concept

ONCOGENES

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ONCOGENES: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

163Connections

0Hypotheses

0Analyses

50Outgoing

50Incoming

0Experiments

0Debates

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💡 Concept Info

Name	ONCOGENES
Key Genes/Proteins	AGING, AKT, AND, APOPTOSIS, App, AUTOPHAGY
Related Diseases	Aging, Als, ALS
Related Pathways	Akt, Angiogenesis, Apoptosis, Autophagy

Pathway Diagram

graph TD
    ONCOGENES["ONCOGENES"]
    style ONCOGENES fill:#1a237e,stroke:#4fc3f7,stroke-width:3px
    ONCOGENES -->|"involved_in"| Carcinogenesis["Carcinogenesis"]
    ONCOGENES -->|"causes"| Hepatocellular_Carcinoma["Hepatocellular Carcinoma"]
    ONCOGENES -->|"interacts"| SWI_SNF([SWI/SNF])
    ONCOGENES -->|"activates"| Ms["Ms"]
    ONCOGENES -->|"activates"| Als["Als"]
    ONCOGENES -->|"activates"| Tumor["Tumor"]
    ONCOGENES -->|"activates"| Cancer["Cancer"]
    ONCOGENES -->|"activates"| Aging["Aging"]
    MET([MET]) -->|"activates"| ONCOGENES
    GENES([GENES]) -->|"activates"| ONCOGENES
    CANCER([CANCER]) -->|"activates"| ONCOGENES
    IGF2BP2([IGF2BP2]) -->|"activates"| ONCOGENES
    BRD4([BRD4]) -->|"activates"| ONCOGENES
    AGING([AGING]) -->|"activates"| ONCOGENES
    RNA([RNA]) -->|"expressed in"| ONCOGENES
    OPA1([OPA1]) -->|"activates"| ONCOGENES

Outgoing (113)

Target	Relation	Type	Str
Carcinogenesis	involved_in	process	0.93
Hepatocellular Carcinoma	causes	disease	0.85
SWI/SNF	interacts_with	protein	0.80
Cancer	expressed_in	disease	0.65
Cancer	causes	disease	0.65
ALS	activates	disease	0.65
Cirrhosis	activates	disease	0.65
Ms	therapeutic_target	disease	0.65
Cancer	activates	disease	0.65
Aging	activates	disease	0.65
Tumor	inhibits	disease	0.65
Cancer	inhibits	disease	0.65
Als	therapeutic_target	disease	0.65
Longevity	therapeutic_target	disease	0.65
Pain	therapeutic_target	disease	0.65
Cancer	therapeutic_target	disease	0.65
Aging	therapeutic_target	disease	0.65
Carcinoma	activates	disease	0.65
Cancer	associated_with	disease	0.65
Als	activates	disease	0.65
Ms	activates	disease	0.65
ALS	expressed_in	disease	0.65
Tumor	activates	disease	0.65
Carcinoma	causes	disease	0.65
ALS	causes	disease	0.65
Cancer	interacts_with	disease	0.65
Tumor	causes	disease	0.65
ALS	interacts_with	disease	0.65
KLF7	activates	gene	0.60
JUN	causes	gene	0.60
CANCER	causes	gene	0.60
Cytokine	activates	protein	0.60
Angiogenesis	activates	pathway	0.60
GENES	interacts_with	gene	0.60
CANCER	interacts_with	gene	0.60
HUB GENES	activates	gene	0.60
CCL2	activates	gene	0.60
Macrophage	activates	cell_type	0.60
CYTOKINES	activates	gene	0.60
GENES	activates	gene	0.60
Raf	therapeutic_target	protein	0.60
Rb	therapeutic_target	protein	0.60
App	therapeutic_target	protein	0.60
Raf	activates	protein	0.60
Igf	activates	protein	0.60
Ras	activates	protein	0.60
App	activates	protein	0.60
BRD4	activates	gene	0.60
IGF2BP2	activates	gene	0.60
PDGFRA	expressed_in	gene	0.60

Incoming (50)

Source	Relation	Type	Str
HCC	associated_with	disease	0.70
MET	activates	gene	0.60
GENES	activates	gene	0.60
CANCER	activates	gene	0.60
GENES	interacts_with	gene	0.60
CANCER	therapeutic_target	gene	0.60
IGF2BP2	activates	gene	0.60
BRD4	activates	gene	0.60
OPA1	activates	gene	0.60
AKT	activates	gene	0.60
CCL2	activates	gene	0.60
PDK1	activates	gene	0.60
GENES	inhibits	gene	0.60
TUMOR SUPPRESSOR GENES	inhibits	gene	0.60
PROTO-ONCOGENES	inhibits	gene	0.60
CYTOKINES	activates	gene	0.60
CYP3A4	activates	gene	0.60
P53	activates	gene	0.60
TUMOR SUPPRESSOR GENES	activates	gene	0.60
MTOR	activates	gene	0.60
CYP1A2	activates	gene	0.60
EGFR	activates	gene	0.60
CEBPB	activates	gene	0.60
PI3K	activates	gene	0.60
ERCC3	activates	gene	0.60
EGF	activates	gene	0.60
CANCER	inhibits	gene	0.60
KLF7	activates	gene	0.60
GENES	expressed_in	gene	0.60
AKT	causes	gene	0.60
AND	inhibits	gene	0.60
ROS	activates	gene	0.60
SREBP2	activates	gene	0.60
CANCER	associated_with	gene	0.60
DNM1L	activates	gene	0.60
DRP1	activates	gene	0.60
KRAS	activates	gene	0.60
RAS	associated_with	gene	0.60
VDAC1	activates	gene	0.60
DES	therapeutic_target	gene	0.60
APOPTOSIS	activates	gene	0.60
PDGFRA	expressed_in	gene	0.60
MYC	causes	gene	0.60
JUN	causes	gene	0.60
AGING	activates	gene	0.60
RNA	expressed_in	gene	0.60
CANCER	causes	gene	0.60
HUB GENES	activates	gene	0.60
MYCN	activates	gene	0.60
IRF2BP2	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning ONCOGENES in their description or question text

No additional research found