concept

NBN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NBN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

59Connections

0Hypotheses

0Analyses

50Outgoing

2Incoming

0Experiments

0Debates

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💡 Concept Info

Name	NBN
Key Genes/Proteins	ALZHEIMER'S DISEASE, AND, APOPTOSIS, ATM, ATR, BAG1
Related Diseases	Als, Alzheimer, Ataxia, Cancer
Related Pathways	Apoptosis

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

NBN Gene

gene · 548 words

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NBS1 (NBN)

gene · 2573 words

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Pathway Diagram

graph TD
    NBN["NBN"]
    NBN -->|"regulates"| Cancer["Cancer"]
    NBN -->|"regulates"| Ataxia["Ataxia"]
    NBN -->|"regulates"| Dementia["Dementia"]
    NBN -->|"regulates"| Schizophrenia["Schizophrenia"]
    NBN -->|"regulates"| Alzheimer["Alzheimer"]
    NBN -->|"regulates"| Multiple_Sclerosis["Multiple Sclerosis"]
    NBN -->|"regulates"| Als["Als"]
    NBN -->|"regulates"| Ms["Ms"]
    NBN -->|"regulates"| BRIP1["BRIP1"]
    NBN -->|"regulates"| STK11["STK11"]
    ATM["ATM"] -->|"regulates"| NBN
    TP53["TP53"] -->|"regulates"| NBN

Outgoing (57)

Target	Relation	Type	Str
Alzheimer	regulates	disease	0.65
Multiple Sclerosis	regulates	disease	0.65
Als	regulates	disease	0.65
Ms	regulates	disease	0.65
Ataxia	regulates	disease	0.65
Cancer	regulates	disease	0.65
Dementia	regulates	disease	0.65
Schizophrenia	regulates	disease	0.65
Als	associated_with	disease	0.65
Infection	associated_with	disease	0.65
Ataxia	associated_with	disease	0.65
AND	associated_with	gene	0.60
ENDOSOME	associated_with	gene	0.60
MICROTUBULES	associated_with	gene	0.60
DNA	associated_with	gene	0.60
BRCA2	regulates	gene	0.60
SGK3	regulates	gene	0.60
TNF	regulates	gene	0.60
SLC24A2	regulates	gene	0.60
DNAJC2	regulates	gene	0.60
CHMP3	regulates	gene	0.60
PDE4C	regulates	gene	0.60
BAG1	regulates	gene	0.60
VTI1B	regulates	gene	0.60
EIF4G1	regulates	gene	0.60
NOX1	regulates	gene	0.60
NGF	regulates	gene	0.60
DISC1	regulates	gene	0.60
GALNT3	regulates	gene	0.60
IREB2	regulates	gene	0.60
TPX2	associated_with	gene	0.60
ATM	associated_with	gene	0.60
MDC1	associated_with	gene	0.60
ATR	associated_with	gene	0.60
MRE11	associated_with	gene	0.60
SYN1	associated_with	gene	0.60
CHEK1	associated_with	gene	0.60
CHMP6	associated_with	gene	0.60
EIF4EBP1	associated_with	gene	0.60
SLC2A1	associated_with	gene	0.60
CANCER	regulates	gene	0.60
CDH1	regulates	gene	0.60
ALZHEIMER'S DISEASE	regulates	gene	0.60
APOPTOSIS	regulates	gene	0.60
COMPLEMENT	regulates	gene	0.60
Apoptosis	regulates	pathway	0.60
Exocytosis	regulates	pathway	0.60
Mitochondrial Function	regulates	pathway	0.60
BRIP1	regulates	gene	0.60
Complement	regulates	pathway	0.60

Incoming (2)

Source	Relation	Type	Str
ATM	regulates	gene	0.60
TP53	regulates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning NBN in their description or question text

No additional research found