concept

NECL1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NECL1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

13Connections

0Hypotheses

0Analyses

12Outgoing

1Incoming

0Experiments

0Debates

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💡 Concept Info

Name	NECL1
Key Genes/Proteins	ADRA2A
Related Diseases	Dendritic Spine Loss, depression, Major Depressive Disorder

Pathway Diagram

graph TD
    NECL1[NECL1]
    NECL1 -->|regulates| synaptic_formation_and_functio[synaptic formation and function]
    NECL1 -->|regulates| Synaptic_Formation_And_Functio[Synaptic Formation And Function]
    NECL1 -->|regulates| Norepinephrine[Norepinephrine]
    NECL1 -->|regulates| ADRA2A[ADRA2A]
    NECL1 -->|regulates| norepinephrine[norepinephrine]
    NECL1 -->|involved_in| Major_Depressive_Disorder[Major Depressive Disorder]
    NECL1 -->|causes| Dendritic_Spine_Loss[Dendritic Spine Loss]
    NECL1 -->|regulates| Emotional_Processing[Emotional Processing]
    NECL1 -->|expressed in| Prefrontal_Cortex[Prefrontal Cortex]
    NECL1 -->|expressed in| prefrontal_cortex[prefrontal cortex]
    benchmark_ot_ad_answer_key_NEC[benchmark_ot_ad_answer_key:NECL1] -->|data_in| NECL1

Outgoing (12)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:NECL1	data_in	dataset_row	0.00
synaptic formation and function	regulates	process	0.95
Synaptic Formation And Function	regulates	process	0.95
Norepinephrine	regulates	compound	0.95
ADRA2A	regulates	gene	0.95
Major Depressive Disorder	involved_in	disease	0.90
Dendritic Spine Loss	causes	phenotype	0.90
norepinephrine	regulates	compound	0.90
Prefrontal Cortex	expressed_in	brain_region	0.85
Emotional Processing	regulates	process	0.85
prefrontal cortex	expressed_in	brain_region	0.80
depression	implicated_in	disease	0.60

Incoming (1)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:NECL1	data_in	dataset_row	0.00

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity