Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ALBUMIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No summary available yet.
No AI portrait yet
| Name | ALBUMIN |
Knowledge base pages for this entity
graph TD
ALBUMIN["ALBUMIN"]
style ALBUMIN fill:#1a237e,stroke:#4fc3f7,stroke-width:3px
ALBUMIN -->|"regulates"| Ischemia["Ischemia"]
ALBUMIN -->|"encodes"| Aging["Aging"]
ALBUMIN -->|"encodes"| Neurodegeneration["Neurodegeneration"]
ALBUMIN -->|"encodes"| Als["Als"]
ALBUMIN -->|"activates"| Stroke["Stroke"]
ALBUMIN -->|"interacts"| Cancer["Cancer"]
ALBUMIN -.->|"inhibits"| Alzheimer["Alzheimer"]
ALBUMIN -.->|"protects against"| Diabetes["Diabetes"]
PPARG([PPARG]) -->|"regulates"| ALBUMIN
PPARGC1A([PPARGC1A]) -->|"regulates"| ALBUMIN
MITOCHONDRIA([MITOCHONDRIA]) -->|"activates"| ALBUMIN
SREBF1([SREBF1]) -->|"regulates"| ALBUMIN
LAMP1([LAMP1]) -->|"regulates"| ALBUMIN
EIF4EBP1([EIF4EBP1]) -->|"regulates"| ALBUMIN
CTSD([CTSD]) -->|"regulates"| ALBUMIN
NADH([NADH]) -->|"regulates"| ALBUMIN
ACTB([ACTB]) -->|"regulates"| ALBUMIN
RAS([RAS]) -->|"regulates"| ALBUMIN| Target | Relation | Type | Str |
|---|---|---|---|
| Glycocalyx Degradation | inhibits | process | 0.85 |
| glycocalyx degradation | suppresses | process | 0.70 |
| Neuroinflammation | associated_with | disease | 0.60 |
| Parkinson | regulates | disease | 0.60 |
| Als | inhibits | disease | 0.60 |
| Dementia | biomarker_for | disease | 0.60 |
| Neuroinflammation | biomarker_for | disease | 0.60 |
| Alzheimer | biomarker_for | disease | 0.60 |
| Als | causes | disease | 0.60 |
| Aging | biomarker_for | disease | 0.60 |
| Aging | activates | disease | 0.60 |
| Diabetes | protects_against | disease | 0.60 |
| Als | biomarker_for | disease | 0.60 |
| Diabetes | biomarker_for | disease | 0.60 |
| Anxiety | regulates | disease | 0.60 |
| Depression | activates | disease | 0.60 |
| Dementia | regulates | disease | 0.60 |
| Neurodegeneration | regulates | disease | 0.60 |
| Neuroinflammation | regulates | disease | 0.60 |
| Alzheimer | regulates | disease | 0.60 |
| Autism | interacts_with | disease | 0.60 |
| Neurodegeneration | activates | disease | 0.60 |
| Alzheimer | associated_with | disease | 0.60 |
| Autism | associated_with | disease | 0.60 |
| Epilepsy | associated_with | disease | 0.60 |
| Autism | activates | disease | 0.60 |
| Schizophrenia | activates | disease | 0.60 |
| Alzheimer | expressed_in | disease | 0.60 |
| Anxiety | activates | disease | 0.60 |
| Alzheimer | activates | disease | 0.60 |
| Aging | encodes | disease | 0.60 |
| Neurodegeneration | encodes | disease | 0.60 |
| Als | encodes | disease | 0.60 |
| Ischemia | regulates | disease | 0.60 |
| Stroke | activates | disease | 0.60 |
| Anxiety | associated_with | disease | 0.60 |
| Depression | associated_with | disease | 0.60 |
| Als | associated_with | disease | 0.60 |
| Cancer | interacts_with | disease | 0.60 |
| Als | interacts_with | disease | 0.60 |
| Alzheimer | inhibits | disease | 0.60 |
| Fibrosis | associated_with | disease | 0.60 |
| Epilepsy | therapeutic_target | disease | 0.60 |
| Alzheimer | encodes | disease | 0.60 |
| Als | therapeutic_target | disease | 0.60 |
| Als | expressed_in | disease | 0.60 |
| Aging | regulates | disease | 0.60 |
| Schizophrenia | regulates | disease | 0.60 |
| Autism | regulates | disease | 0.60 |
| Neurodegeneration | expressed_in | disease | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| PPARG | regulates | gene | 0.60 |
| PPARGC1A | regulates | gene | 0.60 |
| MITOCHONDRIA | activates | gene | 0.60 |
| SREBF1 | regulates | gene | 0.60 |
| LAMP1 | regulates | gene | 0.60 |
| EIF4EBP1 | regulates | gene | 0.60 |
| CTSD | regulates | gene | 0.60 |
| NADH | regulates | gene | 0.60 |
| ACTB | regulates | gene | 0.60 |
| RAS | regulates | gene | 0.60 |
| CPT1A | regulates | gene | 0.60 |
| RAB7A | regulates | gene | 0.60 |
| ELAVL2 | encodes | gene | 0.60 |
| SNAP29 | encodes | gene | 0.60 |
| FUS | encodes | gene | 0.60 |
| TDP-43 | encodes | gene | 0.60 |
| STX17 | encodes | gene | 0.60 |
| RAB5 | inhibits | gene | 0.60 |
| CLPP | encodes | gene | 0.60 |
| BDNF | encodes | gene | 0.60 |
| ALS | encodes | gene | 0.60 |
| IGF2BP1 | encodes | gene | 0.60 |
| MAPK | encodes | gene | 0.60 |
| RAB11 | inhibits | gene | 0.60 |
| YTHDF1 | encodes | gene | 0.60 |
| AUTOPHAGY | encodes | gene | 0.60 |
| METTL3 | encodes | gene | 0.60 |
| AMYLOID | inhibits | gene | 0.60 |
| ALZHEIMER | inhibits | gene | 0.60 |
| NRG1 | associated_with | gene | 0.60 |
| DEPRESSION | associated_with | gene | 0.60 |
| ANXIETY | associated_with | gene | 0.60 |
| RNA | protects_against | gene | 0.60 |
| APOPTOSIS | activates | gene | 0.60 |
| PER | biomarker_for | gene | 0.60 |
| CATALASE | biomarker_for | gene | 0.60 |
| MIRNAS | biomarker_for | gene | 0.60 |
| MICRORNAS | biomarker_for | gene | 0.60 |
| EGFR | associated_with | gene | 0.60 |
| JUN | activates | gene | 0.60 |
| NEURON | activates | gene | 0.60 |
| BDNF | activates | gene | 0.60 |
| STROKE | activates | gene | 0.60 |
| MTOR | activates | gene | 0.60 |
| CCL4 | activates | gene | 0.60 |
| LC3 | inhibits | gene | 0.60 |
| AUTOPHAGY | activates | gene | 0.60 |
| ALZHEIMER | encodes | gene | 0.60 |
| RNA | therapeutic_target | gene | 0.60 |
| EPILEPSY | therapeutic_target | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Closed-loop tACS targeting EC-II parvalbumin interneurons to | 0.831 | Alzheimer's disease | Circuit-level neural dynamics in neurode |
| Parvalbumin Interneuron Vulnerability Links Lactate Transpor | 0.656 | neurodegeneration | What is the molecular mechanism by which |
| TYRO3-STAT1 Axis to Preserve Parvalbumin Interneuron Functio | 0.506 | neuroinflammation | Why do TAM receptors protect against neu |
| APOE4 astrocytes fail to supply sufficient cholesterol to pa | 0.500 | neuroscience | APOE4-driven lipid metabolism dysregulat |
| Human Serum Albumin-Mediated Displacement Creates False-Posi | 0.136 | molecular biology | Does Alectinib truly bind C1q directly w |
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning ALBUMIN in their description or question text
No additional research found