SYK

Understanding Entity Pages

This page aggregates everything SciDEX knows about SYK: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

A gene referenced in 1 knowledge graph relationship. Key connections: encodes SYK_kinase (protein).

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graph TD
    SYK["SYK"]
    Alzheimer{"Alzheimer"}
    SYK -->|"activates"| Alzheimer
    Ms{"Ms"}
    SYK -->|"activates"| Ms
    SYK -->|"associated with"| Alzheimer
    TFEB["TFEB"]
    SYK -->|"associated with"| TFEB
    TREM2["TREM2"]
    SYK -->|"associated with"| TREM2
    Als{"Als"}
    SYK -->|"interacts with"| Als
    Obesity{"Obesity"}
    SYK -->|"activates"| Obesity
    Depression{"Depression"}
    SYK -->|"expressed in"| Depression
    SYK -->|"activates"| TREM2
    Apoptosis(["Apoptosis"])
    SYK -->|"activates"| Apoptosis
    Amyloid(["Amyloid"])
    SYK -->|"associated with"| Amyloid
    SYK -->|"associated with"| Apoptosis
    AKT["AKT"]
    AKT -->|"associated with"| SYK
    PI3K["PI3K"]
    PI3K -->|"associated with"| SYK
    APOE["APOE"]
    APOE -->|"associated with"| SYK
    MICROGLIA["MICROGLIA"]
    MICROGLIA -->|"activates"| SYK
    TREM2 -->|"expressed in"| SYK
    IL6["IL6"]
    IL6 -->|"expressed in"| SYK
    IL1B["IL1B"]
    IL1B -->|"expressed in"| SYK
    IL10["IL10"]
    IL10 -->|"expressed in"| SYK
    TAU["TAU"]
    TAU -->|"expressed in"| SYK
    APOPTOSIS["APOPTOSIS"]
    APOPTOSIS -->|"activates"| SYK
    AMYLOID["AMYLOID"]
    AMYLOID -->|"activates"| SYK
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"activates"| SYK
    style SYK fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

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