Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Invasion: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No summary available yet.
No AI portrait yet
| Name | Invasion |
| Key Genes/Proteins | ABCA1, ACAT1, ACETYL-COA, AGING, AGO2, AKT |
| Related Diseases | aging, Aging, Als, Alzheimer |
graph TD
Invasion["Invasion"]
CANCER(["CANCER"])
CANCER -->|"activates"| Invasion
Tumor{"Tumor"}
Tumor -->|"therapeutic_target"| Invasion
Cancer{"Cancer"}
Cancer -->|"activates"| Invasion
Als{"Als"}
Als -->|"therapeutic_target"| Invasion
style Invasion fill:#1a3a4a,stroke:#81c784,stroke-width:3px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| STEM CELLS | activates | concept | 0.50 |
| CELL PROLIFERATION | associated_with | concept | 0.50 |
| PDGF | expressed_in | concept | 0.50 |
| FIBROBLASTS | activates | concept | 0.50 |
| CELL MIGRATION | activates | concept | 0.50 |
| Tumor Microenvironment | regulates | process | 0.50 |
| PI3K/AKT/mTOR | causes | pathway | 0.50 |
| Tumor Microenvironment | interacts_with | process | 0.50 |
| PI3K/AKT SIGNALING | inhibits | concept | 0.50 |
| EXTRACELLULAR VESICLES | activates | concept | 0.50 |
| IL-6 SIGNALING | activates | concept | 0.50 |
| Proteins | activates | protein | 0.50 |
| EXTRACELLULAR MATRIX | activates | concept | 0.50 |
| Epithelial-Mesenchymal Transition | activates | process | 0.50 |
| CELL MIGRATION | associated_with | concept | 0.50 |
| Proteins | expressed_in | protein | 0.50 |
| CELL PROLIFERATION | inhibits | concept | 0.50 |
| SRPK1 | associated_with | concept | 0.50 |
| SRPK1 | inhibits | concept | 0.50 |
| CELL PROLIFERATION | activates | concept | 0.50 |
| CENTRAL NERVOUS SYSTEM | activates | concept | 0.50 |
| Tumor Microenvironment | associated_with | process | 0.50 |
| Melanoma | associated_with | disease | 0.50 |
| Proteins | inhibits | protein | 0.50 |
| Source | Relation | Type | Str |
|---|---|---|---|
| PI3K | activates | gene | 1.00 |
| APOPTOSIS | therapeutic_target | gene | 1.00 |
| Tumor | therapeutic_target | disease | 1.00 |
| P53 | activates | gene | 1.00 |
| GENES | activates | gene | 1.00 |
| Als | activates | disease | 1.00 |
| APOPTOSIS | activates | gene | 1.00 |
| Cancer | activates | disease | 1.00 |
| Carcinoma | therapeutic_target | disease | 1.00 |
| INFLAMMATION | activates | gene | 1.00 |
| Als | inhibits | disease | 1.00 |
| Inflammation | activates | disease | 1.00 |
| Als | therapeutic_target | disease | 1.00 |
| AKT | therapeutic_target | gene | 1.00 |
| CANCER | activates | gene | 1.00 |
| Tumor | associated_with | disease | 1.00 |
| PI3K | therapeutic_target | gene | 1.00 |
| Carcinoma | activates | disease | 1.00 |
| AKT | activates | gene | 1.00 |
| ERK | activates | gene | 1.00 |
| Cancer | inhibits | disease | 1.00 |
| ROS | activates | gene | 1.00 |
| Tumor | inhibits | disease | 1.00 |
| CANCER | inhibits | gene | 1.00 |
| CANCER | expressed_in | gene | 1.00 |
| Als | regulates | disease | 1.00 |
| Cancer | expressed_in | disease | 1.00 |
| Lung Cancer | activates | disease | 1.00 |
| CANCER | therapeutic_target | gene | 1.00 |
| AUTOPHAGY | activates | gene | 1.00 |
| Tumor | activates | disease | 1.00 |
| GENES | regulates | gene | 1.00 |
| STAT3 | activates | gene | 1.00 |
| BAX | activates | gene | 1.00 |
| Cancer | regulates | disease | 1.00 |
| CANCER | regulates | gene | 1.00 |
| APOPTOSIS | regulates | gene | 1.00 |
| Cancer | therapeutic_target | disease | 1.00 |
| Tumor | expressed_in | disease | 1.00 |
| UBIQUITIN | activates | gene | 1.00 |
| AKT | inhibits | gene | 1.00 |
| Cancer | associated_with | disease | 1.00 |
| CANCER | associated_with | gene | 1.00 |
| Colorectal Cancer | therapeutic_target | disease | 1.00 |
| PI3K | inhibits | gene | 1.00 |
| Breast Cancer | inhibits | disease | 1.00 |
| Tumor | regulates | disease | 1.00 |
| APOPTOSIS | associated_with | gene | 1.00 |
| PI3K | regulates | gene | 1.00 |
| Jak-Stat3 | associated_with | pathway | 0.90 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning Invasion in their description or question text
No additional research found