gene

CNBP

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CNBP: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

39Connections

0Hypotheses

0Analyses

26Outgoing

13Incoming

0Experiments

0Debates

Summary

Comprehensive review of CNBP gene, a zinc-finger protein implicated in Myotonic Dystrophy Type 2 and neurodegenerative disease pathogenesis

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🧬 Gene Info

Gene Symbol	CNBP
Full Name	Cellular Nucleic Acid Binding Protein
Chromosome	3q21.3
Protein Family	CCHC-type zinc finger
Function	is a human gene located on chromosome 3q21.
Primary Expression	Skeletal muscle, Heart, Brain, Spinal cord
Amino Acids	182 aa
UniProt ID	Q9GZL0
NCBI Gene ID	28985
Ensembl ID	ENSG00000182021
OMIM	116955
GeneCards	CNBP
Human Protein Atlas	CNBP
Associated Diseases	ALS, Amyotrophic Lateral Sclerosis, frontotemporal dementia, Myotonic Dystrophy Type 2, Neurodegeneration, Parkinson's disease
KG Connections	39 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: CNBP — AlphaFold Q9GZL0 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

CNBP — Cellular Nucleic Acid Binding Protein

gene · 2009 words

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Pathway Diagram

graph TD
    CNBP["CNBP"]
    Als{"Als"}
    CNBP -->|"therapeutic target"| Als
    Ms{"Ms"}
    CNBP -->|"therapeutic target"| Ms
    MTDNA["MTDNA"]
    CNBP -->|"therapeutic target"| MTDNA
    Autophagy(["Autophagy"])
    CNBP -->|"therapeutic target"| Autophagy
    Mitophagy(["Mitophagy"])
    CNBP -->|"therapeutic target"| Mitophagy
    neurodegeneration["neurodegeneration"]
    CNBP -->|"implicated in"| neurodegeneration
    BNIP3["BNIP3"]
    BNIP3 -->|"therapeutic target"| CNBP
    MITOPHAGY["MITOPHAGY"]
    MITOPHAGY -->|"therapeutic target"| CNBP
    P62["P62"]
    P62 -->|"therapeutic target"| CNBP
    MITOCHONDRIAL_DNA["MITOCHONDRIAL DNA"]
    MITOCHONDRIAL_DNA -->|"therapeutic target"| CNBP
    MITOCHONDRIAL_DYSFUNCTION["MITOCHONDRIAL DYSFUNCTION"]
    MITOCHONDRIAL_DYSFUNCTION -->|"therapeutic target"| CNBP
    AUTOPHAGY["AUTOPHAGY"]
    AUTOPHAGY -->|"therapeutic target"| CNBP
    style CNBP fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (26)

Target	Relation	Type	Str
Myotonic Dystrophy Type 2	causes	disease	0.95
Ms	therapeutic_target	disease	0.65
Neurodegeneration	associated_with	disease	0.65
Als	therapeutic_target	disease	0.65
ALS	associated_with	disease	0.65
Tauopathy	associated_with	disease	0.65
Amyotrophic Lateral Sclerosis	associated_with	disease	0.65
AUTOPHAGY	therapeutic_target	gene	0.60
RNA	associated_with	gene	0.60
AND	associated_with	gene	0.60
NEURODEGENERATIVE DISEASES	associated_with	gene	0.60
NPC1	associated_with	gene	0.60
TAUOPATHY	associated_with	gene	0.60
frontotemporal dementia	associated_with	disease	0.60
Parkinson's disease	associated_with	disease	0.60
GAIN	associated_with	gene	0.60
RAN	associated_with	gene	0.60
DMPK	associated_with	gene	0.60
TAU	associated_with	gene	0.60
ZNF9/CNBP	associated_with	gene	0.60
NPC2	associated_with	gene	0.60
MTDNA	therapeutic_target	gene	0.60
Autophagy	therapeutic_target	pathway	0.60
Mitophagy	therapeutic_target	pathway	0.60
MITOCHONDRIAL DYSFUNCTION	therapeutic_target	gene	0.60
MITOPHAGY	therapeutic_target	gene	0.60

Incoming (13)

Source	Relation	Type	Str
BNIP3	therapeutic_target	gene	0.60
P62	therapeutic_target	gene	0.60
NEURODEGENERATION	associated_with	gene	0.60
GENES	associated_with	gene	0.60
AMYOTROPHIC LATERAL SCLEROSIS	associated_with	gene	0.60
MITOPHAGY	therapeutic_target	gene	0.60
MITOCHONDRIAL DNA	therapeutic_target	gene	0.60
MITOCHONDRIAL DYSFUNCTION	therapeutic_target	gene	0.60
AUTOPHAGY	therapeutic_target	gene	0.60
DNA	therapeutic_target	gene	0.60
MITOCHONDRIA	therapeutic_target	gene	0.60
MTDNA	therapeutic_target	gene	0.60
AND	therapeutic_target	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CNBP in their description or question text

No additional research found