concept

SLC13A3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SLC13A3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

18Connections

0Hypotheses

0Analyses

11Outgoing

7Incoming

0Experiments

0Debates

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💡 Concept Info

Name	SLC13A3
Key Genes/Proteins	CTNNB1, GSH, MTOR, MYC, NRF2, SLC7A5
Related Diseases	ferroptosis resistance, liver cancer
Related Pathways	autophagy pathway

Pathway Diagram

graph TD
    SLC13A3[SLC13A3]
    SLC13A3 -->|promotes| ferroptosis_resistance[ferroptosis resistance]
    SLC13A3 -->|target for| liver_cancer[liver cancer]
    SLC13A3 -->|promotes| ferroptosis[ferroptosis]
    SLC13A3 -->|activates| NRF2[NRF2]
    SLC13A3 -->|upstream_of| MTOR[MTOR]
    SLC13A3 -->|inhibits| immune_checkpoint_blockade[immune checkpoint blockade]
    SLC13A3 -->|regulates| MYC[MYC]
    SLC13A3 -->|inhibits| SLC7A5[SLC7A5]
    SLC13A3 -->|participates in| autophagy_pathway[autophagy pathway]
    CTNNB1[CTNNB1] -->|upstream_of| SLC13A3
    MYC -->|inhibits| SLC13A3
    GSH[GSH] -->|translocates_to| SLC13A3
    benchmark_ot_ad_answer_key_SLC[benchmark_ot_ad_answer_key:SLC13A3] -->|data_in| SLC13A3

Outgoing (11)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:SLC13A3	data_in	dataset_row	0.00
ferroptosis resistance	promotes	phenotype	0.95
liver cancer	therapeutic_target	disease	0.93
ferroptosis	promotes	process	0.92
NRF2	activates	protein	0.90
MTOR	upstream_of	gene	0.88
MYC	regulates	gene	0.85
immune checkpoint blockade	inhibits	process	0.85
ferroptosis	participates_in	pathway	0.60
SLC7A5	inhibits	gene	0.60
autophagy pathway	participates_in	pathway	0.60

Incoming (7)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:SLC13A3	data_in	dataset_row	0.00
CTNNB1	upstream_of	gene	0.95
GSH	translocates_to	gene	0.60
GSH	activates	gene	0.60
CTNNB1	expressed_in	gene	0.60
MYC	inhibits	gene	0.60
CTNNB1	targets	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SLC13A3 in their description or question text

No additional research found