Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about KLF7: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | KLF7 |
| Key Genes/Proteins | AND, App, BRD4, CANCER, GENES, HUB GENES |
| Related Diseases | Aging, Als, ALS, Cancer, Carcinoma |
graph TD
KLF7["KLF7"]
KLF7 -->|"upregulates"| IGF2BP2["IGF2BP2"]
KLF7 -->|"activates"| Cancer["Cancer"]
KLF7 -->|"activates"| Aging["Aging"]
KLF7 -->|"activates"| Als["Als"]
KLF7 -->|"activates"| Carcinoma["Carcinoma"]
KLF7 -->|"activates"| Tumor["Tumor"]
KLF7 -->|"activates"| ALS["ALS"]
KLF7 -->|"activates"| ONCOGENES["ONCOGENES"]
BRD4["BRD4"] -->|"activates"| KLF7
GENES["GENES"] -->|"activates"| KLF7
IGF2BP2 -->|"activates"| KLF7
ONCOGENES -->|"activates"| KLF7
AND["AND"] -->|"activates"| KLF7
HUB_GENES["HUB GENES"] -->|"activates"| KLF7
CANCER["CANCER"] -->|"activates"| KLF7| Target | Relation | Type | Str |
|---|---|---|---|
| IGF2BP2 | upregulates | gene | 0.95 |
| IGF2BP2 | binds | gene | 0.93 |
| IGF2BP2 | correlates_with | gene | 0.88 |
| Poor Prognosis | associated_with | phenotype | 0.82 |
| ALS | activates | disease | 0.65 |
| Aging | activates | disease | 0.65 |
| Cancer | activates | disease | 0.65 |
| Als | activates | disease | 0.65 |
| Carcinoma | activates | disease | 0.65 |
| Tumor | activates | disease | 0.65 |
| App | activates | protein | 0.60 |
| AND | activates | gene | 0.60 |
| ONCOGENES | activates | gene | 0.60 |
| BRD4 | activates | gene | 0.60 |
| IGF2BP2 | activates | gene | 0.60 |
| CANCER | activates | gene | 0.60 |
| HUB GENES | activates | gene | 0.60 |
| GENES | activates | gene | 0.60 |
| Raf | activates | protein | 0.60 |
| Igf | activates | protein | 0.60 |
| Ras | activates | protein | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning KLF7 in their description or question text
No additional research found