concept

RALGAPA2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RALGAPA2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

42Connections

0Hypotheses

0Analyses

20Outgoing

22Incoming

0Experiments

0Debates

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💡 Concept Info

Name	RALGAPA2
Key Genes/Proteins	ASC, ATG, BECN1, BRG1, CCDC50, CLDN2
Related Diseases	cancer, CRC
Related Pathways	autophagy pathway

Pathway Diagram

graph TD
    RALGAPA2[RALGAPA2]
    RALGAPA2 -->|activates| RIPK2[RIPK2]
    RALGAPA2 -->|activates| RIPK3[RIPK3]
    RALGAPA2 -->|activates| SMARCA4[SMARCA4]
    RALGAPA2 -->|activates| SNF[SNF]
    RALGAPA2 -->|activates| SQSTM1[SQSTM1]
    RALGAPA2 -->|activates| STAT3[STAT3]
    RALGAPA2 -->|activates| SWI[SWI]
    RALGAPA2 -->|activates| TNF[TNF]
    RALGAPA2 -->|activates| TNFA[TNFA]
    RALGAPA2 -->|activates| ULK1[ULK1]
    ASC[ASC] -->|activates| RALGAPA2
    BECN1[BECN1] -->|activates| RALGAPA2
    BRG1[BRG1] -->|activates| RALGAPA2
    CLDN2[CLDN2] -->|activates| RALGAPA2
    ERN1[ERN1] -->|activates| RALGAPA2
    IRGM1[IRGM1] -->|activates| RALGAPA2
    LC3[LC3] -->|activates| RALGAPA2
    MELK[MELK] -->|activates| RALGAPA2
    MTOR[MTOR] -->|activates| RALGAPA2
    NLRP3[NLRP3] -->|activates| RALGAPA2

Outgoing (20)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:RALGAPA2	data_in	dataset_row	0.00
RIPK2	activates	gene	0.60
RIPK3	activates	gene	0.60
SMARCA4	activates	gene	0.60
SNF	activates	gene	0.60
SQSTM1	activates	gene	0.60
STAT3	activates	gene	0.60
SWI	activates	gene	0.60
TNF	activates	gene	0.60
TNFA	activates	gene	0.60
ULK1	activates	gene	0.60
cancer	activates	disease	0.60
PI3K-AKT-mTOR signaling	participates_in	pathway	0.60
oxidative stress response	participates_in	pathway	0.60
necroptosis	participates_in	pathway	0.60
autophagy pathway	participates_in	pathway	0.60
ROS	activates	gene	0.60
MAPK signaling	participates_in	pathway	0.60
CRC	associated_with	disease	0.60
stem cells	expressed_in	cell_type	0.55

Incoming (22)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:RALGAPA2	data_in	dataset_row	0.00
ASC	activates	gene	0.60
BECN1	activates	gene	0.60
BRG1	activates	gene	0.60
CLDN2	activates	gene	0.60
ERN1	activates	gene	0.60
IRGM1	activates	gene	0.60
LC3	activates	gene	0.60
MELK	activates	gene	0.60
MTOR	activates	gene	0.60
NLRP3	activates	gene	0.60
NOD2	activates	gene	0.60
PI3K	activates	gene	0.60
PYCARD	activates	gene	0.60
ATG	activates	gene	0.60
CCDC50	activates	gene	0.60
IKK	activates	gene	0.60
MAP1LC3	activates	gene	0.60
MAPK	activates	gene	0.60
NLR	activates	gene	0.60
NRBF2	activates	gene	0.60
rapamycin	targets	drug	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning RALGAPA2 in their description or question text

No additional research found