Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about TNFRSF19: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | TNFRSF19 |
| Key Genes/Proteins | ABCB1, ALDH1A1, AND, App, ATF3, AXIN2 |
| Related Diseases | Als, ALS, Atherosclerosis |
| Related Pathways | Cholesterol |
graph TD
TNFRSF19["TNFRSF19"]
TNFRSF19 -.biomarker for.-> Coronary_Artery_Disease["Coronary Artery Disease"]
TNFRSF19 -.biomarker for.-> Atherosclerosis["Atherosclerosis"]
TNFRSF19 -.biomarker for.-> Fibrosis["Fibrosis"]
TNFRSF19 -.biomarker for.-> ALS["ALS"]
TNFRSF19 -.biomarker for.-> Inflammation["Inflammation"]
TNFRSF19 -.biomarker for.-> Als["Als"]
TNFRSF19 -.biomarker for.-> NTS["NTS"]
TNFRSF19 -.biomarker for.-> GENES["GENES"]
NR4A2["NR4A2"] -.biomarker for.-> TNFRSF19
MMP9["MMP9"] -.biomarker for.-> TNFRSF19
MSR1["MSR1"] -.biomarker for.-> TNFRSF19
HTR3C["HTR3C"] -.biomarker for.-> TNFRSF19
IL1A["IL1A"] -.biomarker for.-> TNFRSF19
LDLR["LDLR"] -.biomarker for.-> TNFRSF19
IL13RA1["IL13RA1"] -.biomarker for.-> TNFRSF19
CXCL2["CXCL2"] -.biomarker for.-> TNFRSF19| Target | Relation | Type | Str |
|---|---|---|---|
| Coronary Artery Disease | biomarker_for | disease | 0.90 |
| Atherosclerosis | biomarker_for | disease | 0.65 |
| Fibrosis | biomarker_for | disease | 0.65 |
| Als | biomarker_for | disease | 0.65 |
| ALS | biomarker_for | disease | 0.65 |
| Inflammation | biomarker_for | disease | 0.65 |
| CSF2 | biomarker_for | gene | 0.60 |
| STAT3 | biomarker_for | gene | 0.60 |
| MMP9 | biomarker_for | gene | 0.60 |
| LDLR | biomarker_for | gene | 0.60 |
| RNA | biomarker_for | gene | 0.60 |
| AND | biomarker_for | gene | 0.60 |
| IL1A | biomarker_for | gene | 0.60 |
| CXCL2 | biomarker_for | gene | 0.60 |
| JAK1 | biomarker_for | gene | 0.60 |
| CCR9 | biomarker_for | gene | 0.60 |
| MSR1 | biomarker_for | gene | 0.60 |
| Immune Response | biomarker_for | pathway | 0.60 |
| NR4A2 | biomarker_for | gene | 0.60 |
| Cholesterol | biomarker_for | pathway | 0.60 |
| App | biomarker_for | protein | 0.60 |
| VEGFA | targets | gene | 0.60 |
| NTS | biomarker_for | gene | 0.60 |
| GENES | biomarker_for | gene | 0.60 |
| HTR3C | biomarker_for | gene | 0.60 |
| INFLAMMATION | biomarker_for | gene | 0.60 |
| IL13RA1 | biomarker_for | gene | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| NR4A2 | biomarker_for | gene | 0.60 |
| IL13RA1 | biomarker_for | gene | 0.60 |
| MMP9 | biomarker_for | gene | 0.60 |
| MSR1 | biomarker_for | gene | 0.60 |
| HTR3C | biomarker_for | gene | 0.60 |
| IL1A | biomarker_for | gene | 0.60 |
| LDLR | biomarker_for | gene | 0.60 |
| CXCL2 | biomarker_for | gene | 0.60 |
| RNA | biomarker_for | gene | 0.60 |
| NTS | biomarker_for | gene | 0.60 |
| CSF2 | biomarker_for | gene | 0.60 |
| CCR9 | biomarker_for | gene | 0.60 |
| ABCB1 | targets | gene | 0.60 |
| ALDH1A1 | targets | gene | 0.60 |
| ATF3 | targets | gene | 0.60 |
| AXIN2 | targets | gene | 0.60 |
| BAMBI | targets | gene | 0.60 |
| CCND1 | targets | gene | 0.60 |
| CD44 | targets | gene | 0.60 |
| CLDN1 | targets | gene | 0.60 |
| CTLA4 | targets | gene | 0.60 |
| DKK1 | targets | gene | 0.60 |
| EOMES | targets | gene | 0.60 |
| FGF18 | targets | gene | 0.60 |
| FGF20 | targets | gene | 0.60 |
| FZD7 | targets | gene | 0.60 |
| IL10 | targets | gene | 0.60 |
| JAG1 | targets | gene | 0.60 |
| LEF1 | targets | gene | 0.60 |
| MITF | targets | gene | 0.60 |
| MYC | targets | gene | 0.60 |
| NEUROD1 | targets | gene | 0.60 |
| NOTCH2 | targets | gene | 0.60 |
| NRCAM | targets | gene | 0.60 |
| PPARD | targets | gene | 0.60 |
| PTGS2 | targets | gene | 0.60 |
| SNAI1 | targets | gene | 0.60 |
| TERT | targets | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning TNFRSF19 in their description or question text
No additional research found