Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CBD: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | CBD |
| Key Genes/Proteins | amyloid-β |
| Related Diseases | Alzheimer's disease |
Knowledge base pages for this entity
graph TD
CBD[CBD]
CBD -->|treats| glioma[glioma]
CBD -->|activates| TRPV4[TRPV4]
CBD -->|interacts| temozolomide[temozolomide]
CBD -->|inhibits| amyloid__[amyloid-β]
CBD -->|regulates| tau_protein[tau protein]
CBD -->|treats| Alzheimer_s_disease[Alzheimer's disease]
CBD -->|activates| mitochondrial_dysfunction[mitochondrial dysfunction]
CBD -->|activates| PINK1[PINK1]| Target | Relation | Type | Str |
|---|---|---|---|
| Alzheimer's disease | treats | disease | 0.70 |
| mitochondrial dysfunction | activates | process | 0.70 |
| glioma | treats | disease | 0.70 |
| TRPV4 | activates | protein | 0.70 |
| temozolomide | interacts_with | drug | 0.70 |
| amyloid-β | inhibits | protein | 0.70 |
| tau protein | regulates | protein | 0.70 |
| DLB | co_discussed | entity | 0.50 |
| CEREBELLUM | co_discussed | entity | 0.50 |
| PURKINJE | co_discussed | entity | 0.50 |
| SYNAPSE | co_discussed | entity | 0.50 |
| NEURODEGENERATION | co_discussed | entity | 0.50 |
| PARKINSON'S | co_discussed | entity | 0.50 |
| OLIGODENDROCYTE | co_discussed | entity | 0.50 |
| OLIGODENDROCYTES | co_discussed | entity | 0.50 |
| SUBSTANTIA NIGRA | co_discussed | entity | 0.50 |
| GLUTAMATE | co_discussed | entity | 0.50 |
| SEEDING | co_discussed | entity | 0.50 |
| TDP-43 | co_discussed | entity | 0.50 |
| CORTEX | co_discussed | entity | 0.50 |
| DEMENTIA | co_discussed | entity | 0.50 |
| FRONTOTEMPORAL | co_discussed | entity | 0.50 |
| MICROGLIA | co_discussed | entity | 0.50 |
| NEUROINFLAMMATION | co_discussed | entity | 0.50 |
| EPILEPSY | co_discussed | entity | 0.50 |
| FTD | co_discussed | entity | 0.50 |
| MONOCYTE | co_discussed | entity | 0.50 |
| MONOCYTES | co_discussed | entity | 0.50 |
| INFLAMMASOME | co_discussed | entity | 0.50 |
| CYTOKINE | co_discussed | entity | 0.50 |
| NEURON | co_discussed | entity | 0.50 |
| NEURONS | co_discussed | entity | 0.50 |
| TAU | co_discussed | entity | 0.50 |
| MSA | co_discussed | entity | 0.50 |
| MAPT | co_discussed | entity | 0.50 |
| STING | co_discussed | entity | 0.50 |
| PINK1 | co_discussed | entity | 0.50 |
| PINK1 | activates | entity | 0.50 |
| MITOCHONDRIA | co_discussed | entity | 0.50 |
| PARKINSON | co_discussed | entity | 0.50 |
| PSP | co_discussed | entity | 0.50 |
| Source | Relation | Type | Str |
|---|---|---|---|
| BDNF | co_discussed | entity | 0.50 |
| APOPTOSIS | co_discussed | entity | 0.50 |
| ASTROCYTE | co_discussed | entity | 0.50 |
| ASTROCYTES | co_discussed | entity | 0.50 |
| C9ORF72 | co_discussed | entity | 0.50 |
| BASAL GANGLIA | co_discussed | entity | 0.50 |
| BRAINSTEM | co_discussed | entity | 0.50 |
| ALZHEIMER | co_discussed | entity | 0.50 |
| ALZHEIMER'S | co_discussed | entity | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-01 | 7 hypotheses Top: 0.732
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 0.69 · 2026-04-12
closed · Rounds: 7 · Score: 0.91 · 2026-04-10
Hypotheses and analyses mentioning CBD in their description or question text
No additional research found