concept

ATP6AP2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ATP6AP2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

168Connections

0Hypotheses

0Analyses

50Outgoing

50Incoming

0Experiments

0Debates

Summary

ATP6AP2 is a concept in neurodegeneration research. Key relationships include: associated with, regulates, participates in. Associated with Cancer, Cardiovascular, Ischemia. Connected to 62 entities in the SciDEX knowledge graph.

View on Wiki →

No AI portrait yet

💡 Concept Info

Name	ATP6AP2
Key Genes/Proteins	Actin, AMBRA1, AMPK, AMYLOID, AND, APP
Related Diseases	Als
Related Pathways	Amyloid, Autophagy, autophagy pathway

Wiki Pages (1)

Knowledge base pages for this entity

ATP6AP2 (Renin Receptor) Protein

protein · 638 words

→

Pathway Diagram

graph TD
    ATP6AP2["ATP6AP2"]
    ATP6AP2 -->|"participates in"| lysosomal_acidification["lysosomal acidification"]
    ATP6AP2 -->|"regulates"| Cancer["Cancer"]
    ATP6AP2 -->|"regulates"| Cardiovascular["Cardiovascular"]
    ATP6AP2 -->|"regulates"| Neurodegeneration["Neurodegeneration"]

Outgoing (93)

Target	Relation	Type	Str
lysosomal acidification	participates_in	pathway	0.80
Cancer	regulates	disease	0.65
Cardiovascular	regulates	disease	0.65
Ischemia	associated_with	disease	0.65
Neurodegeneration	regulates	disease	0.65
Parkinson	associated_with	disease	0.65
Cardiovascular	associated_with	disease	0.65
Als	regulates	disease	0.65
Neurodegeneration	associated_with	disease	0.65
Cancer	associated_with	disease	0.65
Osteoclast	activates	cell_type	0.60
Actin	activates	protein	0.60
Osteoblast	regulates	cell_type	0.60
RANK	activates	gene	0.60
Wnt	regulates	pathway	0.60
Macrophage	activates	cell_type	0.60
ESR2	associated_with	gene	0.60
CYP19A1	associated_with	gene	0.60
RNA	associated_with	gene	0.60
UVRAG	associated_with	gene	0.60
AMBRA1	associated_with	gene	0.60
FYCO1	associated_with	gene	0.60
AMPK	associated_with	gene	0.60
AND	associated_with	gene	0.60
CTSD	associated_with	gene	0.60
GABA	associated_with	gene	0.60
ATG	associated_with	gene	0.60
ESR1	associated_with	gene	0.60
NEURODEGENERATION	associated_with	gene	0.60
PRESENILIN	associated_with	gene	0.60
ULK1	associated_with	gene	0.60
LAMP2	associated_with	gene	0.60
AMYLOID	associated_with	gene	0.60
YTHDF2	activates	gene	0.60
Amyloid	associated_with	pathway	0.60
Autophagy	associated_with	pathway	0.60
Mtor	associated_with	pathway	0.60
LC3B	associated_with	gene	0.60
PSEN2	associated_with	gene	0.60
CANCER	associated_with	gene	0.60
MTOR	associated_with	gene	0.60
GLA	associated_with	gene	0.60
APP	associated_with	gene	0.60
BCL2L1	associated_with	gene	0.60
Rb	associated_with	protein	0.60
Fus	associated_with	protein	0.60
HDAC6	associated_with	gene	0.60
PSEN1	associated_with	gene	0.60
MAP1LC3B	associated_with	gene	0.60
PIK3C3	associated_with	gene	0.60

Incoming (75)

Source	Relation	Type	Str
SOX9	associated_with	gene	0.60
MAP1LC3B	associated_with	gene	0.60
RAS	associated_with	gene	0.60
GABARAP	associated_with	gene	0.60
RAB9A	associated_with	gene	0.60
PIK3C3	associated_with	gene	0.60
AUTOPHAGY	associated_with	gene	0.60
VDAC2	associated_with	gene	0.60
WDR45	associated_with	gene	0.60
APP	activates	gene	0.60
AR	activates	gene	0.60
ATG	activates	gene	0.60
rapamycin	targets	drug	0.60
NEURODEGENERATION	associated_with	gene	0.60
BCL2L1	associated_with	gene	0.60
UVRAG	associated_with	gene	0.60
FYCO1	associated_with	gene	0.60
APP	associated_with	gene	0.60
LC3B	associated_with	gene	0.60
GLA	associated_with	gene	0.60
HDAC6	associated_with	gene	0.60
PRESENILIN	associated_with	gene	0.60
CANCER	associated_with	gene	0.60
CTSD	associated_with	gene	0.60
ATG	associated_with	gene	0.60
ESR1	associated_with	gene	0.60
PSEN2	associated_with	gene	0.60
AMYLOID	associated_with	gene	0.60
AMPK	associated_with	gene	0.60
LAMP2	associated_with	gene	0.60
MTOR	associated_with	gene	0.60
ESR2	associated_with	gene	0.60
ULK1	associated_with	gene	0.60
WNT	regulates	gene	0.60
RANKL	activates	gene	0.60
WNT3A	regulates	gene	0.60
CYP19A1	associated_with	gene	0.60
BCL2	associated_with	gene	0.60
RNA	associated_with	gene	0.60
GABA	associated_with	gene	0.60
TFEB	associated_with	gene	0.60
PSEN1	associated_with	gene	0.60
BECN1	associated_with	gene	0.60
AMBRA1	associated_with	gene	0.60
PRESENILIN	activates	protein	0.50
GABARAP	activates	protein	0.50
LC3B	activates	protein	0.50
ISCHEMIA	activates	disease	0.50
AMYLOID	activates	gene	0.50
disease	activates	disease	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning ATP6AP2 in their description or question text

No additional research found