gene

MIRNAS

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MIRNAS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

1740Connections

0Hypotheses

0Analyses

50Outgoing

50Incoming

0Experiments

0Debates

Summary

MIRNAS is a gene implicated in neurodegeneration research. Key relationships include: regulates, therapeutic target, associated with. Associated with ALS, Aging, Als. Connected to 1199 entities in the SciDEX knowledge graph.

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🧬 Gene Info

Gene Symbol	MIRNAS
Primary Expression	Ca1, Hippocampus, Prefrontal Cortex, Cortex, Thalamus
Pathways	Apoptosis, Immune Response, Oxidative Stress, Differentiation, Microrna
GeneCards	MIRNAS
Human Protein Atlas	MIRNAS
Associated Diseases	Aging, Als, Alzheimer, ALZHEIMERS_DISEASE, Amyotrophic Lateral Sclerosis
Interactions	ABCA1, ACSL4, Actin, AGING, AGO2, AKT
KG Connections	1724 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Pathway Diagram

graph TD
    MIRNAS["MIRNAS"] -->|"associated"| Cancer["Cancer"]
    MIRNAS["MIRNAS"] -.->|"inhibits"| Als["Als"]
    MIRNAS["MIRNAS"] -.->|"inhibits"| Tumor["Tumor"]
    MIRNAS["MIRNAS"] -->|"regulates"| Alzheimer["Alzheimer"]
    MIRNAS["MIRNAS"] -->|"activates"| Aging["Aging"]
    MIRNAS["MIRNAS"] -->|"activates"| Tumor_1["Tumor"]
    HNRNPA1["HNRNPA1"] -.->|"inhibits"| MIRNAS["MIRNAS"]
    GENES["GENES"] -->|"associated"| MIRNAS["MIRNAS"]
    LOX["LOX"] -->|"regulates"| MIRNAS["MIRNAS"]
    MICRORNAS["MICRORNAS"] -->|"activates"| MIRNAS["MIRNAS"]
    style MIRNAS fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (1312)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:MIRNAS	data_in	dataset_row	0.00
Microrna	biomarker_for	pathway	1.00
Mapk	regulates	pathway	1.00
MICRORNAS	associated_with	gene	1.00
Als	inhibits	disease	1.00
CANCER	associated_with	gene	1.00
Lipid Metabolism	regulates	pathway	1.00
Als	associated_with	disease	1.00
Tumor	inhibits	disease	1.00
Cancer	associated_with	disease	1.00
MICRORNAS	expressed_in	gene	1.00
Microrna	associated_with	pathway	1.00
APOPTOSIS	therapeutic_target	gene	1.00
CANCER	activates	gene	1.00
Microrna	expressed_in	pathway	1.00
Als	expressed_in	disease	1.00
INFLAMMATION	therapeutic_target	gene	1.00
Epigenetic	regulates	pathway	1.00
Alzheimer	therapeutic_target	disease	1.00
Tumor	regulates	disease	1.00
Drug Resistance	therapeutic_target	pathway	1.00
APOPTOSIS	regulates	gene	1.00
GENES	regulates	gene	1.00
Inflammation	therapeutic_target	disease	1.00
Neuroinflammation	regulates	disease	1.00
Apoptosis	therapeutic_target	pathway	1.00
Differentiation	regulates	pathway	1.00
Obesity	regulates	disease	1.00
Oxidative Stress	therapeutic_target	pathway	1.00
Aging	therapeutic_target	disease	1.00
Cancer	expressed_in	disease	1.00
Inflammation	regulates	disease	1.00
EXOSOMES	therapeutic_target	gene	1.00
Microrna	therapeutic_target	pathway	1.00
Apoptosis	regulates	pathway	1.00
GENES	associated_with	gene	1.00
Autoimmune	regulates	disease	1.00
GENES	expressed_in	gene	1.00
Tumor	therapeutic_target	disease	1.00
Inflammation	expressed_in	disease	1.00
AUTOPHAGY	therapeutic_target	gene	1.00
Microrna	regulates	pathway	1.00
CANCER	regulates	gene	1.00
Immune Response	regulates	pathway	1.00
Cancer	biomarker_for	disease	1.00
Inflammation	activates	disease	1.00
CANCER	therapeutic_target	gene	1.00
Als	activates	disease	1.00
CANCER	biomarker_for	gene	1.00
MICRORNAS	therapeutic_target	gene	1.00

Incoming (428)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:MIRNAS	data_in	dataset_row	0.00
h-test-8d254307	targets	hypothesis	1.00
astrocytic ApoE	produces	protein	0.90
h-test-full-8d254307	targets_gene	hypothesis	0.90
ApoE4	inhibits	protein	0.80
BCL2L11	targets	gene	0.80
ACUPUNCTURE	regulates	treatment	0.80
INFLAMMATION	regulates	gene	0.70
MICRORNAS	regulates	gene	0.70
ALZHEIMER'S DISEASE	regulates	gene	0.70
TP53	regulates	gene	0.70
HIP1	therapeutic_target	gene	0.60
TGM2	therapeutic_target	gene	0.60
NRF1	therapeutic_target	gene	0.60
PVALB	interacts_with	gene	0.60
CAV1	regulates	gene	0.60
ZCWPW1	associated_with	gene	0.60
GAB2	associated_with	gene	0.60
CR1	associated_with	gene	0.60
RAS	biomarker_for	gene	0.60
NDUFA9	therapeutic_target	gene	0.60
MS4A4E	associated_with	gene	0.60
PICALM	associated_with	gene	0.60
CLU	associated_with	gene	0.60
APOE	associated_with	gene	0.60
BIN1	associated_with	gene	0.60
CD2AP	associated_with	gene	0.60
TOMM40	associated_with	gene	0.60
NME8	associated_with	gene	0.60
MECP2	contributes_to	gene	0.60
SMAD4	activates	gene	0.60
IL1B	activates	gene	0.60
IL18	activates	gene	0.60
TNF	activates	gene	0.60
P16	activates	gene	0.60
ALZHEIMER	biomarker_for	gene	0.60
MMP9	associated_with	gene	0.60
TLR4	associated_with	gene	0.60
ABCA7	associated_with	gene	0.60
IL10	associated_with	gene	0.60
CCL2	associated_with	gene	0.60
CXCL8	associated_with	gene	0.60
RAGE	associated_with	gene	0.60
IL6	associated_with	gene	0.60
EXOSOMES	therapeutic_target	gene	0.60
TNF	therapeutic_target	gene	0.60
GNAI3	therapeutic_target	gene	0.60
APP/PS1	therapeutic_target	gene	0.60
DNA	phosphorylates	gene	0.60
AUTOPHAGY-RELATED GENES	regulates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning MIRNAS in their description or question text

No additional research found