HTR3C

Understanding Entity Pages

This page aggregates everything SciDEX knows about HTR3C: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

The HTR3C gene encodes the 5-HT3 receptor subunit C, a ligand-gated ion channel component that modulates receptor properties in peripheral and central nervous system. This page covers the gene's structure, function, expression, disease associations, and therapeutic relevance.

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graph TD
    HTR3C["HTR3C"]
    Inflammation{"Inflammation"}
    HTR3C -->|"biomarker for"| Inflammation
    Als{"Als"}
    HTR3C -->|"biomarker for"| Als
    Atherosclerosis{"Atherosclerosis"}
    HTR3C -->|"biomarker for"| Atherosclerosis
    Ms{"Ms"}
    HTR3C -->|"biomarker for"| Ms
    Fibrosis{"Fibrosis"}
    HTR3C -->|"biomarker for"| Fibrosis
    ALS{"ALS"}
    HTR3C -->|"biomarker for"| ALS
    NTS["NTS"]
    HTR3C -->|"biomarker for"| NTS
    IL1A["IL1A"]
    HTR3C -->|"biomarker for"| IL1A
    LDLR["LDLR"]
    HTR3C -->|"biomarker for"| LDLR
    Cholesterol(["Cholesterol"])
    HTR3C -->|"biomarker for"| Cholesterol
    Immune_Response(["Immune Response"])
    HTR3C -->|"biomarker for"| Immune_Response
    IL13RA1["IL13RA1"]
    HTR3C -->|"biomarker for"| IL13RA1
    NR4A2["NR4A2"]
    NR4A2 -->|"biomarker for"| HTR3C
    CXCL2["CXCL2"]
    CXCL2 -->|"biomarker for"| HTR3C
    CSF2["CSF2"]
    CSF2 -->|"biomarker for"| HTR3C
    MSR1["MSR1"]
    MSR1 -->|"biomarker for"| HTR3C
    STAT3["STAT3"]
    STAT3 -->|"biomarker for"| HTR3C
    MMP9["MMP9"]
    MMP9 -->|"biomarker for"| HTR3C
    JAK1["JAK1"]
    JAK1 -->|"biomarker for"| HTR3C
    IL1A -->|"biomarker for"| HTR3C
    LDLR -->|"biomarker for"| HTR3C
    GENES["GENES"]
    GENES -->|"biomarker for"| HTR3C
    style HTR3C fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

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