concept

TFCP2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about TFCP2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

191Connections

0Hypotheses

0Analyses

50Outgoing

50Incoming

0Experiments

0Debates

No summary available yet.

View on Wiki →

No AI portrait yet

💡 Concept Info

Name	TFCP2
Key Genes/Proteins	A2M, ABCA1, ABCA2, ACE, ALZHEIMER, ALZHEIMER'S DISEASE
Related Diseases	Als, ALS, Alzheimer, Alzheimer's disease
Related Pathways	Amyloid

Pathway Diagram

graph TD
    TFCP2["TFCP2"]
    style TFCP2 fill:#1a237e,stroke:#4fc3f7,stroke-width:3px
    TFCP2 -->|"regulates"| Alzheimer_s_Disease_Susceptibi["Alzheimer's Disease Susceptibility Genes"]
    TFCP2 -->|"regulates"| Alzheimer["Alzheimer"]
    TFCP2 -->|"interacts"| Tumor["Tumor"]
    TFCP2 -->|"interacts"| ALS["ALS"]
    TFCP2 -->|"interacts"| Als["Als"]
    TFCP2 -->|"regulates"| Atherosclerosis["Atherosclerosis"]
    Hsv_1["Hsv-1"] -->|"binds"| TFCP2
    IL6([IL6]) -->|"interacts"| TFCP2
    APOE([APOE]) -->|"interacts"| TFCP2
    NCSTN([NCSTN]) -->|"interacts"| TFCP2
    PSEN2([PSEN2]) -->|"interacts"| TFCP2
    IL1B([IL1B]) -->|"interacts"| TFCP2
    DAPK1([DAPK1]) -->|"interacts"| TFCP2
    APH1B([APH1B]) -->|"interacts"| TFCP2
    FAS([FAS]) -->|"interacts"| TFCP2
    MAPT([MAPT]) -->|"interacts"| TFCP2

Outgoing (105)

Target	Relation	Type	Str
Alzheimer's Disease Susceptibility Genes	regulates	process	0.80
Alzheimer	degrades	disease	0.65
Als	degrades	disease	0.65
Atherosclerosis	degrades	disease	0.65
Atherosclerosis	transports	disease	0.65
Alzheimer	transports	disease	0.65
ALS	transports	disease	0.65
Alzheimer	encodes	disease	0.65
Alzheimer	associated_with	disease	0.65
Als	regulates	disease	0.65
Atherosclerosis	regulates	disease	0.65
Tumor	interacts_with	disease	0.65
ALS	interacts_with	disease	0.65
Alzheimer	regulates	disease	0.65
Als	interacts_with	disease	0.65
APP	interacts_with	gene	0.60
MAPT	interacts_with	gene	0.60
APH1B	interacts_with	gene	0.60
FAS	interacts_with	gene	0.60
AND	regulates	gene	0.60
ALZHEIMER'S DISEASE	regulates	gene	0.60
DAPK1	interacts_with	gene	0.60
PSEN1	interacts_with	gene	0.60
APOPTOSIS	interacts_with	gene	0.60
PEN2	interacts_with	gene	0.60
GENES	regulates	gene	0.60
DNA	interacts_with	gene	0.60
ALZHEIMER	regulates	gene	0.60
EIF2AK2	interacts_with	gene	0.60
SREBF1	interacts_with	gene	0.60
PARP1	interacts_with	gene	0.60
DHCR24	interacts_with	gene	0.60
A2M	interacts_with	gene	0.60
LMNA	interacts_with	gene	0.60
Apoptosis	interacts_with	pathway	0.60
Amyloid	interacts_with	pathway	0.60
PSEN2	interacts_with	gene	0.60
IL6	interacts_with	gene	0.60
Cholesterol	interacts_with	pathway	0.60
APOC2	regulates	gene	0.60
SOAT1	regulates	gene	0.60
ABCA2	regulates	gene	0.60
PSEN2	regulates	gene	0.60
TAU	regulates	gene	0.60
LDLR	regulates	gene	0.60
APOC3	regulates	gene	0.60
Cholesterol	regulates	pathway	0.60
Neuron	regulates	cell_type	0.60
LIPA	degrades	gene	0.60
AMYLOID	interacts_with	gene	0.60

Incoming (86)

Source	Relation	Type	Str
Hsv-1	binds	entity	0.85
HSV-1	binds	entity	0.80
NCSTN	interacts_with	gene	0.60
PSEN2	interacts_with	gene	0.60
IL1B	interacts_with	gene	0.60
LIPA	regulates	gene	0.60
APP	regulates	gene	0.60
APOE	regulates	gene	0.60
CYP46A1	regulates	gene	0.60
ABCA1	regulates	gene	0.60
NCSTN	regulates	gene	0.60
APOD	regulates	gene	0.60
GSK3B	regulates	gene	0.60
PSEN1	regulates	gene	0.60
SREBF1	regulates	gene	0.60
APOC1	regulates	gene	0.60
DNA	interacts_with	gene	0.60
AMYLOID	interacts_with	gene	0.60
ACE	interacts_with	gene	0.60
BACE1	interacts_with	gene	0.60
BDNF	interacts_with	gene	0.60
IDE	interacts_with	gene	0.60
IL10	interacts_with	gene	0.60
PLAU	interacts_with	gene	0.60
SORL1	interacts_with	gene	0.60
APOE	interacts_with	gene	0.60
DAPK1	interacts_with	gene	0.60
APH1B	interacts_with	gene	0.60
FAS	interacts_with	gene	0.60
MAPT	interacts_with	gene	0.60
PARP1	interacts_with	gene	0.60
A2M	interacts_with	gene	0.60
APOPTOSIS	interacts_with	gene	0.60
DHCR24	interacts_with	gene	0.60
ALZHEIMER	regulates	gene	0.60
APP	interacts_with	gene	0.60
HMGCR	interacts_with	gene	0.60
DYNEIN	interacts_with	gene	0.60
EIF2AK2	interacts_with	gene	0.60
PEN2	interacts_with	gene	0.60
LMNA	interacts_with	gene	0.60
TNF	interacts_with	gene	0.60
PSEN1	interacts_with	gene	0.60
SREBF1	interacts_with	gene	0.60
HSPG2	interacts_with	gene	0.60
APOE	transports	gene	0.60
PSEN2	regulates	gene	0.60
LIPA	transports	gene	0.60
LDLR	transports	gene	0.60
APOD	degrades	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning TFCP2 in their description or question text

No additional research found