Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CELL MIGRATION: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | CELL MIGRATION |
| Key Genes/Proteins | AKT, AQP4, EGFR |
| Related Diseases | atherosclerosis, ATHEROSCLEROSIS, BREAST CANCER, cancer, CANCER |
| Related Pathways | Egfr Signaling |
Knowledge base pages for this entity
graph TD
CELL_MIGRATION["CELL MIGRATION"]
CELL_MIGRATION -->|"contributes to"| Wound_Healing["Wound Healing"]
CELL_MIGRATION -->|"accumulates_in"| INFLAMMATION["INFLAMMATION"]
CELL_MIGRATION -->|"activates"| TUMOR["TUMOR"]
CELL_MIGRATION -->|"interacts"| LRP1["LRP1"]
CELL_MIGRATION -->|"implicated in"| NEURON["NEURON"]
CELL_MIGRATION -->|"regulates"| NEUROINFLAMMATION["NEUROINFLAMMATION"]
CELL_MIGRATION -->|"activates"| EGFR["EGFR"]
ABLIM1["ABLIM1"] -->|"promotes"| CELL_MIGRATION
PSME2["PSME2"] -->|"inhibits"| CELL_MIGRATION
Aloperine["Aloperine"] -->|"inhibits"| CELL_MIGRATION
Chrysotoxine["Chrysotoxine"] -->|"inhibits"| CELL_MIGRATION
PI3K_AKT["PI3K/AKT"] -->|"promotes"| CELL_MIGRATION
MAPK["MAPK"] -->|"regulates"| CELL_MIGRATION
Cinobufagin["Cinobufagin"] -->|"inhibits"| CELL_MIGRATION
OCLN["OCLN"] -->|"inhibits"| CELL_MIGRATION| Target | Relation | Type | Str |
|---|---|---|---|
| Wound Healing | contributes_to | process | 0.95 |
| CELL PROLIFERATION | regulates | phenotype | 0.65 |
| GLYCOLYSIS | targets | phenotype | 0.65 |
| SRPK1 | associated_with | concept | 0.50 |
| CENTRAL NERVOUS SYSTEM | protects_against | concept | 0.50 |
| HIPPO PATHWAY | associated_with | pathway | 0.45 |
| EGFR | co_discussed | gene | 0.40 |
| LRP1 | co_discussed | gene | 0.40 |
| PI3K | co_discussed | gene | 0.40 |
| METASTASIS | co_discussed | process | 0.40 |
| CELL PROLIFERATION | co_discussed | process | 0.40 |
| MULTIPLE SCLEROSIS | co_discussed | disease | 0.40 |
| NEURON | implicated_in | cell_type | 0.35 |
| FIBROBLASTS | activates | cell_type | 0.35 |
| METASTASIS | regulates | process | 0.35 |
| PI3K | phosphorylates | gene | 0.35 |
| CELL PROLIFERATION | associated_with | process | 0.35 |
| MULTIPLE SCLEROSIS | inhibits | disease | 0.35 |
| METASTASIS | associated_with | process | 0.35 |
| HEPATOCELLULAR CARCINOMA | therapeutic_target | disease | 0.35 |
| NEUROINFLAMMATION | regulates | process | 0.35 |
| MONOCYTES | activates | cell_type | 0.35 |
| EGFR | activates | gene | 0.35 |
| INFLAMMATION | associated_with | process | 0.35 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ABLIM1 | promotes | protein | 0.93 |
| PSME2 | inhibits | gene | 0.92 |
| MMP9 | promotes | gene | 0.90 |
| MMP2 | promotes | gene | 0.90 |
| USP36 | associated_with | enzyme | 0.90 |
| Chrysotoxine | inhibits | compound | 0.90 |
| IGF2BP2 | associated_with | gene | 0.90 |
| TUBB3 | promotes | gene | 0.90 |
| PI3K/AKT | promotes | pathway | 0.90 |
| MAPK | regulates | pathway | 0.90 |
| TRIM34 | promotes | gene | 0.90 |
| Aloperine | inhibits | compound | 0.90 |
| BIG1 | associated_with | gene | 0.90 |
| RGFP966 | suppresses | drug | 0.90 |
| Hu-Loaded Exosomes | inhibits | compound | 0.90 |
| Cinobufagin | inhibits | compound | 0.88 |
| OCLN | inhibits | protein | 0.88 |
| IGF2 | involved_in | protein | 0.85 |
| SATB2 | inhibits | protein | 0.85 |
| MMP9 | promotes | gene | 0.85 |
| MMP2 | promotes | gene | 0.85 |
| CLDN3 | promotes | gene | 0.85 |
| Cardamom Nanoemulsion | inhibits | compound | 0.85 |
| CLDN4 | promotes | gene | 0.85 |
| EB3 | regulates | protein | 0.80 |
| IGF2R | regulates | protein | 0.80 |
| PTEN | regulates | gene | 0.80 |
| FOXO1 | regulates | gene | 0.80 |
| EB1 | regulates | protein | 0.80 |
| DLG1 | involved_in | gene | 0.80 |
| RPS21 | inhibits | gene | 0.80 |
| CSNK1D | regulates | gene | 0.80 |
| FOXO1 | suppresses | gene | 0.75 |
| Serotonin | promotes | compound | 0.75 |
| AQP4 | involved_in | protein | 0.75 |
| EIF2B3 | participates_in | gene | 0.70 |
| PI3K | regulates | protein | 0.70 |
| SPHINGOLIPIDS | interacts_with | phenotype | 0.65 |
| VEGF | inhibits | gene | 0.65 |
| EGFR | causes | gene | 0.65 |
| CASS4 | involved_in | protein | 0.60 |
| Egfr Signaling | activates | pathway | 0.50 |
| cancer | activates | disease | 0.50 |
| HIPPO | activates | concept | 0.50 |
| EGFR | activates | gene | 0.50 |
| EXTRACELLULAR MATRIX | activates | concept | 0.50 |
| Tumor Microenvironment | activates | process | 0.50 |
| SPTLC1 | activates | gene | 0.50 |
| atherosclerosis | activates | disease | 0.50 |
| MONOCYTE | activates | concept | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning CELL MIGRATION in their description or question text
No additional research found