protein

CYTOCHROME C

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CYTOCHROME C: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

69Connections

0Hypotheses

0Analyses

31Outgoing

38Incoming

0Experiments

0Debates

Summary

Page for Cytochrome c Protein

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🔬 Protein Info

Gene Symbol	CYTOCHROME C
Molecular Weight	11.7 kDa
Amino Acids	104 aa
Pathways	Intrinsic Apoptosis
Known Drugs/Compounds	ANTHOCYANINS, Methylene Blue
Interactions	ATG7, BCL2, BCL2L13, BNIP3L, COX4I1, FOXO3
KG Connections	64 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Pathway Diagram

graph TD
    CYTOCHROME_C["CYTOCHROME C"]
    Intrinsic_Apoptosis["Intrinsic Apoptosis"]
    CYTOCHROME_C -->|"involved in"| Intrinsic_Apoptosis
    Apoptosis["Apoptosis"]
    CYTOCHROME_C -->|"mediates"| Apoptosis
    Methylene_Blue["Methylene Blue"]
    Methylene_Blue -->|"interacts with"| CYTOCHROME_C
    UBIQUITIN["UBIQUITIN"]
    CYTOCHROME_C -->|"interacts with"| UBIQUITIN
    ATG7["ATG7"]
    CYTOCHROME_C -->|"interacts with"| ATG7
    LC3B["LC3B"]
    CYTOCHROME_C -->|"interacts with"| LC3B
    COX4I1["COX4I1"]
    CYTOCHROME_C -->|"interacts with"| COX4I1
    apoptosis["apoptosis"]
    CYTOCHROME_C -->|"interacts with"| apoptosis
    ISCHEMIA["ISCHEMIA"]
    CYTOCHROME_C -->|"interacts with"| ISCHEMIA
    BRAIN_INJURY["BRAIN INJURY"]
    CYTOCHROME_C -->|"interacts with"| BRAIN_INJURY
    ISCHEMIC["ISCHEMIC"]
    CYTOCHROME_C -->|"interacts with"| ISCHEMIC
    OPTINEURIN["OPTINEURIN"]
    CYTOCHROME_C -->|"activates"| OPTINEURIN
    UBIQUITIN["UBIQUITIN"]
    CYTOCHROME_C -->|"activates"| UBIQUITIN
    HSP60["HSP60"]
    CYTOCHROME_C -->|"activates"| HSP60
    LC3B["LC3B"]
    CYTOCHROME_C -->|"activates"| LC3B
    COX4I1["COX4I1"]
    CYTOCHROME_C -->|"activates"| COX4I1
    mitophagy["mitophagy"]
    CYTOCHROME_C -->|"activates"| mitophagy
    BRAINSTEM["BRAINSTEM"]
    CYTOCHROME_C -->|"activates"| BRAINSTEM
    GLUTAMATE["GLUTAMATE"]
    CYTOCHROME_C -->|"activates"| GLUTAMATE
    MTDNA["MTDNA"]
    CYTOCHROME_C -->|"activates"| MTDNA
    Neurodegenerative_Diseases["Neurodegenerative Diseases"]
    CYTOCHROME_C -->|"activates"| Neurodegenerative_Diseases
    Unfolded_Protein_Response["Unfolded Protein Response"]
    CYTOCHROME_C -->|"activates"| Unfolded_Protein_Response
    Reactive_Oxygen_Species["Reactive Oxygen Species"]
    CYTOCHROME_C -->|"activates"| Reactive_Oxygen_Species
    oxidative_stress["oxidative stress"]
    CYTOCHROME_C -->|"activates"| oxidative_stress
    NADH["NADH"]
    CYTOCHROME_C -->|"activates"| NADH
    apoptosis["apoptosis"]
    CYTOCHROME_C -->|"associated with"| apoptosis
    apoptosis["apoptosis"]
    CYTOCHROME_C -->|"regulates"| apoptosis
    Lymphoma["Lymphoma"]
    CYTOCHROME_C -->|"regulates"| Lymphoma
    B_Cell["B Cell"]
    CYTOCHROME_C -->|"regulates"| B_Cell
    Autophagy["Autophagy"]
    Autophagy -->|"interacts with"| CYTOCHROME_C

Outgoing (31)

Target	Relation	Type	Str
Intrinsic Apoptosis	involved_in	pathway	0.95
Apoptosis	mediates	process	0.90
Neuroinflammation	promotes	process	0.85
Primary Afferent Sensory Fiber Degeneration	mediates	phenotype	0.85
neuroinflammation	associated_with	process	0.80
oxidative stress	activates	phenotype	0.50
NADH	activates	concept	0.50
UBIQUITIN	interacts_with	protein	0.50
ATG7	interacts_with	protein	0.50
LC3B	interacts_with	protein	0.50
COX4I1	interacts_with	gene	0.50
apoptosis	interacts_with	process	0.50
ISCHEMIA	interacts_with	disease	0.50
BRAIN INJURY	interacts_with	concept	0.50
ISCHEMIC	interacts_with	concept	0.50
OPTINEURIN	activates	protein	0.50
UBIQUITIN	activates	protein	0.50
HSP60	activates	protein	0.50
LC3B	activates	protein	0.50
COX4I1	activates	gene	0.50
mitophagy	activates	pathway	0.50
BRAINSTEM	activates	concept	0.50
GLUTAMATE	activates	concept	0.50
MTDNA	activates	gene	0.50
Neurodegenerative Diseases	activates	disease	0.50
Unfolded Protein Response	activates	pathway	0.50
Reactive Oxygen Species	activates	process	0.50
apoptosis	associated_with	process	0.50
apoptosis	regulates	process	0.50
Lymphoma	regulates	disease	0.50
B Cell	regulates	cell_type	0.50

Incoming (38)

Source	Relation	Type	Str
BCL2	regulates	protein	0.95
BCL2	regulates	gene	0.90
Methylene Blue	interacts_with	drug	0.90
ANTHOCYANINS	inhibits	compound	0.80
caspases	activates	disease	0.50
MITOCHONDRIA	regulates	cell_type	0.50
BCL2	regulates	gene	0.50
MITOCHONDRIA	associated_with	cell_type	0.50
MITOCHONDRIA	interacts_with	cell_type	0.50
PARK2	interacts_with	gene	0.50
PARKIN	interacts_with	gene	0.50
SQSTM1	interacts_with	gene	0.50
MAP1LC3B	interacts_with	gene	0.50
PRKN	interacts_with	gene	0.50
MAP1LC3A	interacts_with	gene	0.50
GAPDH	interacts_with	gene	0.50
BCL2L13	interacts_with	gene	0.50
TOMM20	interacts_with	gene	0.50
BCL2	interacts_with	gene	0.50
BNIP3L	interacts_with	protein	0.50
MITOCHONDRIA	activates	cell_type	0.50
OPTN	activates	gene	0.50
PARKIN	activates	gene	0.50
PTEN	activates	gene	0.50
PINK1	activates	gene	0.50
MAP1LC3B	activates	gene	0.50
MYO7A	activates	gene	0.50
PRKN	activates	gene	0.50
XBP1	activates	gene	0.50
GRIA2	activates	gene	0.50
USP30	activates	gene	0.50
HSPD1	activates	gene	0.50
TOMM20	activates	gene	0.50
FOXO3	activates	gene	0.50
Neuroinflammation	activates	process	0.50
TFAM	activates	gene	0.50
LRPPRC	associated_with	gene	0.50
Autophagy	interacts_with	process	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CYTOCHROME C in their description or question text

No additional research found