gene 649 words KG: DLC1
Contents

DLC1 Gene - Deleted in Liver Cancer 1

🧬 Gene Info
Gene SymbolDLC1
AliasesPage for DLC1 Gene
Chromosome8p22.
FunctionDLC1 (Deleted in Liver Cancer 1) is a GTPase-activating protein (GAP) that specifically inactivates Rho family GTPases, primarily RhoA, Rac1, and Cdc42.
Primary Expressiondopaminergic neurons where it may protect against oxidative stress
PathwaysApoptosis, Wnt, Mapk
Ensembl IDENSG00000121667
GeneCardsDLC1
Human Protein AtlasDLC1
Associated Diseasesneurodegeneration
InteractionsAPOPTOSIS, CANCER, CD44, FGF10, KCNH1, KCNK2
KG Connections25 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Knowledge Graph (12 edges)

CDKN2A associated_with DLC1
TLR4 inhibits DLC1
TNC inhibits DLC1
NTRK2 inhibits DLC1
PAK1 inhibits DLC1
WNT7A associated_with DLC1
LZTS1 associated_with DLC1
DCC associated_with DLC1
KCNK2 inhibits DLC1
CD44 inhibits DLC1

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