concept

ADIPOQ

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ADIPOQ: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

60Connections

0Hypotheses

0Analyses

50Outgoing

4Incoming

0Experiments

0Debates

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💡 Concept Info

Name	ADIPOQ
Key Genes/Proteins	ACOX1, AKT1, AMPK, APP, ATG, BECN1
Related Pathways	autophagy pathway, complement cascade

Pathway Diagram

graph TD
    ADIPOQ[ADIPOQ]
    ADIPOQ -->|activates| BECN1[BECN1]
    ADIPOQ -->|activates| C1Q[C1Q]
    ADIPOQ -->|activates| FOXO1[FOXO1]
    ADIPOQ -->|activates| GLP1R[GLP1R]
    ADIPOQ -->|activates| GRK2[GRK2]
    ADIPOQ -->|activates| HTRA2[HTRA2]
    ADIPOQ -->|activates| KDM6B[KDM6B]
    ADIPOQ -->|activates| LAMP2[LAMP2]
    ADIPOQ -->|activates| LC3[LC3]
    ADIPOQ -->|activates| MAP3K5[MAP3K5]
    Niacin[Niacin] -->|upregulates| ADIPOQ
    ACOX1[ACOX1] -->|activates| ADIPOQ
    rapamycin[rapamycin] -->|targets| ADIPOQ
    benchmark_ot_ad_answer_key_ADI[benchmark_ot_ad_answer_key:ADIPOQ] -->|data_in| ADIPOQ

Outgoing (56)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:ADIPOQ	data_in	dataset_row	0.00
ATG	activates	gene	0.60
CREB	activates	gene	0.60
MAP1LC3	activates	gene	0.60
MTORC1	activates	gene	0.60
RAS	activates	gene	0.60
RUBCNL	activates	gene	0.60
SNARE	activates	gene	0.60
autophagy pathway	participates_in	pathway	0.60
GHRL	activates	gene	0.60
PTX3	activates	gene	0.60
TGF-beta signaling	participates_in	pathway	0.60
endothelial cells	expressed_in	cell_type	0.60
AKT1	regulates	gene	0.60
CDC42	regulates	gene	0.60
EGFR	regulates	gene	0.60
JAK2	regulates	gene	0.60
SNCA	regulates	gene	0.60
AMPK	activates	gene	0.60
neurodegeneration	regulates	disease	0.60
BECN1	activates	gene	0.60
C1Q	activates	gene	0.60
FOXO1	activates	gene	0.60
GLP1R	activates	gene	0.60
GRK2	activates	gene	0.60
HTRA2	activates	gene	0.60
KDM6B	activates	gene	0.60
LAMP2	activates	gene	0.60
LC3	activates	gene	0.60
MAP3K5	activates	gene	0.60
MTOR	activates	gene	0.60
NFE2L2	activates	gene	0.60
NOS3	activates	gene	0.60
NR1H3	activates	gene	0.60
PLIN2	activates	gene	0.60
PLIN3	activates	gene	0.60
PPARA	activates	gene	0.60
PRKAA2	activates	gene	0.60
RPTOR	activates	gene	0.60
SIRT1	activates	gene	0.60
SIRT3	activates	gene	0.60
SQSTM1	activates	gene	0.60
SREBF1	activates	gene	0.60
SREBF2	activates	gene	0.60
STING1	activates	gene	0.60
STX17	activates	gene	0.60
TFEB	activates	gene	0.60
TP53	activates	gene	0.60
ULK1	activates	gene	0.60
APP	activates	gene	0.60

Incoming (4)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:ADIPOQ	data_in	dataset_row	0.00
Niacin	upregulates	drug	0.85
ACOX1	activates	gene	0.60
rapamycin	targets	drug	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning ADIPOQ in their description or question text

No additional research found