SciDEX — PREFRONTAL CORTEX

graph TD
    PREFRONTAL_CORTEX["PREFRONTAL CORTEX"]
    PREFRONTAL_CORTEX -->|"interacts"| Cognition["Cognition"]
    PREFRONTAL_CORTEX -->|"treats"| depression["depression"]
    Cognition -->|"interacts"| PREFRONTAL_CORTEX
    TMS["TMS"] -->|"regulates"| PREFRONTAL_CORTEX
    BDNF["BDNF"] -->|"expressed in"| PREFRONTAL_CORTEX
    PER["PER"] -->|"expressed in"| PREFRONTAL_CORTEX
    CANCER["CANCER"] -->|"expressed in"| PREFRONTAL_CORTEX
    CNO["CNO"] -->|"expressed in"| PREFRONTAL_CORTEX
    PHAGOCYTOSIS["PHAGOCYTOSIS"] -->|"expressed in"| PREFRONTAL_CORTEX
    HSPA1A["HSPA1A"] -->|"expressed in"| PREFRONTAL_CORTEX
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"] -->|"expressed in"| PREFRONTAL_CORTEX
    MICROGLIA["MICROGLIA"] -->|"expressed in"| PREFRONTAL_CORTEX

Outgoing (99)

Target	Relation	Type	Str
Cognitive Impairment	associated_with	phenotype	0.90
cortical inhibition	mediates	process	0.85
mood regulation	regulates	process	0.85
emotional processing	mediates	process	0.85
Brain Age	involved_in	biomarker	0.80
depression	treats	disease	0.70
Cognition	activates	entity	0.70
Cognition	interacts_with	entity	0.70
Cognition	inhibits	entity	0.70
Cognition	associated_with	entity	0.70
SUBSTANTIA NIGRA	causes	brain_region	0.65
TET2	associated_with	gene	0.50
TH	associated_with	gene	0.50
INTERNEURONS	activates	concept	0.50
INTERNEURONS	inhibits	concept	0.50
NUCLEUS	expressed_in	concept	0.50
NEUROGENESIS	associated_with	phenotype	0.50
GABA	associated_with	phenotype	0.50
NUCLEUS	inhibits	concept	0.50
SEROTONIN	activates	concept	0.50
AMYGDALA	associated_with	concept	0.50
NUCLEUS	associated_with	concept	0.50
GENE EXPRESSION	inhibits	concept	0.50
GRAY MATTER	interacts_with	concept	0.50
GRAY MATTER	associated_with	concept	0.50
PURKINJE CELLS	associated_with	cell_type	0.50
FRONTAL	activates	concept	0.50
GENE EXPRESSION	expressed_in	concept	0.50
NUCLEUS	regulates	concept	0.50
Proteins	regulates	protein	0.50
AMYGDALA	regulates	concept	0.50
PSILOCYBIN	associated_with	drug	0.45
INTERNEURONS	associated_with	cell_type	0.45
CHRNA7	associated_with	gene	0.45
HMGB1	associated_with	gene	0.45
TLR4	associated_with	gene	0.45
IBA1	associated_with	gene	0.45
OLIGODENDROCYTES	associated_with	cell_type	0.45
OLIGODENDROCYTE	associated_with	cell_type	0.45
TBK1	associated_with	gene	0.45
CHOLESTEROL	associated_with	phenotype	0.45
LEWY BODIES	associated_with	phenotype	0.45
BACE1	associated_with	gene	0.45
GRN	associated_with	gene	0.45
TMEM119	associated_with	gene	0.45
FERROPTOSIS	associated_with	phenotype	0.45
GLUTAMATE	associated_with	phenotype	0.45
BIPOLAR DISORDER	associated_with	disease	0.45
SEROTONIN	associated_with	phenotype	0.45
ACETYLCHOLINE	associated_with	phenotype	0.45

Incoming (336)

Source	Relation	Type	Str
ALZHEIMER'S DISEASE	associated_with	disease	1.00
parvalbumin-positive interneurons	expressed_in	cell_type	0.90
Psychedelics	modulates	compound	0.90
depression	affects	disease	0.90
NECL1	expressed_in	gene	0.85
resistance exercise	associated_with	process	0.85
PARKINSON'S DISEASE	associated_with	disease	0.82
ASTROCYTES	associated_with	cell_type	0.82
NECL1	expressed_in	gene	0.80
NLRP3	expressed_in	protein	0.80
RNA	expressed_in	gene	0.80
aerobic exercise	modulates	process	0.75
Engeletin	targets	compound	0.75
AMYLOID	associated_with	protein	0.74
MICROGLIA	associated_with	cell_type	0.74
BDNF	associated_with	gene	0.74
unfolded protein response	active_in	pathway	0.70
dopamine receptor	expressed_in	receptor	0.70
AMPA receptor	expressed_in	receptor	0.70
anxiety	affects	disease	0.70
BDNF	expressed_in	protein	0.70
serotonin	active_in	neurotransmitter	0.70
Cognition	associated_with	entity	0.70
Cognition	interacts_with	entity	0.70
APP	regulates	gene	0.70
INFLAMMATION	activates	phenotype	0.70
TMS	regulates	process	0.70
INFLAMMATION	causes	phenotype	0.70
neurodegeneration	affects	disease	0.70
CORTEX	contributes_to	brain_region	0.65
DEPRESSION	regulates	disease	0.65
HIPPOCAMPUS	contributes_to	brain_region	0.65
APOPTOSIS	regulates	phenotype	0.65
CORTEX	impairs	brain_region	0.65
NEURONS	causes	cell_type	0.65
C9ORF72	regulates	gene	0.65
FERROPTOSIS	causes	phenotype	0.65
DRD2	mediates	gene	0.65
CORTEX	causes	brain_region	0.65
BDNF	phosphorylates	gene	0.65
CORTEX	mediates	brain_region	0.65
NEURON	contributes_to	cell_type	0.65
CORTEX	targets	brain_region	0.65
CORTEX	biomarker_for	brain_region	0.65
DOPAMINERGIC	causes	cell_type	0.65
CORTEX	transports	brain_region	0.65
TAU	associated_with	protein	0.64
autism	affects	disease	0.60
GFAP	expressed_in	gene	0.60
glutamate receptor	expressed_in	receptor	0.60

Name	PREFRONTAL CORTEX
Key Genes/Proteins	ABCA1, ABCA7, ADAM10, AKT, ALZHEIMER, AMPK
Related Diseases	acetylcholine, ACETYLCHOLINE, aging, AGING, ALS

PREFRONTAL CORTEX

Understanding Entity Pages

Pathway Diagram

Outgoing (99)

Incoming (336)

Targeting Hypotheses (0)

Mentioning Analyses (0)

Experiments (0)

Related Papers (0)

Debates (0)