SciDEX — Ampk Signaling

Outgoing (55)

Target	Relation	Type	Str
neural stem cells	active_in	cell_type	0.90
neurons	active_in	cell_type	0.80
bone metabolism	regulates	process	0.75
microglia	active_in	cell_type	0.70
NF-kB signaling	crosstalk_with	pathway	0.70
autophagy pathway	crosstalk_with	pathway	0.70
ferroptosis	crosstalk_with	pathway	0.70
cGAS-STING	crosstalk_with	pathway	0.70
thalamus	active_in	brain_region	0.70
hypothalamus	active_in	brain_region	0.70
mitochondrial dynamics	crosstalk_with	pathway	0.60
cerebellum	active_in	brain_region	0.60
B cells	active_in	cell_type	0.60
ubiquitin-proteasome	crosstalk_with	pathway	0.60
macrophages	active_in	cell_type	0.60
unfolded protein response	crosstalk_with	pathway	0.60
pyroptosis	crosstalk_with	pathway	0.60
hippocampus	active_in	brain_region	0.60
TGF-beta signaling	crosstalk_with	pathway	0.60
PI3K-AKT-mTOR signaling	crosstalk_with	pathway	0.60
ASTROCYTES	associated_with	cell_type	0.50
Neuron	therapeutic_target	cell_type	0.50
LACTATE	associated_with	phenotype	0.50
Astrocyte	activates	cell_type	0.50
Neuron	activates	cell_type	0.50
Neuron	regulates	cell_type	0.50
CSF	associated_with	phenotype	0.50
BDNF	associated_with	gene	0.50
GFAP	associated_with	gene	0.50
GDNF	associated_with	gene	0.50
APP	associated_with	gene	0.50
TAU	associated_with	protein	0.50
SIRT6	associated_with	gene	0.50
CEREBELLUM	activates	concept	0.50
WHITE MATTER	associated_with	brain_region	0.50
HIPPOCAMPUS	associated_with	brain_region	0.50
GRAY MATTER	associated_with	brain_region	0.50
HUNTINGTON	associated_with	disease	0.50
PARKINSON	associated_with	disease	0.50
APOPTOSIS	associated_with	phenotype	0.50
ASTROCYTE	associated_with	cell_type	0.50
CYTOKINES	associated_with	phenotype	0.50
GLUTAMATE	associated_with	phenotype	0.50
STROKE	associated_with	disease	0.50
NEURON	associated_with	cell_type	0.50
ALS	associated_with	disease	0.50
AUTOPHAGY	associated_with	phenotype	0.45
ATM	associated_with	gene	0.45
ULK1	associated_with	gene	0.45
AKT	associated_with	gene	0.45

Incoming (319)

Source	Relation	Type	Str
AMPK	activates	gene	1.00
GENES	activates	gene	1.00
Als	activates	disease	1.00
ULK1	participates_in	gene	0.90
AMPK	participates_in	gene	0.90
AUTOPHAGY	activates	gene	0.90
Inflammation	activates	disease	0.90
Als	regulates	disease	0.90
lysosomal calcium channel dysfunction	associated_with	process	0.88
ATG	participates_in	gene	0.80
SIRT1	participates_in	gene	0.80
SQSTM1	participates_in	gene	0.80
BECN1	participates_in	gene	0.80
MTOR	participates_in	gene	0.80
aging	involves	disease	0.80
ATP	participates_in	gene	0.80
ROS	participates_in	gene	0.80
Fibrosis	activates	disease	0.80
CANCER	therapeutic_target	gene	0.80
SIRT1	activates	gene	0.80
INFLAMMATION	activates	gene	0.80
Cancer	therapeutic_target	disease	0.80
AMPK	therapeutic_target	gene	0.80
AMPK	regulates	gene	0.80
BRSK2	involved_in	protein	0.75
neurodegeneration	involves	disease	0.70
ATG5	activates	gene	0.70
LC3	participates_in	gene	0.70
TFEB	participates_in	gene	0.70
PIK3C3	participates_in	gene	0.70
HDAC6	participates_in	gene	0.70
LC3	activates	gene	0.70
AMPK	associated_with	gene	0.70
OXIDATIVE STRESS	activates	gene	0.70
APOPTOSIS	activates	gene	0.70
NEUROTOXICITY	activates	gene	0.70
MTOR	activates	gene	0.70
P62	activates	gene	0.70
AUTOPHAGY	regulates	gene	0.70
CANCER	activates	gene	0.70
Cancer	activates	disease	0.70
TNF-Α	activates	gene	0.70
MICROGLIA	activates	gene	0.70
RB1CC1	participates_in	gene	0.70
FIP200	participates_in	gene	0.70
Lung Cancer	activates	disease	0.70
IL-6	activates	gene	0.70
AMBRA1	participates_in	gene	0.70
LDL	participates_in	gene	0.70
TNF	activates	gene	0.70

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Title & PMID	Authors	Journal	Year	Citations
No papers found

Hypotheses and analyses mentioning Ampk Signaling in their description or question text

Name	Ampk Signaling
Key Genes/Proteins	AGING, Akt, AKT, AKT1, ALZHEIMER, ALZHEIMER'S DISEASE
Related Diseases	aging, Aging, Als, Alzheimer

Ampk Signaling

Understanding Entity Pages

Pathway Diagram

Outgoing (55)

Incoming (319)

Targeting Hypotheses (0)

Mentioning Analyses (0)

Experiments (0)

Related Papers (0)

Debates (0)

Related Research