concept

BASAL GANGLIA

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about BASAL GANGLIA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

156Connections

0Hypotheses

0Analyses

50Outgoing

50Incoming

0Experiments

0Debates

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💡 Concept Info

Name	BASAL GANGLIA
Key Genes/Proteins	ACHE, AMYLOID, ATP13A2
Related Diseases	ASTROGLIOSIS, CANCER

Pathway Diagram

graph TD
    BASAL_GANGLIA["BASAL GANGLIA"]
    BASAL_GANGLIA -->|"expressed in"| HUNTINGTON["HUNTINGTON"]
    BASAL_GANGLIA -->|"expressed in"| HUNTINGTON_S["HUNTINGTON'S"]
    BASAL_GANGLIA -->|"causes"| CANCER["CANCER"]
    BASAL_GANGLIA -->|"impairs"| PARKIN["PARKIN"]
    BASAL_GANGLIA -->|"impairs"| PARKINSON["PARKINSON"]
    BASAL_GANGLIA -->|"impairs"| PARKINSON_S["PARKINSON'S"]
    BASAL_GANGLIA -->|"impairs"| PARKINSON_S_DISEASE["PARKINSON'S DISEASE"]
    BASAL_GANGLIA -->|"impairs"| SYNAPTIC_TRANSMISSION["SYNAPTIC TRANSMISSION"]
    zona_incerta["zona incerta"] -->|"interacts"| BASAL_GANGLIA
    ACHE["ACHE"] -->|"causes"| BASAL_GANGLIA
    OCLN["OCLN"] -->|"expressed in"| BASAL_GANGLIA
    GENES["GENES"] -->|"expressed in"| BASAL_GANGLIA
    XPR1["XPR1"] -->|"expressed in"| BASAL_GANGLIA
    SLC20A2["SLC20A2"] -->|"expressed in"| BASAL_GANGLIA
    PDGFRB["PDGFRB"] -->|"expressed in"| BASAL_GANGLIA
    PDGFB["PDGFB"] -->|"expressed in"| BASAL_GANGLIA

Outgoing (66)

Target	Relation	Type	Str
FRONTOTEMPORAL DEMENTIA	causes	disease	0.70
HUNTINGTON'S	expressed_in	disease	0.65
HUNTINGTON	expressed_in	disease	0.65
WHITE MATTER	activates	brain_region	0.65
SYNAPTIC TRANSMISSION	associated_with	biological_process	0.60
PARKIN	associated_with	gene	0.60
PARKINSON	associated_with	disease	0.60
PARKINSON'S DISEASE	associated_with	disease	0.60
CANCER	causes	disease	0.60
PARKINSON'S	impairs	disease	0.60
WHITE MATTER	regulates	brain_region	0.50
DRD2	associated_with	gene	0.50
SNCA	associated_with	gene	0.50
NEURON	associated_with	cell_type	0.50
STROKE	associated_with	disease	0.50
DOPAMINE	associated_with	phenotype	0.50
DEMENTIA	associated_with	disease	0.50
SEEDING	co_discussed	entity	0.50
THALAMUS	co_discussed	entity	0.50
MULTIPLE SCLEROSIS	co_discussed	entity	0.50
HYPOTHALAMUS	co_discussed	entity	0.50
CEREBELLUM	co_discussed	entity	0.50
TAU	co_discussed	entity	0.50
PYRAMIDAL	co_discussed	entity	0.50
PREFRONTAL	co_discussed	entity	0.50
STRIATUM	co_discussed	entity	0.50
PSP	co_discussed	entity	0.50
PARKINSON	co_discussed	entity	0.50
HIPPOCAMPUS	co_discussed	entity	0.50
CYTOKINE	co_discussed	entity	0.50
EPILEPSY	co_discussed	entity	0.50
PARKINSON'S	co_discussed	entity	0.50
CORTEX	co_discussed	entity	0.50
GPX4	co_discussed	entity	0.50
CBD	co_discussed	entity	0.50
NEURON	co_discussed	entity	0.50
GLUTAMATE	co_discussed	entity	0.50
GLUTAMATERGIC	co_discussed	entity	0.50
MYELINATION	co_discussed	entity	0.50
NEURODEGENERATION	co_discussed	entity	0.50
DOPAMINERGIC	co_discussed	entity	0.50
SUBSTANTIA NIGRA	co_discussed	entity	0.50
GABA	co_discussed	entity	0.50
GABAergic	co_discussed	entity	0.50
SYNAPTIC PLASTICITY	co_discussed	entity	0.50
NEURONS	co_discussed	entity	0.50
AMYLOID	associated_with	protein	0.45
NRF2	associated_with	gene	0.45
ATP13A2	associated_with	gene	0.45
TH	associated_with	gene	0.45

Incoming (90)

Source	Relation	Type	Str
Primary Familial Brain Calcification	associated_with	disease	0.95
manganese	associated_with	process	0.70
zona incerta	interacts_with	brain_region	0.70
Parkinson's disease	affects	disease	0.70
neurodegeneration	affects	disease	0.70
SUBSTANTIA NIGRA	causes	brain_region	0.65
PARKINSON'S DISEASE	degrades	disease	0.65
neuroinflammation	affects	disease	0.60
epilepsy	affects	disease	0.60
GJA1	expressed_in	gene	0.60
ACHE	causes	gene	0.60
Huntington's disease	affects	disease	0.60
PDGFRB	expressed_in	gene	0.55
OCLN	expressed_in	gene	0.55
PDGFB	expressed_in	gene	0.55
NLRP3	expressed_in	gene	0.55
GENES	expressed_in	gene	0.55
C1Q	expressed_in	gene	0.55
HUNTINGTIN	expressed_in	gene	0.55
Addiction	associated_with	disease	0.55
XPR1	expressed_in	gene	0.55
SLC20A2	expressed_in	gene	0.55
EPILEPSY	expressed_in	gene	0.55
MITOCHONDRIAL DYSFUNCTION	expressed_in	gene	0.55
PARKINSON'S DISEASE	expressed_in	gene	0.55
PARKINSON	expressed_in	gene	0.55
NEUROINFLAMMATION	expressed_in	gene	0.55
IFN	expressed_in	gene	0.55
IFN-Γ	expressed_in	gene	0.55
COMPLEMENT	expressed_in	gene	0.55
HUNTINGTON'S DISEASE	expressed_in	gene	0.55
HUNTINGTON	expressed_in	gene	0.55
FLT1	expressed_in	gene	0.55
MICROGLIA	expressed_in	gene	0.55
IL1B	expressed_in	gene	0.55
PVALB	expressed_in	gene	0.55
TAU	expressed_in	gene	0.55
SYNAPSE	expressed_in	gene	0.55
STAT1	expressed_in	gene	0.55
AND	expressed_in	gene	0.55
INFLAMMATION	expressed_in	gene	0.55
DEPRESSION	expressed_in	gene	0.55
IL-6	expressed_in	gene	0.55
CANCER	expressed_in	gene	0.55
LRRK2	expressed_in	gene	0.55
GABA	expressed_in	gene	0.55
Schizophrenia	associated_with	disease	0.55
SLC16A1	expressed_in	gene	0.55
ALZHEIMER	expressed_in	gene	0.55
ASTROCYTES	expressed_in	gene	0.55

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning BASAL GANGLIA in their description or question text

No additional research found