	activates	gene	0.60
S100A9	activates	gene	0.60
IL6	expressed_in	gene	0.60
HIF1	inhibits	gene	0.60
HIF1A	inhibits	gene	0.60
AGING	inhibits	gene	0.60
MICRORNAS	inhibits	gene	0.60
MIR-369-3P	inhibits	gene	0.60
RNA	therapeutic_target	gene	0.60
CYTOKINES	therapeutic_target	gene	0.60
IL-6	therapeutic_target	gene	0.60
GFAP	biomarker_for	gene	0.60
IL-1	biomarker_for	gene	0.60
CYTOKINES	biomarker_for	gene	0.60
IBA1	biomarker_for	gene	0.60
IL-6	biomarker_for	gene	0.60
MICROGLIA	therapeutic_target	gene	0.60
STROKE	therapeutic_target	gene	0.60
IL-33	activates	gene	0.60
TSLP	activates	gene	0.60
STROKE	biomarker_for	gene	0.60
ALZHEIMER	expressed_in	gene	0.60
SPG7	expressed_in	gene	0.60
DNA	expressed_in	gene	0.60
NDUFS8	expressed_in	gene	0.60
MAPT	expressed_in	gene	0.60
LDLR	expressed_in	gene	0.60
CLU	expressed_in	gene	0.60
IFNG	expressed_in	gene	0.60
IL-13	expressed_in	gene	0.60
NEURON	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning INTERLEUKIN in their description or question text

No additional research found