concept

SNF

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SNF: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

57Connections

0Hypotheses

0Analyses

22Outgoing

35Incoming

0Experiments

0Debates

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💡 Concept Info

Name	SNF
Key Genes/Proteins	ADNP, ASC, ATG, ATG16L1, ATP, BECN1
Related Diseases	autism spectrum disorder, cancer
Related Pathways	autophagy pathway, blood-brain barrier
Linked Hypotheses	1 hypotheses

Wiki Pages (1)

Knowledge base pages for this entity

SMARCB1 — SWI/SNF Related Matrix Associated Actin Dependent Regulator of Chromatin Subfamily B Member 1

gene · 1352 words

→

Pathway Diagram

graph TD
    SNF[SNF]
    SNF -->|interacts| SWI[SWI]
    SNF -->|activates| SQSTM1[SQSTM1]
    SNF -->|activates| STAT3[STAT3]
    SNF -->|activates| TNF[TNF]
    SNF -->|activates| TNFA[TNFA]
    SNF -->|activates| ULK1[ULK1]
    SNF -->|activates| cancer[cancer]
    SNF -->|causes| VHL[VHL]
    ASC[ASC] -->|activates| SNF
    BECN1[BECN1] -->|activates| SNF
    BRG1[BRG1] -->|activates| SNF
    CLDN2[CLDN2] -->|activates| SNF
    ERN1[ERN1] -->|activates| SNF
    IRGM1[IRGM1] -->|activates| SNF
    LC3[LC3] -->|activates| SNF
    MELK[MELK] -->|activates| SNF
    MTOR[MTOR] -->|activates| SNF
    NLRP3[NLRP3] -->|activates| SNF

Outgoing (22)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:SNF	data_in	dataset_row	0.00
SWI	interacts_with	gene	0.70
SWI	targets	gene	0.60
oxidative stress response	participates_in	pathway	0.60
necroptosis	participates_in	pathway	0.60
MAPK signaling	participates_in	pathway	0.60
PI3K-AKT-mTOR signaling	participates_in	pathway	0.60
autism spectrum disorder	interacts_with	disease	0.60
TJP1	activates	gene	0.60
blood-brain barrier	participates_in	pathway	0.60
cancer	activates	disease	0.60
autophagy pathway	participates_in	pathway	0.60
VHL	causes	gene	0.60
cancer	causes	disease	0.60
SQSTM1	activates	gene	0.60
STAT3	activates	gene	0.60
SWI	activates	gene	0.60
TNF	activates	gene	0.60
TNFA	activates	gene	0.60
ULK1	activates	gene	0.60
SWI	causes	gene	0.60
stem cells	expressed_in	cell_type	0.55

Incoming (35)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:SNF	data_in	dataset_row	0.00
CCDC50	activates	gene	0.60
IKK	activates	gene	0.60
MAP1LC3	activates	gene	0.60
MAPK	activates	gene	0.60
ATG	activates	gene	0.60
NRBF2	activates	gene	0.60
rapamycin	targets	drug	0.60
ROS	activates	gene	0.60
NLR	activates	gene	0.60
ATG16L1	activates	gene	0.60
LAMP1	activates	gene	0.60
ATP	activates	gene	0.60
LC3B	activates	gene	0.60
RNA	activates	gene	0.60
ASC	activates	gene	0.60
BECN1	activates	gene	0.60
BRG1	activates	gene	0.60
CLDN2	activates	gene	0.60
ERN1	activates	gene	0.60
IRGM1	activates	gene	0.60
LC3	activates	gene	0.60
MELK	activates	gene	0.60
MTOR	activates	gene	0.60
NLRP3	activates	gene	0.60
NOD2	activates	gene	0.60
PI3K	activates	gene	0.60
PYCARD	activates	gene	0.60
RALGAPA2	activates	gene	0.60
RIPK2	activates	gene	0.60
RIPK3	activates	gene	0.60
SMARCA4	activates	gene	0.60
ADNP	interacts_with	gene	0.60
PBRM1	causes	gene	0.60
RAPAMYCIN	associated_with	drug	0.45

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SNF in their description or question text

No additional research found