concept

CLDN3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CLDN3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

21Connections

0Hypotheses

0Analyses

18Outgoing

3Incoming

0Experiments

0Debates

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💡 Concept Info

Name	CLDN3
Key Genes/Proteins	CLDN1, CLDN4, CLDN5, GBM
Related Diseases	Cancer, glioblastoma, Glioblastoma, Glioblastoma Multiforme

Pathway Diagram

graph TD
    CLDN3[CLDN3]
    CLDN3 -->|promotes| Glioma_Migration[Glioma Migration]
    CLDN3 -->|promotes| Glioblastoma[Glioblastoma]
    CLDN3 -->|promotes| Metastasis[Metastasis]
    CLDN3 -->|promotes| Glioblastoma_Multiforme[Glioblastoma Multiforme]
    CLDN3 -->|promotes| cell_proliferation[cell proliferation]
    CLDN3 -->|promotes| cell_migration[cell migration]
    CLDN3 -->|contributes to| Cancer[Cancer]
    CLDN3 -->|promotes| tumor_cell_proliferation[tumor cell proliferation]
    CLDN3 -->|promotes| tumor_cell_migration[tumor cell migration]
    CLDN3 -->|promotes| metastasis[metastasis]
    CLDN1[CLDN1] -->|expressed in| CLDN3
    benchmark_ot_ad_answer_key_CLD[benchmark_ot_ad_answer_key:CLDN3] -->|data_in| CLDN3

Outgoing (18)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:CLDN3	data_in	dataset_row	0.00
Glioblastoma	promotes	disease	0.90
Metastasis	promotes	process	0.90
Glioma Migration	promotes	process	0.90
cell migration	promotes	process	0.85
Glioblastoma Multiforme	promotes	disease	0.85
Cancer	contributes_to	disease	0.85
cell proliferation	promotes	process	0.85
tumor cell proliferation	promotes	process	0.80
tumor cell migration	promotes	process	0.80
metastasis	promotes	process	0.80
Glioblastoma	biomarker_for	disease	0.75
tumor metastasis	promotes	process	0.75
Glioblastoma Multiforme	biomarker_for	disease	0.70
CLDN5	expressed_in	gene	0.60
GBM	activates	gene	0.60
CLDN4	activates	gene	0.60
glioblastoma	activates	disease	0.60

Incoming (3)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:CLDN3	data_in	dataset_row	0.00
CLDN1	expressed_in	gene	0.60
CLDN1	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CLDN3 in their description or question text

No additional research found