gene

MIRNAS

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MIRNAS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

1731Connections

0Hypotheses

0Analyses

50Outgoing

50Incoming

0Experiments

0Debates

Summary

MIRNAS is a gene implicated in neurodegeneration research. Key relationships include: regulates, therapeutic target, associated with. Associated with ALS, Aging, Als. Connected to 1199 entities in the SciDEX knowledge graph.

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🧬 Gene Info

Gene Symbol	MIRNAS
Primary Expression	Ca1, Hippocampus, Prefrontal Cortex, Cortex, Thalamus
Pathways	Apoptosis, Immune Response, Oxidative Stress, Differentiation, Microrna
GeneCards	MIRNAS
Human Protein Atlas	MIRNAS
Associated Diseases	Aging, Als, Alzheimer, ALZHEIMERS_DISEASE, Amyotrophic Lateral Sclerosis
Interactions	ABCA1, ACSL4, Actin, AGING, AGO2, AKT
KG Connections	1712 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Pathway Diagram

graph TD
    MIRNAS["MIRNAS"] -->|"associated"| Cancer["Cancer"]
    MIRNAS["MIRNAS"] -.->|"inhibits"| Als["Als"]
    MIRNAS["MIRNAS"] -.->|"inhibits"| Tumor["Tumor"]
    MIRNAS["MIRNAS"] -->|"regulates"| Alzheimer["Alzheimer"]
    MIRNAS["MIRNAS"] -->|"activates"| Aging["Aging"]
    MIRNAS["MIRNAS"] -->|"activates"| Tumor_1["Tumor"]
    HNRNPA1["HNRNPA1"] -.->|"inhibits"| MIRNAS["MIRNAS"]
    GENES["GENES"] -->|"associated"| MIRNAS["MIRNAS"]
    LOX["LOX"] -->|"regulates"| MIRNAS["MIRNAS"]
    MICRORNAS["MICRORNAS"] -->|"activates"| MIRNAS["MIRNAS"]
    style MIRNAS fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (1306)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:MIRNAS	data_in	dataset_row	0.00
miRNAs	encodes	protein	0.00
Tumor	inhibits	disease	1.00
CANCER	therapeutic_target	gene	1.00
Lipid Metabolism	regulates	pathway	1.00
Immune Response	regulates	pathway	1.00
Als	inhibits	disease	1.00
Als	therapeutic_target	disease	1.00
Oxidative Stress	therapeutic_target	pathway	1.00
Als	regulates	disease	1.00
Cancer	regulates	disease	1.00
EXOSOMES	therapeutic_target	gene	1.00
Als	expressed_in	disease	1.00
Cancer	therapeutic_target	disease	1.00
Autoimmune	regulates	disease	1.00
Obesity	regulates	disease	1.00
Cancer	expressed_in	disease	1.00
Als	associated_with	disease	1.00
Breast Cancer	associated_with	disease	1.00
Inflammation	expressed_in	disease	1.00
Differentiation	regulates	pathway	1.00
Microrna	associated_with	pathway	1.00
Apoptosis	activates	pathway	1.00
MICRORNAS	associated_with	gene	1.00
Als	activates	disease	1.00
OXIDATIVE STRESS	therapeutic_target	gene	1.00
Tumor	activates	disease	1.00
GENES	activates	gene	1.00
Tumor	therapeutic_target	disease	1.00
GENES	associated_with	gene	1.00
Neuroinflammation	regulates	disease	1.00
Cancer	associated_with	disease	1.00
Cancer	activates	disease	1.00
Microrna	regulates	pathway	1.00
CANCER	associated_with	gene	1.00
OVERVIEW	regulates	gene	1.00
Microrna	expressed_in	pathway	1.00
Cancer	biomarker_for	disease	1.00
CANCER	regulates	gene	1.00
Aging	regulates	disease	1.00
Tumor	regulates	disease	1.00
INFLAMMATION	therapeutic_target	gene	1.00
MICRORNAS	therapeutic_target	gene	1.00
Epigenetic	regulates	pathway	1.00
Inflammation	regulates	disease	1.00
APOPTOSIS	activates	gene	1.00
Inflammation	activates	disease	1.00
Mapk	regulates	pathway	1.00
INFLAMMATION	regulates	gene	1.00
h-test-8d254307	targeted_by	hypothesis	1.00

Incoming (425)

Source	Relation	Type	Str
MIRNAS	encodes	gene	0.00
benchmark_ot_ad_answer_key:MIRNAS	data_in	dataset_row	0.00
h-test-8d254307	targets	hypothesis	1.00
h-test-full-8d254307	targets_gene	hypothesis	0.90
24957213	are involved in	paper	0.90
astrocytic ApoE	produces	protein	0.90
ApoE4	inhibits	protein	0.80
BCL2L11	targets	gene	0.80
ACUPUNCTURE	regulates	treatment	0.80
TP53	regulates	gene	0.70
ALZHEIMER'S DISEASE	regulates	gene	0.70
INFLAMMATION	regulates	gene	0.70
MICRORNAS	regulates	gene	0.70
GLUT4	therapeutic_target	gene	0.60
BACE1	therapeutic_target	gene	0.60
GENES	regulates	gene	0.60
OVERVIEW	activates	gene	0.60
GENES	activates	gene	0.60
RANK	therapeutic_target	gene	0.60
MAPK3	expressed_in	gene	0.60
BCL2	associated_with	gene	0.60
SMAD3	therapeutic_target	gene	0.60
RB1CC1	therapeutic_target	gene	0.60
FGF21	inhibits	gene	0.60
SIRT1	regulates	gene	0.60
NEURODEGENERATIVE DISEASES	regulates	gene	0.60
HNRNPA1	regulates	gene	0.60
SIGMAR1	regulates	gene	0.60
FAS	activates	gene	0.60
IL6	activates	gene	0.60
MOTOR NEURONS	expressed_in	gene	0.60
FN1	regulates	gene	0.60
PYROPTOSIS	regulates	gene	0.60
CASP1	associated_with	gene	0.60
SMAD2	inhibits	gene	0.60
BLOOD-BRAIN BARRIER DYSFUNCTION	inhibits	gene	0.60
ERK	expressed_in	gene	0.60
SIRT1	therapeutic_target	gene	0.60
ALZHEIMER'S DISEASE	therapeutic_target	gene	0.60
AUTOPHAGY	expressed_in	gene	0.60
CANCER	regulates	gene	0.60
MICRORNAS	inhibits	gene	0.60
EXOSOMES	regulates	gene	0.60
CANCER	interacts_with	gene	0.60
MICRORNAS	protects_against	gene	0.60
MICRORNAS	expressed_in	gene	0.60
CIRCADIAN RHYTHM	therapeutic_target	gene	0.60
MYC	expressed_in	gene	0.60
AKT	expressed_in	gene	0.60
FAS	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning MIRNAS in their description or question text

No additional research found