gene

SLC24A2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SLC24A2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

33Connections

0Hypotheses

0Analyses

25Outgoing

8Incoming

0Experiments

0Debates

Summary

Page for SLC24A2 — Solute Carrier Family 2 Member 4A2 (SLC24A2)

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🧬 Gene Info

Gene Symbol	SLC24A2
Full Name	Solute Carrier Family 2 Member 4A2 (SLC24A2)
Chromosome	9p21
Function	is a hallmark of many neurodegenerative diseases.
Primary Expression	the olfactory bulb, where it plays a critical role in olfactory receptor neuron function
Pathways	Apoptosis, Complement, Exocytosis, Mitochondrial Function
UniProt ID	O43295
NCBI Gene ID	8994
Ensembl ID	ENSG00000159339
OMIM	609521
GeneCards	SLC24A2
Human Protein Atlas	SLC24A2
Olfactory bulb	Involved in olfactory signal processing
Associated Diseases	neurodegeneration
Interactions	NGF, PDE4C
KG Connections	33 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: SLC24A2 — AlphaFold O43295 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

SLC24A2 — Solute Carrier Family 2 Member 4A2 (SLC24A2)

gene · 793 words

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Pathway Diagram

graph TD
    SLC24A2["SLC24A2"]
    Dementia{"Dementia"}
    SLC24A2 -->|"regulates"| Dementia
    Schizophrenia{"Schizophrenia"}
    SLC24A2 -->|"regulates"| Schizophrenia
    Alzheimer{"Alzheimer"}
    SLC24A2 -->|"regulates"| Alzheimer
    Multiple_Sclerosis{"Multiple Sclerosis"}
    SLC24A2 -->|"regulates"| Multiple_Sclerosis
    Als{"Als"}
    SLC24A2 -->|"regulates"| Als
    Cancer{"Cancer"}
    SLC24A2 -->|"regulates"| Cancer
    Ms{"Ms"}
    SLC24A2 -->|"regulates"| Ms
    APOPTOSIS["APOPTOSIS"]
    SLC24A2 -->|"regulates"| APOPTOSIS
    DNAJC2["DNAJC2"]
    SLC24A2 -->|"regulates"| DNAJC2
    CHMP3["CHMP3"]
    SLC24A2 -->|"regulates"| CHMP3
    PDE4C["PDE4C"]
    SLC24A2 -->|"activates"| PDE4C
    BAG1["BAG1"]
    SLC24A2 -->|"regulates"| BAG1
    NBN["NBN"]
    NBN -->|"regulates"| SLC24A2
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"regulates"| SLC24A2
    SGK3["SGK3"]
    SGK3 -->|"regulates"| SLC24A2
    TNF["TNF"]
    TNF -->|"regulates"| SLC24A2
    CANCER["CANCER"]
    CANCER -->|"regulates"| SLC24A2
    style SLC24A2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (25)

Target	Relation	Type	Str
Cancer	regulates	disease	0.65
Ms	regulates	disease	0.65
Dementia	regulates	disease	0.65
Schizophrenia	regulates	disease	0.65
Alzheimer	regulates	disease	0.65
Multiple Sclerosis	regulates	disease	0.65
Als	regulates	disease	0.65
Complement	regulates	pathway	0.60
COMPLEMENT	regulates	gene	0.60
Apoptosis	regulates	pathway	0.60
Exocytosis	regulates	pathway	0.60
Mitochondrial Function	regulates	pathway	0.60
APOPTOSIS	regulates	gene	0.60
DNAJC2	regulates	gene	0.60
CHMP3	regulates	gene	0.60
PDE4C	activates	gene	0.60
BAG1	regulates	gene	0.60
VTI1B	regulates	gene	0.60
EIF4G1	regulates	gene	0.60
NOX1	regulates	gene	0.60
NGF	activates	gene	0.60
DISC1	regulates	gene	0.60
GALNT3	regulates	gene	0.60
IREB2	regulates	gene	0.60
WEE1	implicated_in	gene	0.60

Incoming (8)

Source	Relation	Type	Str
ALZHEIMER'S DISEASE	regulates	gene	0.60
CANCER	regulates	gene	0.60
EFNB3	implicated_in	gene	0.60
EPHB6	implicated_in	gene	0.60
HMGB1	implicated_in	gene	0.60
NBN	regulates	gene	0.60
SGK3	regulates	gene	0.60
TNF	regulates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SLC24A2 in their description or question text

No additional research found