gene

MIRNAS

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MIRNAS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

1731Connections

0Hypotheses

0Analyses

50Outgoing

50Incoming

0Experiments

0Debates

Summary

MIRNAS is a gene implicated in neurodegeneration research. Key relationships include: regulates, therapeutic target, associated with. Associated with ALS, Aging, Als. Connected to 1199 entities in the SciDEX knowledge graph.

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🧬 Gene Info

Gene Symbol	MIRNAS
Primary Expression	Ca1, Hippocampus, Prefrontal Cortex, Cortex, Thalamus
Pathways	Apoptosis, Immune Response, Oxidative Stress, Differentiation, Microrna
GeneCards	MIRNAS
Human Protein Atlas	MIRNAS
Associated Diseases	Aging, Als, Alzheimer, ALZHEIMERS_DISEASE, Amyotrophic Lateral Sclerosis
Interactions	ABCA1, ACSL4, Actin, AGING, AGO2, AKT
KG Connections	1712 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Pathway Diagram

graph TD
    MIRNAS["MIRNAS"] -->|"associated"| Cancer["Cancer"]
    MIRNAS["MIRNAS"] -.->|"inhibits"| Als["Als"]
    MIRNAS["MIRNAS"] -.->|"inhibits"| Tumor["Tumor"]
    MIRNAS["MIRNAS"] -->|"regulates"| Alzheimer["Alzheimer"]
    MIRNAS["MIRNAS"] -->|"activates"| Aging["Aging"]
    MIRNAS["MIRNAS"] -->|"activates"| Tumor_1["Tumor"]
    HNRNPA1["HNRNPA1"] -.->|"inhibits"| MIRNAS["MIRNAS"]
    GENES["GENES"] -->|"associated"| MIRNAS["MIRNAS"]
    LOX["LOX"] -->|"regulates"| MIRNAS["MIRNAS"]
    MICRORNAS["MICRORNAS"] -->|"activates"| MIRNAS["MIRNAS"]
    style MIRNAS fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (1306)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:MIRNAS	data_in	dataset_row	0.00
miRNAs	encodes	protein	0.00
Als	expressed_in	disease	1.00
CANCER	regulates	gene	1.00
MICRORNAS	expressed_in	gene	1.00
APOPTOSIS	regulates	gene	1.00
EXOSOMES	therapeutic_target	gene	1.00
Tumor	regulates	disease	1.00
Als	associated_with	disease	1.00
Epigenetic	regulates	pathway	1.00
Inflammation	regulates	disease	1.00
Apoptosis	regulates	pathway	1.00
Inflammation	activates	disease	1.00
Microrna	expressed_in	pathway	1.00
CANCER	therapeutic_target	gene	1.00
GENES	expressed_in	gene	1.00
Als	activates	disease	1.00
Cancer	regulates	disease	1.00
Tumor	activates	disease	1.00
Cancer	activates	disease	1.00
Als	regulates	disease	1.00
GENES	therapeutic_target	gene	1.00
GENES	associated_with	gene	1.00
Als	inhibits	disease	1.00
Immune Response	regulates	pathway	1.00
AKT	therapeutic_target	gene	1.00
GENES	regulates	gene	1.00
GENES	activates	gene	1.00
Tumor	inhibits	disease	1.00
Neuroinflammation	regulates	disease	1.00
Lipid Metabolism	regulates	pathway	1.00
Apoptosis	activates	pathway	1.00
Cancer	expressed_in	disease	1.00
Microrna	biomarker_for	pathway	1.00
PI3K	therapeutic_target	gene	1.00
Cholesterol	regulates	pathway	1.00
Als	therapeutic_target	disease	1.00
MICRORNAS	regulates	gene	1.00
CANCER	biomarker_for	gene	1.00
INFLAMMATION	regulates	gene	1.00
Differentiation	regulates	pathway	1.00
Cancer	biomarker_for	disease	1.00
Microrna	regulates	pathway	1.00
APOPTOSIS	therapeutic_target	gene	1.00
AUTOPHAGY	therapeutic_target	gene	1.00
Microrna	associated_with	pathway	1.00
Oxidative Stress	therapeutic_target	pathway	1.00
Inflammation	expressed_in	disease	1.00
Mapk	regulates	pathway	1.00
Cancer	therapeutic_target	disease	1.00

Incoming (425)

Source	Relation	Type	Str
MIRNAS	encodes	gene	0.00
benchmark_ot_ad_answer_key:MIRNAS	data_in	dataset_row	0.00
h-test-8d254307	targets	hypothesis	1.00
24957213	are involved in	paper	0.90
h-test-full-8d254307	targets_gene	hypothesis	0.90
astrocytic ApoE	produces	protein	0.90
ApoE4	inhibits	protein	0.80
ACUPUNCTURE	regulates	treatment	0.80
BCL2L11	targets	gene	0.80
TP53	regulates	gene	0.70
MICRORNAS	regulates	gene	0.70
ALZHEIMER'S DISEASE	regulates	gene	0.70
INFLAMMATION	regulates	gene	0.70
HNRNPA1	activates	gene	0.60
LOX	activates	gene	0.60
MAPK3	expressed_in	gene	0.60
CANCER	regulates	gene	0.60
SIRT1	regulates	gene	0.60
P53	regulates	gene	0.60
CTCF	regulates	gene	0.60
CD4	associated_with	gene	0.60
PYROPTOSIS	associated_with	gene	0.60
FERROPTOSIS	regulates	gene	0.60
RANK	expressed_in	gene	0.60
PHAGOCYTOSIS	associated_with	gene	0.60
HDAC6	activates	gene	0.60
FOXO1	regulates	gene	0.60
VIRAL INFECTIONS	associated_with	gene	0.60
ROS	inhibits	gene	0.60
VDR	regulates	gene	0.60
NF-KB	regulates	gene	0.60
ALOX15	regulates	gene	0.60
TP53	activates	gene	0.60
AGING	expressed_in	gene	0.60
GENES	expressed_in	gene	0.60
GENES	inhibits	gene	0.60
INFLAMMATION	therapeutic_target	gene	0.60
OVERVIEW	expressed_in	gene	0.60
P21	regulates	gene	0.60
SMAD2	expressed_in	gene	0.60
BMP2	associated_with	gene	0.60
MYC	associated_with	gene	0.60
TGFBR1	associated_with	gene	0.60
BMP7	associated_with	gene	0.60
PIK3R3	therapeutic_target	gene	0.60
PIK3CB	therapeutic_target	gene	0.60
PI3K	associated_with	gene	0.60
AKT3	therapeutic_target	gene	0.60
MALAT1	interacts_with	gene	0.60
NEURODEGENERATIVE DISEASES	therapeutic_target	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning MIRNAS in their description or question text

No additional research found